Results 21 to 30 of about 3,436 (197)

Anticancer and Antimicrobial Activity of Some New 2,3-Dihydro-1,5-benzodiazepine Derivatives

open access: yesHeteroatom Chemistry, 2023
A series of 2,3-dihydro-1,5-benzodiazepine derivatives have been synthesized and characterized using IR, NMR, GC-MS, single crystal XRD, and microanalysis.
Felix Odame   +6 more
doaj   +1 more source

Whole Blood Assay Detects Endotoxin and Non-Endotoxin Pyrogens (P3098)

open access: yes, 2013
Pyrogenic contaminations may precipitate adverse effects that range from fever to death. There is limited surveillance on non-endotoxin pyrogens and a sensitive technique to detect them is essential.
Vysyaraju, Kranthi   +4 more
core   +1 more source

Antibacterial Diterpenes from the Roots of

open access: yesNatural Product Communications, 2008
Investigation of the roots of Ceriops tagal led to the isolation of a new isopimarane, together with the known diterpenes isopimar-8(14)-en-15,16-diol and erythroxyl-4(17),15(16)-dien-3-one.
Musa Chacha   +3 more
doaj   +1 more source

Disruptive technologies for hemodialysis: medium and high cutoff membranes. Is the future now?

open access: yesBrazilian Journal of Nephrology, 2021
In the past decade, a new class of hemodialysis (HD) membranes (high retention onset class) became available for clinical use. The high cutoff (HCO) and the medium cutoff (MCO) membranes have wider pores and more uniformity in pore size, allowing an ...
Thiago Reis   +3 more
doaj   +2 more sources

Kinetic Bacterial Endotoxin Testing Methods: Specifics of Analytical Conditions Exemplified by Medicinal Products from Different Classes

open access: yesРегуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Kinetic bacterial endotoxin (BE) testing methods based on amoebocyte lysate from the haemolymph of the horseshoe crab can quantify BEs in parenteral medicinal products across a broad range of concentrations. To develop a specific analytical
О. V. Shapovalova   +2 more
doaj   +1 more source

Pyrogens, a polypeptide produces fever by metabolic changes in hypothalamus: Mechanisms and detections.

open access: yes, 2019
Fever is one of the cardinal symptoms of onset of an infection or inflammation and is the common clinical indicator for medical consultation in mammalian host worldwide.
Athira, SS, Prajitha, N, Mohanan, PV
core   +1 more source

Persistence of febrile response to pyrogens after PO/AH lesions in squirrel monkeys

open access: yes, 1976
Observation of a patient who developed fever in spite of severe CNS sarcoidosis led us to test the idea that febrile responses require mediation by neurons in the preoptic/anterior hypothalamic (PO/AH) region. Changes in rectal and skin temperatures and
GP Trzcinka, JM Lipton
core   +1 more source

Fever, fever patterns and diseases called ‘fever’ – A review

open access: yesJournal of Infection and Public Health, 2011
Summary: Fever is a prominent feature of disease since antiquity. The febrile response is orchestrated by the central nervous system through endocrine, neurological, immunological and behavioural mechanisms.
Dimie Ogoina
doaj   +1 more source

The efficacy of steroids in reducing morbidity and mortality from extreme hyperthermia and heatstroke—A systematic review

open access: yesPharmacology Research & Perspectives, 2020
Severe hyperthermia from classical or exertional heatstroke, or from drug ingestion or other noninfective pyrogens, is associated with a high mortality and morbidity.
Edward Walter, Oliver R. Gibson
doaj   +1 more source

Cotton fever: A case report and review of the literature

open access: yesJEM Reports, 2023
Background: The term “cotton fever” describes a benign, self-limited febrile response within minutes following cotton filter use with intravenous (IV) drug injection.
Natasha Tobarran   +5 more
doaj   +1 more source

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