Results 81 to 90 of about 908,246 (301)

Genetic risk factor identification for common epilepsies guided by integrative omics data analysis

Epilepsia, EarlyView.
Abstract Objective Genetic generalized epilepsies (GGEs) comprise the most common genetically determined epilepsy syndromes, following a complex mode of inheritance. Although many important common and rare genetic factors causing or contributing to these epilepsies have been identified in the past decades, many features of the genetic architecture are ...
Ashwini Mushunuri, Oluyomi Adesoji, Roland Krause, Patrick May, Holger Lerche, Albert Becker, Daniela Grimm, International League Against Epilepsy Consortium on Complex Epilepsies, Michael Nothnagel, Herbert Schulz   +9 more
wiley   +1 more source

Substrate transport and drug interaction of human thiamine transporters SLC19A2/A3

Nature Communications
Thiamine and pyridoxine are essential B vitamins that serve as enzymatic cofactors in energy metabolism, protein and nucleic acid biosynthesis, and neurotransmitter production.
Peipei Li, Zhini Zhu, Yong Wang, Xuyuan Zhang, Chuanhui Yang, Yalan Zhu, Zixuan Zhou, Yulin Chao, Yonghui Long, Yina Gao, Songqing Liu, Liguo Zhang, Pu Gao, Qianhui Qu   +13 more
doaj   +1 more source

Radiomanganese Studies in Pyridoxine Deficient Rats

Experimental Biology and Medicine, 1962
SummaryTissue distribution and excretion of radioactivity following intravenous injection of Mn54Cl2 at 3 different time intervals were studied in rats deficient in pyridoxine and in control animals. The findings indicate that deficiency of pyridoxine is associated with increased uptake of the injected dose by brain and testicles, and with decreased ...
J M, HSU, B, KAWIN
openaire   +2 more sources

First attempt at using a synthetic diet in short‐lived killifish, a vertebrate model of ageing

Journal of Fish Biology, EarlyView.
Abstract Diet standardization of model organisms is crucial for experimental consistency and repeatability in laboratory research, yet laboratory fish often lack species‐specific, open‐formula standardized diets. This study aims to address this gap by testing the effect of macronutrient content on the performance of Nothobranchius furzeri, an ...
Jakub Žák, Milan Vrtílek
wiley   +1 more source

Influence of concentration on the radiolytic decomposition of thiamine, riboflavin, and pyridoxine in aqueous solution

Revista Colombiana de Química, 2014
Vitamin loss during irradiation has been claimed as a critical area in food irradiation technology, especially that of thiamine (B1), which has been considered as the most sensitive to radiation.
Guadalupe Albarrán, Edith Mendoza, Juan M. Beltrán   +2 more
doaj   +1 more source

Isolated Pyridoxine Deficiency Presenting as Peripheral Neuropathy Post-chemotherapy. [PDF]

Cureus, 2022
Sawhney A, Singhal S, Patel R.
europepmc   +1 more source

Trajectories of Dietary Energy, Macro and Micronutrient Intake From the Third Trimester of Pregnancy to 8.5 Months Postpartum Among Brazilian Women: The Mothers, Infants and Lactation Quality Study

Maternal &Child Nutrition, EarlyView.
The trajectories of energy, macro, and micronutrient intake from pregnancy to 8.5 months postpartum showed a stability in energy and protein, a decline in carbohydrates and fibre, and discrete increases in total fat, mono, poly, and saturated fat. In addition, there was a decline in the intake of most micronutrients.
Aline Yukari Kurihayashi, Bruna Celestino Schneider, Amanda Caroline Cunha Figueiredo, Gabriela Torres Silva, Adriana Divina de Souza Campos, Daniela Polessa Paula, Daniela de Barros Mucci, Lindsay H. Allen, Gilberto Kac   +8 more
wiley   +1 more source

Genotypic Spectrum in a Cohort of Sri Lankan Patients With Homocystinuria

JIMD Reports
Homocystinuria due to cystathionine beta‐synthase (CBS) deficiency is a rare metabolic disorder inherited as an autosomal recessive trait. Spectrum of genetic variants in CBS gene and their correlation with the phenotypes of homocystinuria in Sri Lankan ...
Hewa Warawitage Dilanthi, Kandana Liyanage Subhashinie Jayasena, Nambage Dona Priyani Dhammika, Neluwa Liyanage Ruwan Indika, Matara Mahavidanage Nishani De Silva, Imalke Kankananarachchi, Pushpa Malkanthi Gardiye Punchihewa, Dharma Irugalbandara, Sabine Schroeder, Kosala Karunaratne, Eresha Jasinge   +10 more
doaj   +1 more source

Deciphering the biosynthetic pathways of lichen acids

New Phytologist, EarlyView.
Summary Depsides and depsidones are polyketide‐derived lichen acids widely distributed in lichen thalli, yet the biosynthetic gene clusters (BGCs) responsible for their production remain poorly understood. To address this gap, we investigated the diversity and evolutionary relationships of polyketide BGCs in lichens.
Wonyong Kim, Tânia Keiko Shishido, Huong T. Pham, Kyo Bin Kang, Rundong Liu, Matti Wahlsten, Jérôme Collemare, Hyun Park, Soon‐Ok Oh, Hyung‐Ho Ha, Hangun Kim, Jae‐Seoun Hur   +11 more
wiley   +1 more source

Identification of a novel link connecting indole‐3‐acetamide with abscisic acid biosynthesis and signaling

New Phytologist, EarlyView.
Summary Plants orchestrate their developmental processes and responses to environmental stimuli through a sophisticated network of small signaling molecules, termed phytohormones. Among these, auxins are recognized for their role in promoting plant growth.
José Moya‐Cuevas, Paloma Ortiz‐García, Adrián González Ortega‐Villaizán, Irene Viguera‐Leza, Andrés Pérez‐González, Javier Paz‐Ares, Carlos Alonso‐Blanco, Jesús Vicente‐Carbajosa, Stephan Pollmann   +8 more
wiley   +1 more source