Results 201 to 210 of about 42,575 (244)

Modification of Pyrimidine and Purine Nucleotides By "Click" Chemistry: Design, Synthesis and Properties Study

, 2014
Mohammad Mojibul Haque
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Occurrence, Properties, Applications and Analytics of Cytosine and Its Derivatives. [PDF]

Molecules
Kluska M, Jabłońska J, Prukała D, Prukała W.   +3 more
europepmc   +1 more source

Ionization of DNA Nucleotides in Explicit Solution. [PDF]

Molecules
Bai J, Zhang Y, Yin S, Che L, Yang S.
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Expected and Unexpected "Guests" at the Active Site of Human Orotidine 5'-Monophosphate Decarboxylase. [PDF]

Biochemistry
Kirck LL, Santagostino E, Brandhoff L, Simeth NA, Tittmann K.   +4 more
europepmc   +1 more source

Impact of 2'-deoxyribo-purine substrates on nonenzymatic RNA template-directed primer extension. [PDF]

Nucleic Acids Res
Fang Z, Acikgoz O, Jia X, Essex J, Wen R, Szostak JW.   +5 more
europepmc   +1 more source

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Receptors responsive to extracellular pyrimidine nucleotides

Trends in Pharmacological Sciences, 1997
Extracellular adenine nucleotides have long been known to mediate pharmacological responses via several subtypes of P2 purinoceptors. More recently, however, similar responses to uracil nucleotides have been demonstrated. Here, Didier Communi and Jean-Marie Boeynaems discuss the evidence to suggest that distinct pyrimidinoceptors do indeed exist ...
Communi, Didier, Boeynaems, Jean-Marie
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Pyrimidine nucleotide metabolism in cardiac hypertrophy

European Heart Journal, 1984
Cardiac hypertrophy was induced in rats either by isoprenaline treatment or by experimental abdominal aortic stenosis. In both models, the UTP content increased in the hypertrophying heart, while the ATP level remained depressed. The rate of net synthesis of uracil nucleotides, estimated by phosphate incorporation into alpha-phosphate groups, was ...
A, Rossi, J, Aussedat, J, Olivarès, A, Ray, M, Verdys   +4 more
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DNA homoduplexes containing no pyrimidine nucleotide

European Biophysics Journal, 2003
We show using polyacrylamide gel electrophoresis that guanine+adenine repeat strands of DNA associate into homoduplexes at neutral pH and moderate ionic strength. The homoduplexes melt in a cooperative way like the Watson-Crick duplex, although they contain no Watson-Crick base pair.
Jaroslav, Kypr, Iva, Kejnovská, Michaela, Vorlícková   +2 more
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Leflunomide interferes with pyrimidine nucleotide biosynthesis

Inflammation Research, 1995
Leflunomide is an anti-inflammatory and immunosuppressive agent which blocks proliferation of transformed cells and mitogen stimulated normal lymphocytes but does not block T cell signaling mechanisms at antiproliferative concentrations. These properties are consistent with a mechanism involving interference with nucleotide metabolism.
H M, Cherwinski, N, Byars, S J, Ballaron, G M, Nakano, J M, Young, J T, Ransom   +5 more
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Nucleic Acids, Purines, Pyrimidines (Nucleotide Synthesis)

Annual Review of Biochemistry, 1959
period and has been inc luded. The factors involved in nucleotide and nu­ cleic acid synthesis in vivo have also been discussed. With certain excep­ tions, extensive discussion has been omitted of topics related to the partici­ tion of nucleotides in other metabolic processes to be revie wed in this vol­ ume, such as protein synthesis and carbohydrate ...
S C, HARTMAN, J M, BUCHANAN
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