Results 11 to 20 of about 38,650 (260)
Pyridoxal-5′-phosphate-dependent catalytic antibodies [PDF]
Cofactors—i.e., metal ions and coenzymes—extend the catalytic scope of enzymes and might have been among the first biological catalysts. They may be expected to efficiently extend the catalytic potential of antibodies.
Christen, Philipp, Gramatikova, Svetlana
core +8 more sources
A New Synthesis of Pyridoxal-5-phosphate [PDF]
Abstract By the hydrolysis of pyridoxal-5-phosphate Schiff bases, pyridoxal-5-phosphate was prepared in a crystalline form without any further purification. Pyridoxal-5-phosphate Schiff bases were prepared in good yields by the phosphorylation of pyridoxal Scruff bases and were easily purified by alkali-acid reprecipitation.
Masaru Iwanami+2 more
openalex +4 more sources
Association between serum pyridoxal 5′-phosphate levels and chronic obstructive pulmonary disease: findings based on NHANES 2005–2010 [PDF]
ObjectiveVitamin B6 is involved in regulating a variety of biological reactions in cell metabolism, and possesses antioxidant and anti-inflammatory biological functions.
Yanbin Liu, Jun Yan
doaj +2 more sources
Background: A case in which a 45-year-old female patient with peritonitis experienced immediate-type hypersensitivity on two occasions after administration of preparations containing six different medications was referred to us for closer inspection ...
Masako Osada+5 more
doaj +2 more sources
A novel synthesis of pyridoxal-5'-phosphate.
Pyridoxal-5′-phosphate was synthesized in excellent yield by phosphorylation of 1-secondaryammo-l,3-dihydro-7-hydroxy-6-methyl-furo(3,4-c)pyridine which was readily obtained by a condensation reaction between pyridoxal and a secondary amine.
Kunio Nakagawa+3 more
openalex +4 more sources
Inactivation of Rhodanese by Pyridoxal 5′‐Phosphate [PDF]
Pyridoxal 5′‐phosphate and other aromatic aldehydes inactivate rhodanese. This inactivation reaches higher extents if the enzyme is in the sulfur‐free form. The identification of the reactive residue as an amino group has been made by spectrophotometric determination of the 5′‐phosphorylated pyridoxyl derivative of the enzyme.
C. Cannella+4 more
openalex +4 more sources
Pyridoxal 5'-phosphate(PLP)is known to combine with bovine serum albumin to form a (1:1) complex which scarcely dissociates, even when subjected to intensive dialysis. When this complex was incubated with apo-aspartate aminotransferase (apoCOT)for an appropriate time and the preincubated mixture then submitted to the usual GOT assay, the appearance of ...
Fuminori Masugi+3 more
openalex +5 more sources
Pyridoxal 5'-Phosphate Biosynthesis by Pyridox-(am)-ine 5'-Phosphate Oxidase: Species-Specific Features. [PDF]
Enzymes reliant on pyridoxal 5'-phosphate (PLP), the metabolically active form of vitamin B6, hold significant importance in both biology and medicine. They facilitate various biochemical reactions, particularly in amino acid and neurotransmitter metabolisms. Vitamin B6 is absorbed by organisms in its non-phosphorylated form and phosphorylated
Rivero M, Novo N, Medina M.
europepmc +5 more sources
Simultaneous Determination of Underivatized Vitamin B1 and B6 in Whole Blood by Reversed Phase Ultra High Performance Liquid Chromatography Tandem Mass Spectrometry. [PDF]
Vitamin B1 (thiamine-diphosphate) and B6 (pyridoxal-5'phosphate) are micronutrients. Analysis of these micronutrients is important to diagnose potential deficiency which often occurs in elderly people due to malnutrition, in severe alcoholism and in ...
Johan Puts+3 more
doaj +1 more source