Results 11 to 20 of about 14,669 (203)
Perspectives on Cyclobutane Pyrimidine Dimers—Rise of the Dark Dimers† [PDF]
Photochemistry and Photobiology, 2021 ABSTRACTSome early reports demonstrate that levels of cyclobutane pyrimidine dimers (CPD) may increase after UVR exposure had ended, although these observations were treated as artifacts. More recently, it has been shown unequivocally that CPD formation does occur post‐irradiation, with maximal levels occurring after about 2–3 h.
Karl Lawrence +4 more
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The compost metagenome as a source of T4 bacteriophage pyrimidine dimer glycosylase homologues [PDF]
E3S Web of Conferences, 2021 Compost is a promising source of thermotolerant enzymes for their application in biotechnology. Homologues of bacteriophage T4 DNA glycosylase can find their application in pharmaceuticals and perfumery.
Karmanova Alexandra N. +2 more
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Photolyase Production and Current Applications: A Review
Molecules, 2022 The photolyase family consists of flavoproteins with enzyme activity able to repair ultraviolet light radiation damage by photoreactivation. DNA damage by the formation of a cyclobutane pyrimidine dimer (CPD) and a pyrimidine-pyrimidone (6-4 ...
Diana Ramírez-Gamboa +12 more
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The Class III Cyclobutane Pyrimidine Dimer Photolyase Structure Reveals a New Antenna Chromophore Binding Site and Alternative Photoreduction Pathways [PDF]
J Biol Chem, 2015 Patrick Scheerer +6 more
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Recombination between homologous chromosomes induced by unrepaired UV-generated DNA damage requires Mus81p and is suppressed by Mms2p. [PDF]
PLoS Genetics, 2015 DNA lesions caused by UV radiation are highly recombinogenic. In wild-type cells, the recombinogenic effect of UV partially reflects the processing of UV-induced pyrimidine dimers into DNA gaps or breaks by the enzymes of the nucleotide excision repair ...
Yi Yin, Thomas D Petes
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DNA backbone conformation in cis–syn pyrimidine[]pyrimidine cyclobutane dimers [PDF]
Biopolymers, 1980 A theoretical calculation involving minimization of energy functions was made to determine the conformation of a deoxydinucleoside monophosphate pyrimidine[ ]pyrimidine cis-syn cyclobutane dimer. Such single-stranded moieties are useful models for the in uiuo situation because single strands are more easily damaged, and the damage inhibits the normal ...
Suse Broyde +2 more
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Acta Dermato-Venereologica, 2020 DNA damage and oxidative stress play a critical role in photoageing. Seborrhoeic keratosis (SK) affects sunlight-exposed sites in aged individuals. This study examined the mechanism of photoageing in SK.
Kyung Ah Cheong, Ai-Young Lee
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Methyl 2-[2-(benzyloxycarbonylamino)propan-2-yl]-5-hydroxy-6-methoxypyrimidine-4-carboxylate
Acta Crystallographica Section E, 2011 In the title compound, C18H21N3O6, a pyrimidine derivative, the dihedral angle between the benzene and pyrimidine rings is 52.26 (12)°.
Hoong-Kun Fun +4 more
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IUCrJ, 2018 Cyclobutane pyrimidine dimer (CPD) photolyases harness the energy of blue light to repair UV-induced DNA CPDs. Upon binding, CPD photolyases cause the photodamage to flip out of the duplex DNA and into the catalytic site of the enzyme.
Manuel Maestre-Reyna +5 more
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