Results 11 to 20 of about 3,436 (197)

Pyrogens Enhance β-Endorphin Release in Hypothalamus and Trigger Fever That Can Be Attenuated by Buprenorphine

Journal of Pharmacological Sciences, 2003
: At first, we investigated whether both β-endorphin release level in the hypothalamus and body temperature can be altered after intracerebroventricular (i.c.v.) injection of either lipopolysaccharide (LPS), interleukin-1β (IL-1β), or prostaglandin E2 ...
Shu-Ming Tsai, Mao-Tsun Lin, Jhi-Joung Wang, Wu-Tein Huang   +3 more
doaj   +2 more sources

Systematic review of membrane components of Gram-positive bacteria responsible as pyrogens for inducing human monocyte / macrophage cytokine release

Frontiers in Pharmacology, 2012
Fifty years after the elucidation of lipopolysaccharides (LPS, endotoxin) as the principal structure of Gram-negative bacteria activating the human immune system, its Gram-positive counterpart is still under debate.
Thomas eHartung, Thomas eHartung, Christoph eRockel   +2 more
doaj   +2 more sources

Development of a Monocyte Activation Test as an Alternative to the Rabbit Pyrogen Test for Mono- and Multi-Component Shigella GMMA-Based Vaccines

Microorganisms, 2021
Generalised modules for membrane antigens (GMMA)-based vaccines comprise the outer membrane from genetically modified Gram-negative bacteria containing membrane proteins, phospholipids and lipopolysaccharides.
Danielle Carson, Sophie Myhill, Elena Palmieri, Francesca Necchi, Sjoerd Rijpkema, Francesca Micoli, Ida Karin Nordgren, Omar Rossi, Caroline Vipond   +8 more
doaj   +1 more source

Recombinant bacterial endotoxin testing: a proven solution

BioTechniques, 2021
Testing of parenteral pharmaceuticals and medical devices for pyrogens (fever-inducing substances) is critical to patient safety. The original rabbit pyrogen test has largely been replaced by different bacterial endotoxin tests based on Limulus amebocyte
Brendan Tindall, Dogan Demircioglu, Thomas Uhlig   +2 more
doaj   +1 more source

Microbial and Host Metabolites at the Backstage of Fever: Current Knowledge about the Co-Ordinate Action of Receptors and Molecules Underlying Pathophysiology and Clinical Implications

Metabolites, 2023
Fever represents an elevation of body temperature, that exerts a protective effect against pathogens. Innate immune cells and neurons are implicated in the regulation of body temperature.
Luigi Santacroce, Marica Colella, Ioannis Alexandros Charitos, Marina Di Domenico, Raffaele Palmirotta, Emilio Jirillo   +5 more
doaj   +1 more source

Endotoxins from a Pharmacopoeial Point of View

Toxins, 2018
A pyrogen is a substance that causes fever after intravenous administration or inhalation. Gram negative endotoxins are the most important pyrogens to pharmaceutical laboratories. In the International, United States, Japanese and European Pharmacopoeias,
Elvira Franco, Verónica Garcia-Recio, Pilar Jiménez, Manuel Garrosa, Tomás Girbés, Manuel Cordoba-Diaz, Damián Cordoba-Diaz   +6 more
doaj   +1 more source

Pyrogens

, 1956
ARTHUR BERGER, GILBERT D. ELENBOGEN, LEONARD G. GINGER   +2 more
openaire   +2 more sources

Avaliação de pirogênios em produtos de uso veterinário pelos testes da hipertermia em coelhos e do lisado de amebócitos do Limulus Pyrogens in veterinary products by the rabbit pyrogen test and the Limulus amoebocyte lysate test

Ciência Rural, 2007
Realizou-se a avaliação de pirogênios em produtos veterinários de uso parenteral, pelo método da hipertermia em coelhos, calculando-se, para o teste das amostras, doses com concentrações de três a sete vezes superiores à terapêutica.
Thiago Barth, Volmir João Dalmora, Felipe Bianchini D'Avila, Sérgio Luiz Dalmora   +3 more
doaj   +1 more source

Assessment of the knowledge and attitude of Jos residents toward the prevention and treatment of fever

Medical Journal of Dr. D.Y. Patil University, 2015
Background: A fever is a temporary increase in the body temperature, indicating that something out of the ordinary is going on in the body. Fever is a common sign of changes in the body of patients and a common cause of hospital visits, especially for ...
Jimam S Nanloh, Galam Z Nanyak, Dangiwa A Dauda   +2 more
doaj   +1 more source

To pediatrician about feverish conditions in children: what to know and know how

Медицинский совет, 2016
Fever is one of the most common nonspecific reactions to various pathological processes in children. The article tells about the specifics of thermoregulation processes, etiology and pathogenesis of fever in children, mechanisms of action of antipyretics.
I. N. Zakharova, A. L. Zaplatnikov, T. M. Tvorogova, E. B. Machneva   +3 more
doaj   +1 more source