Treadmill training or caloric restriction delays aging-associated increase in urocortin 2-induced hyperthermia in middle-aged male Wistar rats. [PDF]
Kovacs DK +5 more
europepmc +1 more source
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang +3 more
wiley +1 more source
Interpretation guidance for MHRA regulatory considerations for phage therapeutic products. [PDF]
Coxon C +13 more
europepmc +1 more source
We describe a very elderly patient with ECOG performance status 2 who initially declined systemic therapy because of concerns about adverse events but later achieved symptom improvement and sustained disease control with reduced‐dose dabrafenib and trametinib.
Shun Suyama +5 more
wiley +1 more source
Antifungal, antibacterial, and anti-inflammatory activity of glycerol dithionomonolaurate, an analog of glycerol monolaurate. [PDF]
Schlievert PM +3 more
europepmc +1 more source
Uterine Rupture Cases Over 15 Years in a District General Hospital: A Retrospective Case Series
ABSTRACT Objective To evaluate the incidence, clinical presentation, management, and maternal and neonatal outcomes of uterine rupture over a 15‐year period in a UK district general hospital, and to assess local practice against the Royal College of Obstetricians and Gynaecologists (RCOG) Green‐top Guideline No. 45.
Asmaa Badr, Alexa Vardy
wiley +1 more source
Endotoxin Detection in Magnetic Resonance Imaging Contrast Agent Using Optimising Chromogenic Limulus Amebocyte Lysate Assay. [PDF]
Ab Aziz A +5 more
europepmc +1 more source
Personalized Cancer Vaccines in the Clinical Trial Pipeline
ABSTRACT Aim To present an overview of personalized cancer vaccines currently undergoing clinical development, aiming to enhance awareness and promote collaboration among academic, commercial researchers, and non‐profit communities. Methods A dataset of 78 clinical trials for personalized cancer vaccines was generated using ClinicalTrials.gov database ...
Liudmila Iamukova, Elena Alferova
wiley +1 more source
Evaluation of the effect of cell freshness on pyrogen detection using a serum-free monocyte-activation test. [PDF]
Hayashi K +8 more
europepmc +1 more source
Paracetamol prescribing to small animals by veterinarians in Australia and New Zealand
Objective To describe the prescribing patterns of paracetamol by veterinarians in Australia and New Zealand. Methods An online survey was created and distributed to veterinarians in Australia and New Zealand over a 3‐month period (July–October 2024).
A Tse, W Chee, CJ Boyd, CR Sharp
wiley +1 more source

