A Half-Century of Supramolecular Thermodynamics: A Retrospective of Our Multidisciplinary Approach. [PDF]
Danil de Namor AF, Al Hakawati N.
europepmc +1 more source
Selective N‐Functionalization of Pyrazoles
This review traces the evolution of regioselective N‐functionalization strategies for pyrazoles, a key class of nitrogen heterocycles widely used in medicinal chemistry. Due to rapid tautomerism, N‐functionalization often lacks selectivity, leading to poor and unpredictable regioisomeric outcomes.
Lucas Popek +2 more
wiley +1 more source
A sulfonic acid-functionalized amine-linked covalent organic framework as a robust catalyst for the preparation of pyrrole-2-ones. [PDF]
Oghan M +4 more
europepmc +1 more source
Navigating the Radical Oxo‐Functionalization of Alkenes Toward Ketones
Straightforward access to complex ketones in a single synthetic step: This Review surveys the latest advances in three‐component alkene 1,2‐oxo‐functionalizations. The opportunities unlocked by the so‐called single‐electron (1e–) logic, including access to a broad pool of radical precursors and carbonyl oxygen atom sources, are highlighted.
Mattia Lepori +3 more
wiley +1 more source
Click Bioconjugation of Aza‐BODIPY Fluorophores to LfcinB Peptides for Improved Biocompatibility
Click bioconjugation attaches NIR aza‐BODIPY fluorophores to LfcinB‐derived anticancer peptides via CuAAC and thiol‐maleimide chemistry. Conjugates exhibit improved predicted solubility while retaining strong NIR absorption (703–730 nm). Peptide‐aza‐BODIPY conjugates induce apoptotic morphology in HeLa cancer cells.
A. Verónica Rodríguez‐Mayor +6 more
wiley +1 more source
Direct Access to the Simplest <i>N</i>‑Substituted Pyrroles from Furans Enabled by Tailored Photocatalysts. [PDF]
Byeon H +6 more
europepmc +1 more source
Photocatalysis‐Triggered Click Reactions and Applications
Photoclick chemistry offers broad applications ranging from materials science to bioconjugation, with precise spatiotemporal control over click reactions. Initially limited to UV activation, recent advances have extended photoclick processes to the visible and NIR regions thanks to the photocatalysis.
Margaux Walter +2 more
wiley +1 more source
Photochromism of Dicyanorhodanine-Pyrrole Conjugates: Substituent and Solvent Effects. [PDF]
Das P +4 more
europepmc +1 more source
Pyrrole: a resourceful small molecule in key medicinal hetero-aromatics
Varun Bhardwaj +4 more
semanticscholar +1 more source
Bromonitroalkanes in Organic Synthesis
α,α‐Bromonitroalkanes (BNAs) exhibit chameleon‐like reactivity, serving as carbene, radical, carbanion, and carbocation synthons. This mini‐review summarizes the different reaction modes and highlights recent developments in thermal and photochemical processes. α,α‐Bromonitroalkanes (BNAs) exhibit chameleon‐like reactivity, serving as carbene, radical,
Magdalena Koch, Oliver Reiser
wiley +1 more source

