Results 171 to 180 of about 11,970 (271)

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang   +3 more
wiley   +1 more source

Interpretation guidance for MHRA regulatory considerations for phage therapeutic products. [PDF]

open access: yesMicrobiology (Reading)
Coxon C   +13 more
europepmc   +1 more source

Reduced‐Dose Dabrafenib–Trametinib for BRAF V600E–Mutant Lung Adenocarcinoma in a Very Elderly Patient With ECOG PS 2

open access: yesRespirology Case Reports, Volume 14, Issue 6, June 2026.
We describe a very elderly patient with ECOG performance status 2 who initially declined systemic therapy because of concerns about adverse events but later achieved symptom improvement and sustained disease control with reduced‐dose dabrafenib and trametinib.
Shun Suyama   +5 more
wiley   +1 more source

Uterine Rupture Cases Over 15 Years in a District General Hospital: A Retrospective Case Series

open access: yesReproductive, Female and Child Health, Volume 5, Issue 2, June 2026.
ABSTRACT Objective To evaluate the incidence, clinical presentation, management, and maternal and neonatal outcomes of uterine rupture over a 15‐year period in a UK district general hospital, and to assess local practice against the Royal College of Obstetricians and Gynaecologists (RCOG) Green‐top Guideline No. 45.
Asmaa Badr, Alexa Vardy
wiley   +1 more source

Personalized Cancer Vaccines in the Clinical Trial Pipeline

open access: yesAsia-Pacific Journal of Clinical Oncology, Volume 22, Issue 3, Page 362-368, June 2026.
ABSTRACT Aim To present an overview of personalized cancer vaccines currently undergoing clinical development, aiming to enhance awareness and promote collaboration among academic, commercial researchers, and non‐profit communities. Methods A dataset of 78 clinical trials for personalized cancer vaccines was generated using ClinicalTrials.gov database ...
Liudmila Iamukova, Elena Alferova
wiley   +1 more source

Evaluation of the effect of cell freshness on pyrogen detection using a serum-free monocyte-activation test. [PDF]

open access: yesPLoS One
Hayashi K   +8 more
europepmc   +1 more source

Paracetamol prescribing to small animals by veterinarians in Australia and New Zealand

open access: yesAustralian Veterinary Journal, Volume 104, Issue 6, Page 327-333, June 2026.
Objective To describe the prescribing patterns of paracetamol by veterinarians in Australia and New Zealand. Methods An online survey was created and distributed to veterinarians in Australia and New Zealand over a 3‐month period (July–October 2024).
A Tse, W Chee, CJ Boyd, CR Sharp
wiley   +1 more source

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