Results 71 to 80 of about 2,162 (216)

Ad5 Shaft Does Not Contain Human Neutralization Epitopes and Contributes to In Vivo Immunogenicity and Pyrogenicity of rAd5 Vector

open access: yes, 2013
(A) Mice were injected with rAd5 or a chimeric rAd5 containing the knob region from Ad35 at 1010 viral particles (Ad5 35knob). Cellular immune responses were assessed by analysis of intracellular cytokine staining in CD4+ or CD8+ cells, and antibody ...
Wing-pui Kong (68823)   +6 more
core   +1 more source

Temperature‐Dependent Effects of Laboratory‐Heated Dissolved Organic Matter on Aquatic Microbiome Composition and Nitrogen Cycling Dynamics

open access: yesJournal of Geophysical Research: Biogeosciences, Volume 131, Issue 6, June 2026.
Abstract Wildfires generate partially combusted biomass that mobilizes to aquatic ecosystems as dissolved pyrogenic organic matter (dPyOM) in runoff, where it can impact surface water quality. However, the influence of dPyOM on aquatic microbiome composition, functional gene distribution, and biogeochemical processes remains poorly understood, with ...
Saraf Islam Promi   +3 more
wiley   +1 more source

Bioethical Aspects of Improving the Production of Rabies Immunoglobulin in Russia

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2020
The main objective of the present research was to review the studies that look into ways of improving production of anti-rabies immunoglobulin in terms of bioethical principles: ensuring patients’ right to receive quality pharmaceutical care, and ...
S. V. Generalov   +2 more
doaj   +1 more source

Foliar Contributions to Methane and Nitrous Oxide Exchange in Urban Green Roof Systems

open access: yesGCB Bioenergy, Volume 18, Issue 6, June 2026.
Biochar amendment of extensive green roof substrates enhanced foliar methane (CH4) uptake (~3×) and reduced nitrous oxide (N2O) emissions across native and stonecrop vegetation. City‐scale extrapolation to Toronto's permitted green roof area indicates measurable, management‐sensitive non‐CO2 mitigation within urban green infrastructure systems ...
Md Rezaul Karim, Sean C. Thomas
wiley   +1 more source

In vitro and in vivo evaluation of lyophilized bovine bone biocompatibility

open access: yesClinics, 2008
INTRODUCTION: The use of bone grafts in orthopedic, maxillofacial and dental surgery has been growing. Nevertheless, both fresh autografts and frozen allografts have limitations, and therefore, alternative synthetic or natural biomaterials, such as ...
Carlos Roberto Galia   +5 more
doaj   +1 more source

Nrf2/NOX2 Pathway Dysregulation and Oxidative Stress Biomarkers in Gaucher Disease–Associated Parkinsonism: Insights Into a Potential Therapeutic Target

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder, yet its underlying genetic and molecular mechanisms remain incompletely understood. Variants in the GBA gene, encoding the lysosomal enzyme glucocerebrosidase, are not only responsible for Gaucher disease (GD) but also represent a significant genetic risk factor ...
Alessio Ardizzone   +8 more
wiley   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

open access: yesJournal of Gastroenterology and Hepatology, Volume 41, Issue 6, Page 1722-1742, June 2026.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin   +2 more
wiley   +1 more source

The Outcome of Intracellular Selenomonas sputigena and its Impact on Gingival Keratinocytes

open access: yesMolecular Oral Microbiology, Volume 41, Issue 3, Page 131-144, June 2026.
ABSTRACT Selenomonas sputigena is an understudied oral pathobiont associated with periodontitis and dental caries. We recently demonstrated that S. sputigena binds to gingival epithelial cells (GECs), where afterwards the bacterium causes robust in vitro pro‐inflammatory cytokine production and migration of monocytes and neutrophils.
Colin G. Hawkes   +6 more
wiley   +1 more source

DataSheet1_Non-pyrogenicity and biocompatibility of parylene-coated magnetic bead implants.PDF

open access: yes
Clinical grade magnetic bead implants have important applications in interfacing with the human body, providing contactless mechanical attachment or wireless communication through human tissue.
Hugh M. Herr (10160868)   +4 more
core   +1 more source

Lipopolysaccharides from Microcystis Cyanobacteria-Dominated Water Bloom and from Laboratory Cultures Trigger Human Immune Innate Response

open access: yesToxins, 2019
Massive toxic blooms of cyanobacteria represent a major threat to water supplies worldwide. Here, the biological activities of lipopolysaccharide (LPS) isolated from Microcystis aeruginosa, the most prominent cyanobacteria in water bloom, were studied ...
Zdena Moosová   +7 more
doaj   +1 more source

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