Results 21 to 30 of about 14,669 (203)
UVA Generates Pyrimidine Dimers In DNA Directly [PDF]
Biophysical Journal, 2009 There is increasing evidence that UVA radiation, which makes up approximately 95% of the solar UV light reaching the Earth's surface and is also commonly used for cosmetic purposes, is genotoxic. However, in contrast to UVC and UVB, the mechanisms by which UVA produces various DNA lesions are still unclear.
Jiang, Yong +7 more
openaire +3 more sources
6-Ethyl-5-fluoro-2-methoxypyrimidin-4(3H)-one
Acta Crystallographica Section E, 2009 In the title compound, C7H9FN2O2, the methoxy and ethyl groups form dihedral angles of 1.4 (2) and 73.5 (3)°, respectively, with the mean plane of the pyrimidine ring.
Yu-Yuan Ye, Kai Yang
doaj +1 more source
Taq DNA polymerase blockage at pyrimidine dimers [PDF]
Nucleic Acids Research, 1996 Nucleic Acids Research, 24 (8)
Wellinger, Ralf-Erik, Thoma, Fritz
openaire +4 more sources
1-[(Cyclopropylmethoxy)methyl]-5-ethyl-6-(4-methylbenzyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
Acta Crystallographica Section E, 2012 The pyrimidine ring in the title compound, C19H24N2O3, is nearly planar (r.m.s. deviation = 0.008 Å); the C atom at the 5-position deviates by 0.054 (3) Å from the mean plane and the C atom at the 6 ...
Nasser R. El-Brollosy +3 more
doaj +1 more source
Frontiers in Immunology, 2022 Ultraviolet (UV) radiation is one of the most genotoxic, universal agents present in the environment. UVB (280-315 nm) radiation directly damages DNA, producing cyclobutane pyrimidine dimers (CPDs) and pyrimidine 6-4 pyrimidone photoproducts (6-4PPs ...
Gustavo S. Kajitani +11 more
doaj +1 more source
6-(Trifluoromethyl)pyrimidine-2,4(1H,3H)-dione monohydrate
Acta Crystallographica Section E, 2010 The title compound, C5H3F3N2O2·H2O, was prepared by the reaction of ethyl 4,4,4-trifluoro-3-oxobutanoate with urea. In the crystal, the 6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione and water molecules are linked by N—H...O and O&#
Gong-Chun Li +3 more
doaj +1 more source
3-{[4-(4-Pyridyl)pyrimidin-2-yl]sulfanylmethyl}benzoic acid
Acta Crystallographica Section E, 2008 The title compound, C17H13N3O2S, was prepared by reaction of 4-(4-pyridyl)pyrimidine-2-thiol with 3-(bromomethyl)benzoic acid under basic conditions. Each pair of molecules is mutually linked via O—H...N hydrogen bonds, forming a dimer. The packing
Jun-Feng Ji, Hai Wang, Hai-Bin Zhu
doaj +1 more source
6-Chloro-N4,N4-dimethylpyrimidine-2,4-diamine
Acta Crystallographica Section E, 2012 The asymmetric unit of the title compound, C6H9ClN4, contains four independent molecules (A, B, C and D). Their main difference is the torsion angles, ranging from 1.6 (5) to 5.9 (5)°, between the methyl group and the ...
Bin Sun +3 more
doaj +1 more source
2-(4-Bromophenyl)-2-methyl-2,3-dihydroquinazolin-4(1H)-one
Acta Crystallographica Section E, 2010 In the title compound, C15H13BrN2O, the pyrimidine ring adopts a skew boat conformation. The amino H atom forms an intermolecular hydrogen bond with the carbonyl O atom of an adjacent molecule, forming an inversion dimer.
Mei-Mei Zhang, Ke Yang, Xiang-Shan Wang
doaj +1 more source
6-(3,5-Dimethylbenzyl)-5-ethyl-1-[(3-phenylpropoxy)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
Acta Crystallographica Section E, 2012 The pyrimidine ring of the title compound, C25H30N2O3, is approximately planar (r.m.s. deviation = 0.003 Å); the C atom at the 5-position deviates by 0.012 (3) Å from the mean plane and the C atom at the 6 ...
Nasser R. El-Brollosy +3 more
doaj +1 more source