Results 101 to 110 of about 908,246 (301)

An eye on long‐duration spaceflight: Controversies, countermeasures and challenges

Experimental Physiology, EarlyView.
Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng, Susan Patricia Mollan   +1 more
wiley   +1 more source

Lysine-restricted diet and mild cerebral serotonin deficiency in a patient with pyridoxine-dependent epilepsy caused by ALDH7A1 genetic defect

Molecular Genetics and Metabolism Reports, 2014
Pyridoxine dependent epilepsy (PDE) is caused by mutations in the ALDH7A1 gene (PDE-ALDH7A1) encoding α-aminoadipic-semialdehyde-dehydrogenase enzyme in the lysine catabolic pathway resulting in an accumulation of α-aminoadipic-acid-semialdehyde (α-AASA).
Saadet Mercimek-Mahmutoglu, Dawn Corderio, Laura Nagy, Carly Mutch, Melissa Carter, Eduard Struys, Lianna Kyriakopoulou   +6 more
doaj   +1 more source

Molecular mechanisms associated with rootstock–scion interactions in rubber trees

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Hevea brasiliensis (rubber tree) is the main source of natural rubber worldwide. In commercial plantations, high‐yield rubber tree clones are propagated by grafting onto seedling rootstocks. In this study, the transcriptomes of the RRIM 600 clone grafted on different rootstocks in southeastern Brazil were evaluated. Exclusively expressed genes
Wanderson Lima Cunha, Vinicius Mandolesi Rios, Alexandre Hild Aono, Danilo Augusto Sforça, Aline Da Costa Lima Moraes, Milene Silvestrini, Jose Marcos Dias Ferreira Junior, Antonio Lucio Mello Martins, Elaine Cristine Piffer Gonçalves, Paulo de Souza Gonçalves, Felipe Roberto Francisco, Anete Pereira de Souza   +11 more
wiley   +1 more source

Role of pyridoxine and oxidative stress in asthenozoospermia

Heliyon
Purpose: Infertility is a worldwide concern, and recent research indicates that vitamin B6 deficiency may play a role in male infertility, primarily by inducing hyperhomocysteinemia and oxidative stress.
Roba Bdeir, Shefa’ Muneer Aljabali, Saleem Ali Banihani   +2 more
doaj   +1 more source

Key Determinants of Weight Loss Trajectory Across Different Periods of a Behavioral Weight Loss Intervention

Obesity, Volume 34, Issue 2, Page 357-371, February 2026.
ABSTRACT Objective This longitudinal study aims to identify the key factors influencing the weight loss trajectory during a 24‐week intervention and their relevance at different stages of the treatment. Methods We studied 1252 participants (age 18–65 years) of a cognitive behavioral program to lose weight.
Rocío De la Peña‐Armada, Giovana Longo‐Silva, María Rodríguez‐Martín, Hui‐Wen Yang, Marta Garaulet   +4 more
wiley   +1 more source

Investigating operational stability and causes of cofactor release in fold type I amine transaminase

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Amine transaminases (ATAs) are pyridoxal phosphate (PLP) dependent biocatalysts frequently employed in chiral amine synthesis. Yields of ATA‐catalyzed reactions often suffer from low enzyme operational stability due to weak interactions between the ATA and the aminated cofactor pyridoxamine phosphate (PMP), which can leak from the active site ...
Xuebin Feng, William Chau, Emma R. Master   +2 more
wiley   +1 more source

Effects of pyridoxine deficiency and dl-p-chlorophenylalanine administration to rats on 5-hydroxytryptamine and noradrenaline concentrations in brain and 5-hydroxytryptamine concentration in blood [PDF]

, 1973
H. N. Bhagavan, David Baird Coursin
openalex   +1 more source

The Role of the Gut Microbiome in the Complex Network of Frailty Syndrome and Associated Comorbidities in Aging

Aging Cell, Volume 25, Issue 2, February 2026.
This study analyzed gut microbiota in older adults with and without Frailty Syndrome by 16S rRNA gene sequencing and metagenomics. Frailty was associated with altered microbial composition, metabolic functions, and increased antimicrobial resistance, whereas non‐frail individuals showed healthier profiles.
Ana Barberá, Rosario Ortolá, Mercedes Sotos‐Prieto, Fernando Rodríguez‐Artalejo, Andrés Moya, Susana Ruiz‐Ruiz   +5 more
wiley   +1 more source

Selection for Postponed Senescence in Drosophila melanogaster Reveals Distinct Metabolic Aging Trajectories Modifiable by the Angiotensin‐Converting Enzyme Inhibitor Lisinopril

Aging Cell, Volume 25, Issue 2, February 2026.
Assessment of oxygen consumption rates in young, middle‐aged, and old flies from the Drosophila B lines and long‐lived O lines revealed a significant increase in metabolic rate with aging only in B flies. Lisinopril prevented the age‐related rise in metabolic rate in B female flies.
Denise Vecchié, Robert R. H. Anholt, Trudy F. C. Mackay, Maria De Luca   +3 more
wiley   +1 more source

Genome Sequence and Population Genomic Analysis of Cronartium quercuum f.sp. fusiforme

Forest Pathology, Volume 56, Issue 1, February 2026.
ABSTRACT Fusiform rust, caused by Cronartium quercuum f. sp. fusiforme (Cqf), is the most severe disease of planted southern pines in the south‐eastern United States. Despite the critical role pathogen genomics play in disease outcomes, the population structure and genetic variability of Cqf remain poorly characterised.
Makayla Rutski, Tania Quesada, Katherine Smith, Ina Schlathoelter, Jeremy T. Brawner, C. Dana Nelson, John M. Davis, Gary F. Peter   +7 more
wiley   +1 more source