Results 91 to 100 of about 42,575 (244)

Role of a "Magic" Methyl: 2'-Deoxy-2'-α-F-2'-β-C-methyl Pyrimidine Nucleotides Modulate RNA Interference Activity through Synergy with 5'-Phosphate Mimics and Mitigation of Off-Target Effects. [PDF]

J Am Chem Soc, 2022
Guenther DC, Mori S, Matsuda S, Gilbert JA, Willoughby JLS, Hyde S, Bisbe A, Jiang Y, Agarwal S, Madaoui M, Janas MM, Charisse K, Maier MA, Egli M, Manoharan M.   +14 more
europepmc   +1 more source

Purine and pyrimidine nucleotide synthesis and degradation during in vitro morphogenesis of white spruce (Picea Glauca) [PDF]

, 2004
Claudio Stasolla
openalex   +1 more source

Heterologous plastoquinone production using a newly identified O2‐dependent cyanobacterial hydroxylase

The FEBS Journal, EarlyView.
In this study, we confirm that PlqH is the hydroxylase operating in plastoquinone biosynthesis in photosynthetic cyanobacteria (Cyanobacteriia). Our phylogenetic analyses demonstrate that cyanobacterial PlqH homologues originated from hydroxylases involved in ubiquinone biosynthesis in bacteria. Plastoquinone production in Escherichia coli was achieved
Morgane Roger‐Margueritat, Margot Beltran, Juliette Schnoebelen, Laura Flandrin, Wafa Rezali, Eline Michel, Sophie S. Abby, Fabien Pierrel   +7 more
wiley   +1 more source

Plant organelle C‐to‐U RNA editing factors can operate successfully in yeast (Saccharomyces cerevisiae) as an easily amenable eukaryotic system for their functional analysis

The FEBS Journal, EarlyView.
Plant‐type pentatricopeptide repeat proteins capable of C‐to‐U RNA editing perform faithfully when expressed in a new heterologous system, the yeast Saccharomyces cerevisiae. They were tested with constitutive and inducible expression and with a set of different solubility tags. PPR56, PPR65, and PPR78 from P.
Shyam Ramanathan, Annika Hanraths, Jingchan Xie, Mareike Schallenberg‐Rüdinger, Volker Knoop   +4 more
wiley   +1 more source

Harnessing S. cerevisiae to advance the engineering of pentatricopeptide repeat proteins

The FEBS Journal, EarlyView.
Heterologous expression systems have been instrumental in furthering our understanding of plant RNA editing proteins. In this commentary, we discuss how the establishment of yeast as a model for studying plant RNA editing by Ramanathan et al. could advance the engineering of pentatricopeptide repeat proteins, and how in return pentatricopeptide repeat ...
Farley M. Kwok van der Giezen, Ian Small
wiley   +1 more source

Plasma membrane-located purine nucleotide transport proteins are key components for host exploitation by microsporidian intracellular parasites.

PLoS Pathogens, 2014
Microsporidia are obligate intracellular parasites of most animal groups including humans, but despite their significant economic and medical importance there are major gaps in our understanding of how they exploit infected host cells.
Eva Heinz, Christian Hacker, Paul Dean, John Mifsud, Alina V Goldberg, Tom A Williams, Sirintra Nakjang, Alison Gregory, Robert P Hirt, John M Lucocq, Edmund R S Kunji, T Martin Embley   +11 more
doaj   +1 more source

Multi‐Omics Signatures of Periodontitis and Periodontal Therapy on the Oral and Gut Microbiome

Journal of Periodontal Research, EarlyView.
This multi‐omics study integrates shotgun metagenomics and NMR metabolomics to reveal coordinated microbial and metabolic signatures of periodontitis across the oral–gut axis. Non‐surgical periodontal therapy partially restored ecological and functional balance, supporting oral health as a modifiable driver of systemic microbial homeostasis.
Giacomo Baima, Shareef Dabdoub, Vivek Thumbigere‐Math, Davide Giuseppe Ribaldone, Gian Paolo Caviglia, Leonardo Tenori, Linda Fantato, Alessia Vignoli, Mario Romandini, Ilario Ferrocino, Mario Aimetti   +10 more
wiley   +1 more source

Removal of cyclobutane pyrimidine dimers by the UV damage repair and nucleotide excision repair pathways of Schizosaccharomyces pombe at nucleotide resolution [PDF]

, 1999
Marcel Lombaerts
openalex   +1 more source

ZmTH1 Is Vital for Healthy Plant Growth and Promotes Cold/Drought Tolerance by Regulating Thiamin Diphosphate‐Dependent Metabolisms in Maize

Plant Biotechnology Journal, EarlyView.
ABSTRACT Vitamin B1 (VB1) plays a crucial role in sustaining plant health and enabling adaptive responses to environmental stress. The complex maize genome implies a sophisticated VB1 synthesis pathway, with the mechanisms by which VB1 benefits plants remaining elusive.
Tengfei Zhang, Jie Zang, Boming Yang, Qiuxia Wang, Jijun Yan, Peiyong Xin, Jinfang Chu, Huabang Chen, Zhaogui Zhang   +8 more
wiley   +1 more source

Comparison of human erythrocyte purine nucleotide metabolism and blood purine and pyrimidine degradation product concentrations before and after acute exercise in trained and sedentary subjects [PDF]

, 2017
Wioleta Dudzińska, M. Suska, Anna Lubkowska, Katarzyna Jakubowska, Maria Olszewska, Krzysztof Safranow, Dariusz Chlubek   +6 more
openalex   +1 more source