Evaluation of Pyrrole Heterocyclic Derivatives as Selective MAO-B Inhibitors and Neuroprotectors. [PDF]
Georgieva M +4 more
europepmc +1 more source
The present study demonstrates the transformation of dual‐emissive H‐bonded molecular clusters of fluorophores into single emissive amorphous carbon nanodots and their structure‐property relationship in fluorescence‐based sensing of Bilirubin and Cu2+ ions. The present study aims to explore the origin of fluorescence in nitrogen‐doped carbon dots (NCDs)
Rajarshi Basu +6 more
wiley +1 more source
Computational investigation of anticorrosion properties in Ethyl 4-[(E)-(2-Hydroxy-4-Methoxyphenyl)Methyleneamino]Benzoate and its pyrrole substituted variant on mild steel. [PDF]
Kiven DE +4 more
europepmc +1 more source
Electrochemical Cascade N‐Acylation and C–H Halogenation of Azaindoles
Substituted azaindoles are valuable yet synthetically challenging scaffolds. Here, we report an electrochemical cascade strategy that combines N‐acylation with electro‐induced C–H halogenation in a single, atom‐economical process. This additive‐free method enables efficient synthesis of halogenated N‐acyl azaindole amides and carbamates from readily ...
Sudipta Ponra +4 more
wiley +1 more source
Copper- and Silver-Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five- and Six-Membered Heterocycles. [PDF]
George J, Oh K.
europepmc +1 more source
Through ZnO‐templated localized assembly, a branched network was constructed with in‐situ grown carbon nanotubes and abundant mesopores formed upon template removal, yielding a hierarchical structure combining high surface area with efficient mass transport.
Yafeng Li +8 more
wiley +1 more source
An Alkaloid Biosynthetic Gene Bundle in Animals. [PDF]
Kim JG, Lin Z, Agarwal V, Schmidt EW.
europepmc +1 more source
Contemporary Applications of Chemical Libraries for Drug Discovery and Methods for Their Synthesis
Screening of chemical libraries has over the past decades become a cornerstone of drug discovery. Today, a broad range of chemical libraries exist but they are often not well described in terms of diversity. This review describes current efforts which aim to visualize chemical diversity in compound collections and discuss current trends in synthetic ...
Tobias N. Hansen, Nils J. V. Hansen
wiley +1 more source
Quantifying Carboxylate Burial in Synthetic Hydrophobic Pockets in Water
How “buried” is a buried ion? Double mutant cycles quantify the cost of placing a carboxylate within a deep aromatic calix[4]pyrrole pocket in water. The penalty is only +1.3 to +3.0 kcal·mol−1 because water penetrates through cracks and the portal, creating a wet, high‐dielectric microenvironment.
Esteban A. Valencia +4 more
wiley +1 more source
Study on quality evaluation of the entire stir-frying process of charred stir-fried malt based on intelligent sensing and machine learning. [PDF]
Wang X +9 more
europepmc +1 more source

