Results 41 to 50 of about 3,436 (197)

Method for Determining Pyrogenicity Using Monocytes: Prospects and Features of Application (Review)

open access: yesРегуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Determination of pyrogenic contaminants in medicines is a critical quality indicator that guarantees the preservation of life and health of patients.
E. O. Chechetova   +2 more
doaj   +1 more source

Development, validation and applications of the monocyte activation test for pyrogens based on human whole blood

open access: yes, 2009
Microorganisms such as Gram-negative or Gram-positive bacteria, viruses and fungi contain components that activate the innate immune system. These components, called pyrogens (Greek: pyros=fire), can occur independently of viable microorganisms and are a
Daneshian, Mardas   +3 more
core   +1 more source

Quality Control Tests and Acceptance Criteria of Diagnostic Radiopharmaceuticals

open access: yesKorean Journal of Clinical Laboratory Science, 2021
Radiopharmaceuticals are drugs that contain radioisotopes and are used in the diagnosis, treatment, or investigation of diseases. Radiopharmaceuticals must be manufactured in compliance with good manufacturing practice regulations and subjected to ...
Jun Young Park
doaj   +1 more source

Effect of the Low-Pressure Microwave Discharges on the Pyrogens Bioactivity

open access: yes, 2006
The effect of microwave discharge on the pyrogens bioactivity has been studied in different oxygen and hydrogen containing mixtures with the aim of identifying the crucial de-pyrogenization agent.
KYLIAN Ondrej   +2 more
core   +1 more source

A New Method to Measure Air-Borne Pyrogens Based on Human whole Blood Cytokine Response

open access: yes, 2005
Air-borne microorganisms, as well as their fragments and components, are increasingly recognized to be associated with pulmonary diseases, e.g. organic dust toxic syndrome, humidifier lung, building-related illness, "Monday sickness." We have previously ...
VON AULOCK Sonja   +7 more
core   +2 more sources

Interferon-γ-primed monocytoid cell lines: optimizing their use for in vitro detection of bacterial pyrogens

open access: yes, 2000
In order to reduce animal testing for quality control of pharmaceutical agents intended for parenteral use, the Limulus amebocyte lysate (LAL) assay is now being accepted in many cases as an alternative to measuring pyrogenic activity of samples in ...
Thomas W Jungi   +9 more
core   +1 more source

Pyrogens fail to produce fever in a cordylid lizard

open access: yes, 1981
We investigated the effects on body temperature of the lizard Cordylus cataphractus of intracardiac injections of leucocyte pyrogen (LP) synthesized from rabbit blood and of killed Aeromonas hydrophila, a gram-negative bacterium reputed to be pathogenic
D. Mitchell   +3 more
core   +1 more source

A Novel Antibacterial Compound from Siegesbeckia glabrescens

open access: yesMolecules, 2012
The crude methanol extract of the dried aerial parts of Siegesbeckia glabrescens (Compositae) showed antibacterial activity against the foodborne pathogen Staphylococcus aureus.
Deokhoon Park   +9 more
doaj   +1 more source

Optimization of the In vitro Pyrogen Test (IPT) Regarding Detection of Pyrogens in Air Samples

open access: yes, 2020
ii Sammanfattning Pyrogener kallas ämnen som framkallar feber och de kan exempelvis bestå av hela eller delar av bakterier, virus eller svamp (fungi). En metod som kallas för in vitro pyrogen test (IPT) har utvecklats för att detektera dessa pyrogener ...
Examiner Per Leanderson   +2 more
core  

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