Results 81 to 90 of about 20,142 (302)

Genetic risk factor identification for common epilepsies guided by integrative omics data analysis

Epilepsia, EarlyView.
Abstract Objective Genetic generalized epilepsies (GGEs) comprise the most common genetically determined epilepsy syndromes, following a complex mode of inheritance. Although many important common and rare genetic factors causing or contributing to these epilepsies have been identified in the past decades, many features of the genetic architecture are ...
Ashwini Mushunuri, Oluyomi Adesoji, Roland Krause, Patrick May, Holger Lerche, Albert Becker, Daniela Grimm, International League Against Epilepsy Consortium on Complex Epilepsies, Michael Nothnagel, Herbert Schulz   +9 more
wiley   +1 more source

High-Fidelity Simulation Scenario: Pyridoxine-Dependent Epilepsy and Treatment

MedEdPORTAL, 2018
Introduction Treatment of seizures in the neonatal patient is urgent and time sensitive. Effective and timely treatment of this life-threatening condition is vital in preventing mortality and long-term morbidity. This simulation-based curriculum involves
Jacob Anderson, Nathan Arboleda, Vincent Calleo   +2 more
doaj   +1 more source

Competition between binding partners of yeast Pex3 affects peroxisome biology

The FEBS Journal, EarlyView.
Pex3 is a peroxisomal membrane protein (PMP) that specifically recruits several binding partners. In the yeast Hansenula polymorpha, Atg30 (pexophagy), Inp1 (inheritance) and Pex19 (receptor for new PMPs) associate with Pex3. Overexpression of any of these proteins affects peroxisomal processes because these proteins compete for binding to Pex3.
Eline M. F. de Lange, Grzegorz Chojnowski, Jérôme Bürgi, Rifka Vlijm, Matthias Wilmanns, Ida J van der Klei   +5 more
wiley   +1 more source

Sugar and chromosome stability: Clastogenic effects of sugars in vitamin B6-deficient cells [PDF]

, 2014
Pyridoxal 5'-phosphate (PLP), the active form of vitamin B6, has been implicated in preventing human pathologies, such as diabetes and cancer. However, the mechanisms underlying the beneficial effects of PLP are still unclear. Using Drosophila as a model
Gatti, Maurizio, Marzio, Antonio, Merigliano, Chiara, Verni', Fiammetta   +3 more
core   +3 more sources

First attempt at using a synthetic diet in short‐lived killifish, a vertebrate model of ageing

Journal of Fish Biology, EarlyView.
Abstract Diet standardization of model organisms is crucial for experimental consistency and repeatability in laboratory research, yet laboratory fish often lack species‐specific, open‐formula standardized diets. This study aims to address this gap by testing the effect of macronutrient content on the performance of Nothobranchius furzeri, an ...
Jakub Žák, Milan Vrtílek
wiley   +1 more source

Influence of concentration on the radiolytic decomposition of thiamine, riboflavin, and pyridoxine in aqueous solution

Revista Colombiana de Química, 2014
Vitamin loss during irradiation has been claimed as a critical area in food irradiation technology, especially that of thiamine (B1), which has been considered as the most sensitive to radiation.
Guadalupe Albarrán, Edith Mendoza, Juan M. Beltrán   +2 more
doaj   +1 more source

EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2013. Scientific Opinion on nutrient requirements and dietary intakes of infants and young children in the European Union. [PDF]

