Results 41 to 50 of about 14,669 (203)
6-(3,5-Dimethylbenzyl)-5-ethyl-1-[(2-phenylethoxy)methyl]pyrimidine-2,4(1H,3H)dione
Acta Crystallographica Section E, 2012 In the title pyrimidine derivative, C24H28N2O3, the uracil unit is essentially planar with an r.m.s. deviation of 0.0054 (1) Å for the eight non-H atoms. The pyrimidine ring is tilted by a dihedral angle of 77.08 (7)
Nasser R. El-Brollosy +4 more
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FEBS Open Bio, 2021 DNA damage removal by nucleotide excision repair (NER) and replicative bypass via translesion synthesis (TLS) and template switch (TSw) are important in ensuring genome stability.
Zoltán Szeltner +4 more
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Ethyl 2-(2,6-difluorobenzyloxy)-4-(4,6-dimethoxypyrimidin-2-yl)quinoline-3-carboxylate
Acta Crystallographica Section E, 2009 In the title compound, C25H21F2N3O5, the pyrimidine and difluorobenzyloxy rings are twisted away from the central quinoline ring system, making dihedral angles of 54.6 (1) and 74.1 (1)°, respectively. A weak C—H...O
Yuan-xiang Li
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N-Butyl-4,6-diphenylpyrimidin-2-amine
Acta Crystallographica Section E, 2011 In the title compound, C20H21N3, the pyrimidine ring is inclined at dihedral angles of 51.57 (4) and 2.49 (4)° to the two phenyl rings. The dihedral angle between the two terminal phenyl rings is 50.44 (4)°.
Hoong-Kun Fun +3 more
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Acta Crystallographica Section E, 2012 The asymmetric unit of the compound, C20H26N2O5·0.5C2H5OH, consists of two tetrahydropyrimidine-2,4-dione molecules and an ethanol molecule. The pyrimidine rings are nearly planar (r.m.s.
Nasser R. El-Brollosy +3 more
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Journal of Nucleic Acids, 2010 Escherichia coli DNA photolyase is an enzyme that repairs the major kind of UV-induced lesions, cyclobutane pyrimidine dimer (CPD) in DNA utilizing 350–450 nm light as energy source.
Lei Xu, Guoping Zhu
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Nature Communications, 2023 Decades ago, it was shown that proteins binding to DNA can quantitatively alter the formation of DNA damage by UV light. This established the principle of UV footprinting for non-intrusive study of protein-DNA contacts in living cells, albeit at limited ...
Kerryn Elliott +3 more
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Pyrimidine Dimers Block Simian Virus 40 Replication Forks [PDF]
Molecular and Cellular Biology, 1986 UV light produces lesions, predominantly pyrimidine dimers, which inhibit DNA replication in mammalian cells. The mechanism of inhibition is controversial: is synthesis of a daughter strand halted at a lesion while the replication fork moves on and reinitiates downstream, or is fork progression itself blocked for some time at the site of a lesion?
C A, Berger, H J, Edenberg
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2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidin-1-ium 2-propanamidobenzoate
Acta Crystallographica Section E, 2011 In the title salt, C12H14ClN4+·C10H10NO3−, zwitterionic N—H...O interactions form an R22(8) ring. The crystal structure is stabilized by N—H...O and N—H...N hydrogen bonds involving two different eight ...
Rita Mathews, Sampath Natarajan
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Replication of cyclobutane pyrimidine dimer analogue by Ex Taq DNA polymerase
Science and Technology of Advanced Materials, 2007 We previously reported an efficient and reversible template-directed photoligation using 5-carboxyvinyl-2'-deoxyuridine (CVU)-containing ODN at the 5'-terminal.
Masayuki Ogino et al
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