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Levodopa and Pyridoxine-Deficient States

JAMA: The Journal of the American Medical Association, 1970
To the Editor.— On theoretical grounds, extra attention should be paid to patients with Parkinson's disease being considered for levodopa therapy who also have conditions rendering them relatively pyridoxine deficient. Among the conditions associated with relative pyridoxine deficiencies are certain illnesses (diabetes mellitus, chronic alcoholism ...
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Tubuloreticular structures in pyridoxine deficiency

Experimental and Toxicologic Pathology, 1993
Electron microscopic studies on renal tissue obtained from animals subjected to pyridoxine deficiency have revealed the presence of round and/or tubular bodies in the cytoplasm of endothelial cells of the glomeruli. The bodies generally occur as aggregates in association with the endoplasmic reticulum. Along with the round forms other profiles are also
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Methionine Metabolism in Pyridoxine Deficiency

Annals of Nutrition and Metabolism, 1974
Methionine metabolism was studied in a group of subjects having clinical signs and symptoms of peripheral neuropathy. Following a load of methionine, these subjects excreted higher amounts of cystathionine, and the ratio of cystathionine/ cysteine sulfinic acid was elevated suggesting a block in the conversion of cystathionine to cysteine sulfinic acid.
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Rat Brain Glutathione and Pyridoxine Deficiency

Nature, 1959
DOUGLAS and Mortensen1 have shown that in vivo synthesis of glutathione from glycine occurs in rat brain. If this synthesis in brain is similar to that which is known to take place in liver then it would follow the general pattern described by Snoke and Bloch2.
M J, ASHWOOD-SMITH, A D, SMITH
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Electrocardiographic Changes Due to Pyridoxine Deficiency

Pacing and Clinical Electrophysiology, 2003
A young woman presented with marked alterations in the ECG without cardiological symptoms or evidence of structural heart disease after further evaluation. There was evidence of vitamin deficiency and the ECG normalized after 10 days of treatment with vitamins. Similar alterations have been described in several experimental studies with rats, but this
Eduardo, Malmierca   +2 more
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Pyridoxine-Deficiency Neuropathy Due to Hydralazine

New England Journal of Medicine, 1965
PARESTHESIA has been noted in 81 to 152 per cent of patients receiving the antihypertensive drug hydralazine (Apresoline); these symptoms of neuropathy persist and become more bothersome if the dose is not reduced. The possible role of pyridoxine (vitamin B6) deficiency in the pathogenesis of this problem is suggested by the fact that the hydrazine ...
N H, Raskin, R A, Fishman
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Dietary pyridoxine deficiency reduced growth performance and impaired intestinal immune function associated with TOR and NF‐&kgr;B signalling of young grass carp (Ctenopharyngodon idella)

Fish and Shellfish Immunology, 2017
Xin Zheng   +10 more
semanticscholar   +1 more source

Pyridoxine Deficiency

Archives of Internal Medicine, 1982
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Pyridoxine Deficiency in Baby Pigs

Journal of Animal Science, 1951
W P, LEHRER   +3 more
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Pyridoxine deficiency in adult patients with status epilepticus

Epilepsy & Behavior, 2015
Hina Dave   +4 more
semanticscholar   +1 more source

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