, 2013
Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver a Scientific Opinion on the nutrient requirements and dietary intakes of infants and young ...
AAP Committee on Nutrition (American Academy of Paediatrics Committee on Nutrition), Abrams, Abumrad, Afssa (Agence française de sécurité sanitaire des aliments), Aggett, Aggett, Aggett, Agostoni, Agostoni, Alexy, Alexy, Alexy, Allen, Andersen, Andersen, Andersson, Antonakou, Arena Ansótegui, Arnberg, Ashley, Barker, Ben, Bettler, Birch, Bjørke‐Monsen, Bjørke‐Monsen, Black, Bonewald, Bouglé, Braegger, Bramhagen, Bramhagen, Brenna, Brenna, Brunser, Burdge, Butte, Butte, Butte, Böhles, Caballero, Caballero, Caballero, Caballero, Capozzi, Carriquiry, Casey, Challa, Cohen, Costalos, Costeira, Crawley, Crider, Cunnane, da Costa, Dahl, Daly, Davies, Dawodu, de Benoist, Decsi, Delange, Dituri, DoH (Department of Health), Domellöf, Domellöf, Domellöf, Domellöf, Dorea, Dror, Dube, Dube, Duggan, D‐A‐CH (Deutsche Gesellschaft für Ernährung ‐ Österreichische Gesellschaft für Ernährung ‐ Schweizerische Gesellschaft für Ernährungsforschung ‐ Schweizerische Vereinigung für Ernährung), EFSA (European Food Safety Authority), EFSA (European Food Safety Authority), EFSA (European Food Safety Authority), EFSA (European Food Safety Authority), EFSA (European Food Safety Authority), EFSA (European Food Safety Authority), EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition, and Allergies), EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition, and Allergies), EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition, and Allergies), EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition, and Allergies), EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition, and Allergies), EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition, and Allergies), Emmett, Engel, Engelmann, Fairweather‐Tait, Fairweather‐Tait, Fanaro, Fantino, Farquharson, Fischer, Fomon, Fomon, Fomon, Fomon, Freeman, Fuchs, Gallo, Gibson, Gill, Glaser, Gompakis, Gondolf, Grant, Grote, Gunnarsdottir, Gunnarsson, Gürgöze, Han, Harris, Harsløf, Hay, Hay, Hay, Hay, Henriksen, Henry, Hicks, Hilbig, Hintzpeter, Hoffman, Hoffman, Hopkins, Hopkins, Houghton, Houghton, Humphrey, Huybrechts, Ilcol, IoM, IoM (Institute of Medicine), IoM (Institute of Medicine), IoM (Institute of Medicine), IoM (Institute of Medicine), IoM (Institute of Medicine), IoM (Institute of Medicine), IoM (Institute of Medicine), IUNA (Irish Universities Nutrition Alliance), Jansson, Jensen, Jensen, Johnson, Jonsdottir, Karademir, Kersting, Kersting, Kersting, Knol, Koletzko, Koletzko, Koletzko, Krachler, Krebs, Krebs, Krebs, Krebs, Krebs, Kyttälä, Körner, Lagström, Lapinleimu, Lattka, Leotsinidis, Lind, Lucas, Lusk, Lynch, Lönnerdal, Lönnerdal, Madsen, Makrides, Maldonado Lozano, Male, Manios, Marriott, Marriott, Mayne, McNulty, Michaelsen, Michaelsen, Milne, Minns, Mičeti$cA‐Turk, Morley, Moro, Muntau, Navarro‐Blasco, Neville, Nielsen, Niinikoski, Nimptsch, Noble, Noble, Olafsdottir, Olausson, Owen, Pasternak, Piemontese, Pludowski, Pouessel, Powers, Prasad, Prentice, Rao, Reiss, Roberts, Rodriguez Rodriguez, Rogers, Räsanen, Sampaio, SCF (Scientific Committe for Food), SCF (Scientific Committee for Food), SCF (Scientific Committee for Food), SCF (Scientific Committee for Food), SCF (Scientific Committee for Food), SCF (Scientific Committee for Food), Scholtens, Schwartz, Schwartz, Sette, Sezer, Shils, Shils, Sichert‐Hellert, Sievers, Sioen, Soriguer, Stam, Stein, Stevens, Strambi, Szlagatys‐Sidorkiewicz, Szymlek‐Gay, Tanumihardjo, Tanumihardjo, Thamm, Thane, Thane, Thane, Thorisdottir, Thorisdottir, Thorisdottir, Thorisdottir, Thorsdottir, Thorsdottir, Tijerina‐Saenz, Toschke, Truong, Tuthill, Tympa‐Psirropoulou, Ulbak, Van Biervliet, Van Biervliet, Vendt, Virtanen, Vlaardingerbroek, von Kries, Wang, Wasowicz, WHO Secretariat, Andersson M, de Benoist B, Delange F and Zupan J, WHO/FAO (World Health Organization/Food and Agricultural Organization of the United Nations), WHO/FAO (World Health Organization/Food and Agriculture Organization of the United Nations), Williams, Wojcik, Zachara, Ziegler, Zimmermann, Öhlund, Özdemir, Özden, Østergård   +284 more
core   +1 more source

Effects of an Isoquinoline Alkaloids Blend on the Expression of Genes Relevant for Antioxidant Capacity, Barrier Integrity and Inflammation Along the Broiler Gut

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Intensive broiler production may lead to perturbations of gut function and health. The maintenance of intestinal homeostasis in broilers through the use of dietary phytogenic components such as isoquinoline alkaloids (IQs) is an emerging topic of scientific investigations.
Vasileios V. Paraskeuas, Ioannis Brouklogiannis, Anja Pastor, Konstantinos C. Mountzouris   +3 more
wiley   +1 more source

Substrate transport and drug interaction of human thiamine transporters SLC19A2/A3

Nature Communications
Thiamine and pyridoxine are essential B vitamins that serve as enzymatic cofactors in energy metabolism, protein and nucleic acid biosynthesis, and neurotransmitter production.
Peipei Li, Zhini Zhu, Yong Wang, Xuyuan Zhang, Chuanhui Yang, Yalan Zhu, Zixuan Zhou, Yulin Chao, Yonghui Long, Yina Gao, Songqing Liu, Liguo Zhang, Pu Gao, Qianhui Qu   +13 more
doaj   +1 more source

Comparison of the effectiveness of an oral combination of thiamine, pyridoxine, and cyanocobalamin with parenteral cyanocobalamin in adolescents with nutritional vitamin B12 deficiency

Gülhane Tıp Dergisi
Aims: Nutritional vitamin B12 deficiency remains a significant public health issue. This study aimed to compare the efficacy of an oral combination of thiamine, pyridoxine, cyanocobalamin, and parenteral cyanocobalamin treatment among adolescents with ...
Ömer Güneş, Mehmet Ağıllı, Fatih Üçkardeş, Yüksel Hakan Aydoğmuş, Bahar Öztelcan Gündüz, Erman Ataş   +5 more
doaj   +1 more source