Results 111 to 120 of about 908,246 (301)

Novel variants in a patient with late-onset hyperprolinemia type II: diagnostic key for status epilepticus and lactic acidosis

BMC Neurology, 2019
Background Hyperprolinemia type 2 (HPII) is a rare autosomal recessive disorder of the proline metabolism, that affects the ALDH4A1 gene. So far only four different pathogenic mutations are known.
Jeremias Motte, Anna Lena Fisse, Thomas Grüter, Ruth Schneider, Thomas Breuer, Thomas Lücke, Stefan Krueger, Huu Phuc Nguyen, Ralf Gold, Ilya Ayzenberg, Gisa Ellrichmann   +10 more
doaj   +1 more source

Low cellular pyridoxal 5ʹ-phosphate levels decrease neurotransmitter and glutathione concentrations and increase susceptibility to hydrogen peroxide toxicity in SH-SY5Y cells

Clinical Nutrition Open Science
Summary: Objectives: Pyridoxal 5ʹ-phosphate (PLP) is an active and major form of vitamin B6 (VB6) in the body. PLP is essential as a cofactor for many enzymes involved in amino acid metabolism, and VB6 deficiency is associated with neurological ...
Nana Itoh, Shigenobu Matsumura, Toshio Iwaki, Shigeo Takenaka, Hiroaki Kanouchi   +4 more
doaj   +1 more source

PYRIDOXINE DEFICIENCY IN HUMAN BEINGS INDUCED WITH DESOXYPYRIDOXINE 1 [PDF]

, 1950
John F. Mueller, Richard W. Vilter
openalex   +1 more source

ANEMIA, HYPOPROTEINEMIA, AND CATARACTS IN SWINE FED CASEIN HYDROLYSATE OR ZEIN. COMPARISON WITH PYRIDOXINE-DEFICIENCY ANEMIA 1 [PDF]

, 1945
G. E. Cartwright, M. M. Wintrobe, Wilhelm Buschke, R. H. Follis, A. Suksta, S. Humphreys   +5 more
openalex   +1 more source

Asymmetric Synthesis of Atropisomeric Amines via Transaminase‐Catalyzed Dynamic Kinetic Resolution

Advanced Synthesis &Catalysis, Volume 368, Issue 2, January 2026.
A dynamic kinetic resolution approach is developed for the atroposelective synthesis of heterobiaryl primary amines. Using transaminases and leveraging Lewis acid‐base interactions to induce racemization, a variety of axially chiral primary amines are produced in high yields and enantioselectivities.
Juan M. Coto‐Cid, Patricia Rodríguez‐Salamanca, Christian M. Heckmann, Caroline E. Paul, Joaquín López‐Serrano, Rosario Fernández, José M. Lassaletta, Valentín Hornillos, Gonzalo de Gonzalo   +8 more
wiley   +1 more source

FREQUENCY AND METHODS OF CORRECTION OF MAGNESIUM DEFICIENCY IN YOUNG WOMEN OF REPRODUCTIVE AGE AT TAKING COMBINED ORAL CONTRACEPTIVE PILLS

Acta Biomedica Scientifica, 2014
Magnesium is one of the important elements, necessary for the most of biochemical reactions, including those in nerve tissue. Magnesium insufficiency takes a leading position in the structure of elemental status pathology.
I. S. Vyatkina, L. V. Suturina, L. A. Grebenkina, M. A. Darenskaya, L. M. Lazareva   +4 more
doaj  

The regulatory effects of pyridoxine deficiency on the grass carp (Ctenopharyngodon idella) gill barriers immunity, apoptosis, antioxidant, and tight junction challenged with Flavobacterium columnar

, 2020
Xin Zheng, Lin Feng, Wei‐Dan Jiang, Pei Wu, Liu Yang, Sheng‐Yao Kuang, Ling Tang, Xiao‐Qiu Zhou   +7 more
openalex   +2 more sources

Identifying Immune Cells as Mediators in the Impact of Gut Microbiota on Congenital Malformations of the Nervous System

Brain and Behavior, Volume 16, Issue 1, January 2026.
This study reveals causal links between gut microbiota and congenital nervous system malformations, identifying nine immune cell types, such as CD20+ and CD25+ B cells, as mediators, highlighting gut–immune interactions as potential preventive or therapeutic targets.
Haokun Tian, Xiaolan Guo, Jialu Yu, Yuanfang Lu, Wensen Cao, Xiuwei Wang, Zhiqiang Zhu, Zhen Guan, Aiyun Yang, Shen Li, Xiaochun Xu, Caihua Wang, Jianhua Wang   +12 more
wiley   +1 more source

A Rare Clinical Manifestation of Disseminated Tuberculosis: Case Report of Tuberculous Meningitis With Flaccid Paralysis

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT This case highlights a rare presentation of disseminated tuberculosis in a child, manifesting as tuberculous meningitis and flaccid paralysis due to spinal tuberculosis. Timely initiation of antitubercular therapy, corticosteroids, and ventriculoperitoneal shunt placement led to full recovery, emphasizing tuberculosis consideration in atypical
Aisha Haleem, Saad Ashraf, Areeba Ahsan, Maria Qadri, Iqra shahid, Biruk Demisse Ayalew   +5 more
wiley   +1 more source

Biological Conversion of Formate to Organic Compounds: Toward a Sustainable Formate Bioeconomy

Carbon Energy, Volume 8, Issue 1, January 2026.
Formate bioconversion plays a crucial role in achieving renewable resource utilization and sustainable development. To tap its full potential, it is important to identify the most appropriate microbial hosts for incorporating formate into building blocks, design the most promising metabolic pathways for transmitting formate into central carbon ...
Jinyi Qian, Tiantian Chai, Chunlei Zhao, Xiulai Chen   +3 more
wiley   +1 more source