Influence of a pre-stimulation with chronic low-dose UVB on stress response mechanisms in human skin fibroblasts. [PDF]
PLoS ONE, 2017 Exposure to solar ultraviolet type B (UVB), through the induction of cyclobutane pyrimidine dimer (CPD), is the major risk factor for cutaneous cancer. Cells respond to UV-induced CPD by triggering the DNA damage response (DDR) responsible for signaling ...
Marie-Catherine Drigeard Desgarnier +3 more
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Effects of DNA looping on pyrimidine dimer formation [PDF]
Nucleic Acids Research, 1992 We have assessed the effects of DNA curvature on pyrimidine dimer (PD) formation by examining the pattern of PD formation in DNA held in a loop by lambda repressor. The loop region was composed of diverse DNA sequences such that potential PD sites occurred throughout the loop.
J R, Pehrson, L H, Cohen
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Investigation of structure and vibrational properties of cyclobutane pirimidine dimer [PDF]
Hemijska Industrija, 2013 We performed a theoretical analysis of the structure and vibrational properties of cyclobutane pyrimidine dimer, which is the main product in a photochemical reaction involving two molecules of 1-methylthymine.
Petković Milena M. +2 more
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1,3,7-Trimethyl-2,4-dioxo-1,2,3,4-tetrahydropteridine-6-carboxylic acid hemihydrate
Acta Crystallographica Section E, 2010 In the title compound, C10H10N4O4·0.5H2O, the two rings of the pteridine system are nearly coplanar [dihedral angle = 4.25 (9)°]. The atoms of the carboxyl group are also coplanar with the pteridine unit [r.m.s. deviation from
Miguel N. Moreno-Carretero +4 more
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PLoS Genetics, 2022 Ultraviolet light causes DNA lesions that are removed by nucleotide excision repair (NER). The efficiency of NER is conditional to transcription and chromatin structure. UV induced photoproducts are repaired faster in the gene transcribed strands than in
Laetitia Guintini +5 more
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Blocking cyclobutane pyrimidine dimer formation by steric hindrance [PDF]
Organic & Biomolecular Chemistry, 2016 Replacement of the C5 thymine methyl group with a bulky tert-butyl substituent completely blocks the formation of CPDs.
Vendrell Criado, Victoria +4 more
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N-(4-Methoxyphenyl)-6-methyl-2-phenyl-5-{[4-(trifluoromethyl)anilino]methyl}pyrimidin-4-amine
Acta Crystallographica Section E, 2013 The title compound, C26H23F3N4O, crystallizes with two symmetry-independent molecules in the asymmetric unit, denoted A and B, which differ mainly in the rotation of the methoxyphenyl ring.
Tadeusz Lis +3 more
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2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidin-1-ium 2-acetamidobenzoate
Acta Crystallographica Section E, 2011 The title compound, C12H14ClN4+·C9H8NO3−, is a salt with a 1:1 ratio of cation and anion components interacting with each other forming an R22(8) ring motif.
Sampath Natarajan, Rita Mathews
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Synthesis of Triazolyl Derivatives Based on Thiazolo[3,2-a]pyrimidine Propargyl Ethers
Chemistry ProceedingsThis work is devoted to the synthesis of triazolyl derivatives based on propargyl ethers of the thiazolo[3,2-a]pyrimidine series by [3+2]-cycloaddition and the study of their structure in solution and crystalline phase. The formation of homochiral chains
Elina Gabitova +8 more
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White collar 1‐induced photolyase expression contributes to UV‐tolerance of Ustilago maydis
MicrobiologyOpen, 2016 Ustilago maydis is a phytopathogenic fungus causing corn smut disease. It also is known for its extreme tolerance to UV‐ and ionizing radiation. It has not been elucidated whether light‐sensing proteins, and in particular photolyases play a role in its ...
Annika Brych +7 more
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