BackgroundAlthough tremendous success has been achieved in the development and deployment of effective COVID-19 vaccines, developing effective therapeutics for the treatment of those who do come down with the disease has been with limited success.
Shaibu Oricha Bello +24 more
doaj +1 more source
Mutations in PROSC Disrupt Cellular Pyridoxal Phosphate Homeostasis and Cause Vitamin B6-Dependent Epilepsy [PDF]
Pyridoxal 5'-phosphate (PLP), the active form of vitamin B6, functions as a cofactor in humans for more than 140 enzymes, many of which are involved in neurotransmitter synthesis and degradation.
Champion, Mike +19 more
core +1 more source
Suggested Study as a Treatment Protocol for Coronavirus
Coronaviruses are a large family of RNA viruses without segment, positive-sense RNA genomes and single-stranded, which cause illnesses. The disease ranging from mild in most people to diseases that is more dangerous.
Shahin, M. I
doaj +1 more source
Pyridoxine Supplementation Improves the Activity of Recombinant Glutamate Decarboxylase and the Enzymatic Production of Gama-Aminobutyric Acid. [PDF]
Glutamate decarboxylase (GAD) catalyzes the irreversible decarboxylation of L-glutamate to the valuable food supplement γ-aminobutyric acid (GABA).
Yan Huang, Lingqia Su, Jing Wu
doaj +1 more source
Enzymes as Feed Additive to Aid in Responses Against Eimeria Species in Coccidia-Vaccinated Broilers Fed Corn-Soybean Meal Diets with Different Protein Levels [PDF]
This research aimed to evaluate the effects of adding a combination of exogenous enzymes to starter diets varying in protein content and fed to broilers vaccinated at day of hatch with live oocysts and then challenged with mixed Eimeria spp. Five hundred
Clack, Beatrice A. +8 more
core +2 more sources
Dynamic Metabolic Footprinting Reveals the Key Components of Metabolic Network in Yeast Saccharomyces cerevisiae [PDF]
Metabolic footprinting offers a relatively easy approach to exploit the potentials of metabolomics for phenotypic characterization of microbial cells.
Chumnanpuen, Pramote +3 more
core +3 more sources
Certification of the Mass Fractions of Vitamins in Whole Milk Powder - Certified Reference Material ERM®-BD600 [PDF]
This report describes the production of the reference material ERM-BD600, a whole milk powder certified for the mass fractions of water- and fat-soluble vitamins.
DABRIO RAMOS Marta +2 more
core +1 more source
Thiamin, riboflavin, pyridoxine and niacin requirements of growing Japanese quail fed purified diets [PDF]
Growing Japanese quail at 35 days of the experiment, weighed respectively, as follows when fed the various levels of a test vitamin in their diet: (a) thiamin hydrochloride (mg/kg diet), 1, 1.5, 2, 2.5, 3, and 3.5; body weight (g), 68.5, 94.8, 105.7, 103.
Mak, T. K., Vohra, Pran
core
Competition between binding partners of yeast Pex3 affects peroxisome biology
Pex3 is a peroxisomal membrane protein (PMP) that specifically recruits several binding partners. In the yeast Hansenula polymorpha, Atg30 (pexophagy), Inp1 (inheritance) and Pex19 (receptor for new PMPs) associate with Pex3. Overexpression of any of these proteins affects peroxisomal processes because these proteins compete for binding to Pex3.
Eline M. F. de Lange +5 more
wiley +1 more source
ABSTRACT Chronic kidney disease (CKD) is a known risk factor for hypercalcemia in cats. Phosphate‐restricted diets have also been implicated in causing hypercalcemia, in part because phosphate restriction increases the Ca:P ratio. The primary objective of this study was to evaluate the impact of two different therapeutic renal foods on ionized (iCa ...
Jean A. Hall +4 more
wiley +1 more source

