Results 51 to 60 of about 3,196 (237)
Epilepsia, EarlyView.This graphical abstract provides an overview of the content from this open‐label extension study of fenfluramine use in patients with Dravet syndrome or Lennox‐Gastaut syndrome. Abstract Objective Long‐term safety and global functioning are reported in patients with Dravet syndrome (DS) or Lennox–Gastaut syndrome (LGS) treated with fenfluramine in an ...
Antonio Gil‐Nagel +18 more
wiley +1 more source
Preparation and testing of solutions for organ perfusion and preservation in transplantation [PDF]
Vojnosanitetski Pregled, 2008 Background/Aim. Histidine-tryptophan-ketoglutarate (HTK) solution is the most frequently used solution for the preservation of abdominal organs by leading transplant centers worldwide.
Antunović Mirjana, Aleksić Dragana
doaj +1 more source
Epilepsia Open, EarlyView.This graphical abstract provides an overview of the content from this post hoc analysis describing the trajectories of fenfluramine effectiveness and safety, along with dose changes over time, in patients with Lennox‐Gastaut syndrome. Abstract In the phase 3 randomized controlled trial (RCT; NCT03355209) of fenfluramine in Lennox–Gastaut syndrome (LGS),
Rima Nabbout +14 more
wiley +1 more source
Frontiers in Pharmacology, 2012 Fifty years after the elucidation of lipopolysaccharides (LPS, endotoxin) as the principal structure of Gram-negative bacteria activating the human immune system, its Gram-positive counterpart is still under debate.
Thomas eHartung +2 more
doaj +1 more source
Epilepsia Open, EarlyView.This graphical abstract provides an overview of the content from this post hoc analysis evaluating the efficacy and safety of fenfluramine in patients with Dravet syndrome stratified by age, number of previously attempted antiseizure medications, and SCN1A pathogenic variant status using data pooled from the three pivotal randomized controlled trials ...
Rima Nabbout +20 more
wiley +1 more source
Pteridines, 1999 The rabbit pyrogen assay identifies pyrogenic contaminations in drugs i.l1tend~d for parenteral use. In order to replace this test because of ethical and economical reasons, various in vitro methods have been developed in recent years. Here, we summarize
Peterbauer Anja +2 more
doaj +1 more source
Development of a prognostic scoring system for systemic inflammatory response syndrome in donkeys
Equine Veterinary Journal, EarlyView.Abstract Background Systemic inflammatory response syndrome (SIRS) is associated with increased mortality in horses with gastrointestinal (GI) disease. However, there are no data relating to naturally occurring SIRS in donkeys. Objectives To determine SIRS frequency in donkeys with GI disease. To develop a donkey‐specific prognostic SIRS score.
Marine A. Barnabé +5 more
wiley +1 more source
Leptospires in field Rats in and around the laboratory animal facilities of Banglore, India [PDF]
Veterinary World, 2011 The present study was undertaken to determine the prevalence of leptospires in field rats in and around laboratory animal facilities in Bangalore. 34 rats were trapped alive in and around the laboratory animal facilities in Bangalore.
G. Vinodkumar +4 more
doaj
Head &Neck, EarlyView.ABSTRACT Background Supportive care needs of patients receiving immune checkpoint inhibitors (ICIs) for head and neck squamous cell carcinoma (HNSCC) are ill‐defined. Hence, known treatment‐related adverse events (TRAEs) and health‐related quality of life (HRQoL) associated with ICI treatment for HNSCC were examined to inform future supportive care ...
N. D. O'Donnell +11 more
wiley +1 more source
The Role of Lipopolysaccharide-Induced Extracellular Vesicles in Cardiac Cell Death
Biology, 2019 Exosomes play a crucial role in the progression of infectious diseases, as exosome release and biogenesis are affected by external factors, such as pathogenic infections.
Courtnee’ R. Bell +7 more
doaj +1 more source