Results 51 to 60 of about 20,142 (302)
Advanced Science, EarlyView.Neural tube defects (NTDs) are among the most common congenital malformations. However, the underlying etiology and mechanism remain elusive. Here, the role of DNA double‐strand breaks (DSBs) in 3D genome organization within the NTDs with folate deficiency is reported.
Ting Zhang +12 more
wiley +1 more source
Advanced Science, EarlyView.BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang +9 more
wiley +1 more source
In-Vitro Phagocytosis In Pyridoxine Deficiency [PDF]
Journal of Medical Microbiology, 1971 Summary We detected subtle differences between the phagocytic activity of cells from pyridoxine-deficient and normal guinea-pigs by means of a suitable combination of parameters at two different cell-to-bacterium ratios. This difference was modest in amount, but statistically highly significant.
openaire +2 more sources
Animal Research and One Health, EarlyView.This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu +8 more
wiley +1 more source
Classical homocystinuria, is it safe to exercise?
Molecular Genetics and Metabolism Reports, 2021 BackgroundCystationine β-synthase (CBS) deficiency is a genetic disorder characterized by severe hyperhomocysteinemia and thrombotic complications. In healthy individuals, physical exercise may result in a transient increase in plasma total homocysteine (
Aurel T. Tankeu +7 more
doaj +1 more source
Biological Conversion of Formate to Organic Compounds: Toward a Sustainable Formate Bioeconomy
Carbon Energy, EarlyView.Formate bioconversion plays a crucial role in achieving renewable resource utilization and sustainable development. To tap its full potential, it is important to identify the most appropriate microbial hosts for incorporating formate into building blocks, design the most promising metabolic pathways for transmitting formate into central carbon ...
Jinyi Qian +3 more
wiley +1 more source
Effect of Preventive Supplementation with Zinc and other Micronutrients on Non-Malarial Morbidity in Tanzanian Pre-School Children: A Randomized Trial. [PDF]
, 2012 The efficacy of preventive zinc supplementation against diarrhea and respiratory illness may depend on simultaneous supplementation with other micronutrients.
Ayşe Y. Demir +10 more
core +8 more sources
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Erythropoiesis in Pyridoxine Deficient Mice
Experimental Biology and Medicine, 1974 SummaryMice maintained on a pyridoxine deficient diet developed a progressive anemia characterized by hypochromia, microcytosis, reticulocytosis, and erythroid hyperplasia of the marrow and spleen. Circulating siderocytes were greatly increased. Hypertransfusion of these animals with red cells obtained from pyridoxine deficient donors resulted in ...
M, Keyhani +3 more
openaire +2 more sources
Xanthurenic acid and its rôle in the trytophane metabolism of pyroxidine-deficient rats [PDF]
, 1943 In a previous publication (1) the isolation of a green pigment from the urine of pyridoxine-deficient rats was described. The green pigment was shown to be the product of a reaction between ferric ammonium sulfate or other ferric salts and a compound ...
Haagen-Smit, A. J. +2 more
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