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Synthesis of pyrrole urea and pyrrole carbonylurea derivatives
Tetrahedron, 2009Abstract A series of urea and carbonylurea distamycin analogs whereby the linker has two NH groups for hydrogen bonding with base pairs of DNA were synthesized. The urea and carbonylurea derivatives are prepared from the in situ generation of pyrrole isocyanate (prepared from compound 3 ) and acyl isocyanate (compound 9 ), followed by the reaction ...
Meng-Chi Liu, Chi Wi Ong
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Synthesis of pyrrole and substituted pyrroles (Review)
2017Pyrrole is widely known as a biologically active scaffold which possesses a diverse nature of activities. The combination of different pharmacophores in a pyrrole ring system has led to the formation of more active compounds. Pyrrole containing analogs are considered as a potential source of biologically active compounds that contains a significant set
Tzankova D. +3 more
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Canadian Journal of Chemistry, 1984
Changes in some of the key intermediates and procedures used in our earlier total synthesis of porphobilinogen from pyrrole that improve the yield to 11% are reported. Ethyl pyrrole-3-acetate was formylated by the Vilsmeier–Haack method and then iodinated.
Kurt Faber +3 more
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Changes in some of the key intermediates and procedures used in our earlier total synthesis of porphobilinogen from pyrrole that improve the yield to 11% are reported. Ethyl pyrrole-3-acetate was formylated by the Vilsmeier–Haack method and then iodinated.
Kurt Faber +3 more
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An efficient synthesis of highly substituted pyrrole and bis pyrrole derivatives
Journal of Heterocyclic Chemistry, 2007Abstractmagnified imageAn efficient synthesis of highly substituted pyrrole and bis pyrrole derivatives is reported.
Rajeshwar Reddy Sagyam +3 more
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Bioactive pyrrole-based compounds with target selectivity
European Journal of Medicinal Chemistry, 2020Giovanna Li Petri +2 more
exaly
Pyrroles from azaindoles. Synthesis of porphobilinogen and related pyrroles
Journal of the American Chemical Society, 1969B, Frydman +3 more
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Pyrroles and Fused Pyrroles: Synthesis and Therapeutic Activities
Mini-Reviews in Organic Chemistry, 2013Mosaad Mohamed, Samar Fathallah
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