Results 61 to 70 of about 42,575 (244)
Microorganisms‘Candidatus Phytoplasma mali’ is associated with apple proliferation, a devastating disease in fruit production. Using genome analysis, a gene encoding a hemolysin-like protein was identified.
Kajohn Boonrod +3 more
doaj +1 more source
Chemistry – A European Journal, EarlyView.5‐Substituted 2‐(naphthalen‐2‐yl)‐4H‐chromen‐4‐ones are reported as a novel class of highly potent and selective triplex DNA ligands. These ligands induce triplex formation at submicromolar concentrations and inhibit enzymatic activity via ligand‐mediated triplex formation.
Nghia Tran +4 more
wiley +1 more source
Mitochondrial NME6: A Paradigm Change within the NME/NDP Kinase Protein Family?
CellsEukaryotic NMEs/NDP kinases are a family of 10 multifunctional proteins that occur in different cellular compartments and interact with various cellular components (proteins, membranes, and DNA).
Bastien Proust +4 more
doaj +1 more source
Rational Design Strategies for Stimuli‐Responsive DNAzymes Using Modified and Artificial Nucleotides
Chemistry – A European Journal, EarlyView.Activity control of RNA‐cleaving DNAzymes in response to external stimuli has attracted growing interest for applications in DNA‐based diagnostics, therapeutics, and dynamic DNA nanotechnology. This review summarizes rational design strategies for stimuli‐responsive DNAzymes using modified or artificial nucleotides, including split and caged DNAzymes ...
Yusuke Takezawa, Mitsuhiko Shionoya
wiley +1 more source
Research progress of dCTP pyrophosphatase 1 regulating nucleotide metabolism and phenotype of tumor cells [PDF]
Jichu yixue yu linchuang, 2021 Deoxycytidine triphosphate pyrophosphatase 1(dCTP pyrophosphatase 1, DCTPP1) is a newly discovered pyrophosphatase targeting deoxycytidine triphosphate (dCTP).
LI Jing, ZHANG Mei-gui, BAI Zhong-tian
doaj
Carbohydrate Research, 2020 Nucleosides and nucleotides are a group of small molecule effectors and substrates which include sugar nucleotides, purine and pyrimidine-based nucleotide phosphates, and diverse nucleotide antibiotics. We previously reported that hydrogenation of the nucleotide antibiotic tunicamycin leads to products with reduced toxicity on eukaryotic cells.
Neil P J, Price +4 more
openaire +3 more sources
Food Frontiers, EarlyView.In this study, we investigated the protective effects of different membrane‐separated ripe Pu‐erh tea on alcohol‐induced liver injury. The result indicated that ripe Pu‐erh tea separated by a 50 nm ceramic membrane (molecular weight < 300 kDa) has the best effect on preventing ALD.
Sibo Zhao +9 more
wiley +1 more source
High-throughput continuous evolution of compact Cas9 variants targeting single-nucleotide-pyrimidine PAMs [PDF]
, 2022 Tony P. Huang +7 more
openalex +1 more source
Food Frontiers, EarlyView.Auricularia auricula polysaccharides (AAP; 100, 200, and 400 mg/kg) protect against acute lung injury (ALI) by dose‐dependently remodeling the gut microbiota and modulating associated metabolic pathways via the gut‐lung axis, thereby enhancing pulmonary anti‐inflammatory and antioxidant capacity to ultimately prevent tissue damage.
Haili Niu +8 more
wiley +1 more source
Food Frontiers, EarlyView.This large cohort study of 45,664 participants from the UK Biobank provides strong epidemiological evidence that fish oil use was associated with 12% and 7% lower risks of obesity and high body fat percentage, respectively. Mechanistically, marine n‐3 polyunsaturated fatty acids mitigate obesity traits through PRDM16‐driven gene–nutrient interactions ...
Xiaohui Liu +12 more
wiley +1 more source