Results 191 to 200 of about 57,050 (287)

Truncation of Samroiyotmycin: Tailored seco‐Acids as Novel Antimalaria Compounds

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Six truncated samroiyotmycin‐derived antimalarials were synthesized by replacing the tosyloxazole unit with electron‐deficient aryl groups. The most active seco‐acid with EWG = 2 × CF3 outperformed the natural product SamA. Its enhanced activity supports a donor–acceptor interaction involving the electron‐poor aryl unit, consistent with inhibition of ...
Anton Czuczkowski   +10 more
wiley   +1 more source

Regioselective Oxidative Oligomerization of 2‐Tert‐Butylpyrene Toward Structurally Defined Oligomers and Their Application in Organic Light‐Emitting Diodes

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Treatment of 2‐tert‐butylpyrene with Cu2+ afforded structurally well‐defined pyrene oligomers, up to the 13‐mer. Single‐crystal X‐ray diffraction, spectroscopic analyses, and computational studies were conducted to evaluate the properties of the resulting oligopyrenes.
Md Jadu Mia   +14 more
wiley   +1 more source

The Expanding Role of Diazirines in Synthetic Methodology

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Beyond their established role in photoaffinity labeling, diazirines have emerged as versatile reagents in synthetic chemistry. This review highlights their dual reactivity as carbene and nitrogen‐transfer precursors, showcasing mechanistic insights and diverse applications in cyclopropanations, cycloadditions, skeletal editing, amination, heterocycle ...
Viktor Savic   +3 more
wiley   +1 more source

Unusual backfolded binding poses of BAZ2A bromodomain binders. [PDF]

open access: yesActa Crystallogr D Struct Biol
Dalle Vedove A   +5 more
europepmc   +1 more source

Counterion Effects in Decatungstate Photocatalysis

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Decatungstate photocatalysis is often discussed from an anion‐centered perspective, treating the counterion as a passive charge‐balancing species. This review highlights that counterion identity can instead profoundly influence catalyst solubility, ion pairing, aggregation, stability, substrate accessibility, and catalytic performance.
Florence Babawale   +2 more
wiley   +1 more source

Strategic construction of fluorinated surroundings in NIR‐II‐emissive organic semiconducting agents for amplifying cancer phototheranostics

open access: yesFlexMat, EarlyView.
The development of conventional phototheranostic nanomedicines suffers from an intrinsic trade‐off between NIR‐II fluorescence emission and phototherapeutic effects, leading to poor overall efficacy. Herein, we propose an innovative fluorination strategy by constructing fluorinated surroundings in NIR‐II‐emissive organic semiconducting agents to ...
Xiaoming Hu   +7 more
wiley   +1 more source

Strengthened inter‐chain π–π contacts in amorphous diketopyrrolopyrrole polymers for robust flexible organic thin‐film transistors

open access: yesFlexMat, EarlyView.
Vinylene‐linked DPP polymers with expanded thiophene donors achieve strengthened interchain π‐π stacking in near‐amorphous films, enabling high charge mobility and outstanding mechanical stability for flexible organic thin‐film transistors. Abstract Flexible organic thin‐film transistors (OTFTs) based on multi‐vinylene‐linked diketopyrrolopyrrole (DPP)
Yanlin Chen   +11 more
wiley   +1 more source

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