Results 71 to 80 of about 142,362 (228)

CSE‐Derived Hydrogen Sulfide Safeguards Vascular Iron Homeostasis by Coupling Ferritin Buffering to Vasoprotection

The FASEB Journal, Volume 39, Issue 20, 31 October 2025.
With iron overload, wild‐type (CSE+/+) mice upregulate their CSE and ferritin expression, limiting oxidative stress and maintaining vascular health. In contrast, CSE‐deficient (CSE−/−) mice fail to induce ferritin, leading to elevated oxidative stress, vascular remodeling, and hypertension.
Hassan Mustafa Arif, Ming Fu, Richa Verma, Rui Wang   +3 more
wiley   +1 more source

Identifying Gene Predictors of Chemicals Linked With Breast Cancer: A Machine Learning Analysis of MCF7 Cellular Transcriptomic Screening Data

Environmental and Molecular Mutagenesis, Volume 66, Issue 8, Page 425-441, October 2025.
ABSTRACT Breast cancer is the most prevalent cancer in women and has been linked to exposure to environmental chemicals. However, many chemicals have not been evaluated for relationships with this outcome. In this study, we analyzed RNA sequencing data from human breast cancer‐derived MCF7 cells exposed to hundreds of individual chemicals.
Lauren E. Koval, Richard Judson, Julia E. Rager   +2 more
wiley   +1 more source

Herbal Medicines for Weight Loss and Lipid Profile Improvement: A Scoping Review of Therapeutic Effects and Safety

Phytotherapy Research, Volume 39, Issue 10, Page 4870-4912, October 2025.
ABSTRACT The demand for alternative weight loss therapies has surged, with herbal medicinal products gaining popularity due to their natural origins, perceived safety, and accessibility. However, evidence regarding their therapeutic effects and safety for weight loss remains limited.
Marcela Forgerini, Geovana Schiavo, Osvaldo Galo Neto, Gabriela Barbosa Nascimento, Johnny Wallef Leite Martins, Patrícia de Carvalho Mastroianni   +5 more
wiley   +1 more source

Examination of CORN‐fermented protein and high protein distillers dried grains to replace fish meal and poultry meal in juvenile rainbow trout diets

Journal of the World Aquaculture Society, Volume 56, Issue 5, October 2025.
Abstract The ability of high‐value plant protein concentrates to replace fish meal and other expensive animal proteins in diets for rainbow trout depends on their available nutrient composition, cost and consistency. The aim of this study was to assess the effects of two novel corn protein products (ANDVantage™ 40Y and ANDVantage™ 50Y, The Andersons ...
Wendy M. Sealey, Abigail Bockus, Scott Tilton, T. Gibson Gaylord   +3 more
wiley   +1 more source

Exploring the Effects of Artemisia absinthium L. Essential Oil on Pseudopregnancy Model in Rats

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
This study investigated the therapeutic effects of Artemisia absinthium essential oil in a rat model of pseudopregnancy. Oral administration of the essential oil, particularly at 25 mg/kg, significantly alleviated pseudopregnancy symptoms, demonstrating comparable efficacy to bromocriptine.
Mürşide Ayşe Demirel, İpek Süntar, Ali Osman Çeribaşı, Kevser Taban, Gökhan Zengin   +4 more
wiley   +1 more source

Evaluation of Phaseolus vulgaris lec‐ lpa as Alternative Protein Source on Growth Performances, Health Status, Faecal Minerals and Gut Microbiota in Weaned Piglet's Diet

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
Partial replacement of soybean meal with an innovative Phaseolus vulgaris genotype with low lectin and phytic acid content was evaluated in weaned pigs’ diet. Although piglets fed the bean‐based diet showed reduced growth performance, their health status was preserved, registering lower faecal mineral excretion, suggesting reduced environmental ...
Benedetta Canala, Sara Frazzini, Matteo Dell'Anno, Matteo Santoru, Irene Ferri, Francesca Sparvoli, Lucrezia Luciani, Bianca Castiglioni, Paola Cremonesi, Filippo Biscarini, Martina Ghidoli, Roberto Pilu, Luciana Rossi   +12 more
wiley   +1 more source

Use of 5% Topical Minoxidil Application for Telogen Effluvium: An Open‐Label Single‐Arm Clinical Trial

The Journal of Dermatology, Volume 52, Issue 9, Page 1351-1359, September 2025.
ABSTRACT Telogen effluvium (TE) is an acute and diffuse hair loss due to an abnormal increase in telogen hair follicles in response to external or internal factors. Recently, TE attracts global interest as a major cause of hair loss as a sequela of COVID‐19.
Manabu Ohyama, Ryokichi Irisawa, Masaki Uchiyama, Miho Mori, Kazuhiro Aoki, Yuto Ueda, Toru Fujita   +6 more
wiley   +1 more source

First‐in‐class inhibitors of SbnA reduce siderophore production in Staphylococcus aureus

The FEBS Journal, Volume 292, Issue 17, Page 4650-4674, September 2025.
The production of the iron‐chelating compound staphyloferrin B by the most invasive S. aureus strains is crucial for colonization, virulence, and survival in the host. Staphyloferrin B biosynthesis is carried out by eight enzymes, the Sbn system, that offer an appealing source of potential targets for the development of antimicrobials.
Sarah Hijazi, Monica Cozzi, Somayeh Asgharpour, Omar De Bei, Serena Faggiano, Francesco Marchesani, Luca Ronda, Marialaura Marchetti, Eleonora Gianquinto, Mariacristina Failla, Gauthier Trèves, Loretta Lazzarato, Francesca Spyrakis, Barbara Campanini, Emanuela Frangipani, Stefano Bettati   +15 more
wiley   +1 more source

The CRISPR‐Cas9 knockout DDC SH‐SY5Y in vitro model for AADC deficiency provides insight into the pathogenicity of R347Q and L353P variants: a cross‐sectional structural and functional analysis

The FEBS Journal, Volume 292, Issue 18, Page 4833-4853, September 2025.
Here, we generated a DDC‐KO cellular model for studying aromatic amino acid decarboxylase (AADC) deficiency. This model was created using CRISPR‐Cas9 in the SH‐SY5Y neuroblastoma cell line and was validated through the absence of the dopamine product and an altered l‐dopa metabolite profile.
Cristian Andres Carmona‐Carmona, Giovanni Bisello, Rossella Franchini, Gianluigi Lunardi, Roberta Galavotti, Massimiliano Perduca, Rui P. Ribeiro, Benny Danilo Belviso, Alejandro Giorgetti, Rocco Caliandro, Patricia M.‐J. Lievens, Mariarita Bertoldi   +11 more
wiley   +1 more source

Determination of Vitamin B6 (pyridoxine hydrochloride) in Pharmaceutical Preparations Using High Performance Liquid Chromatography

Iraqi Journal of Science, 2019
Determination of vitamin B6 (pyridoxine hydrochloride) was described using high performance liquid chromatographic method. The analysis was achieved by cosmos IL 5C18-MS-II column (250 mm x 4.6 mm i. d., 5µm particle size) at room temperature.
H. Mahmood, R. Ahmad
semanticscholar   +1 more source