Results 251 to 260 of about 51,454 (296)

The Synthesis of 3-Substituted Pyrroles from Pyrrole

Synthesis, 1985
La reaction d'electrophiles avec le pyrrole se fait preferentiellement en position 1 ou 2; pour obtenir des derives substitues en 3, on protege d'abord la position 1 ou 2 par des substituants orientant la reaction en position 3 ou on utilise en position 2 des substituants permettant un rearrangement conduisant aux pyrroles substituees en 3; une etape ...
Hugh J. Anderson, Charles E. Loader
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Pyrrole chemistry. XXVII. 2,3,4-Trisubstituted pyrroles and a second synthesis of porphobilinogen from pyrrole

Canadian Journal of Chemistry, 1984
Changes in some of the key intermediates and procedures used in our earlier total synthesis of porphobilinogen from pyrrole that improve the yield to 11% are reported. Ethyl pyrrole-3-acetate was formylated by the Vilsmeier–Haack method and then iodinated.
Kurt Faber, Hugh J. Anderson, Charles E. Loader, Annette S. Daley   +3 more
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Formation and Properties of Cyclo[6]pyrrole and Cyclo[7]pyrrole

Journal of the American Chemical Society, 2003
Oxidative coupling of a tetraalkylbipyrrole under FeIII-mediated coupling conditions in the presence of HCl results in a mixture of cyclo[6]- and cyclo[7]pyrroles, as well as the known cyclo[8]pyrrole. This "matched set" of heteroannulenes was analyzed by spectroscopic, electrochemical, and X-ray diffraction methods.
Thomas, Köhler, Daniel, Seidel, Vincent, Lynch, Forrest O, Arp, Zhongping, Ou, Karl M, Kadish, Jonathan L, Sessler   +6 more
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An efficient synthesis of highly substituted pyrrole and bis pyrrole derivatives

Journal of Heterocyclic Chemistry, 2007
Abstractmagnified imageAn efficient synthesis of highly substituted pyrrole and bis pyrrole derivatives is reported.
Rajeshwar Reddy Sagyam, Himabindu Vurimidi, Pratap Reddy Padi, Mahesh Reddy Ghanta   +3 more
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Synthesis and Evaluation of Cytotoxic Activity of Some Pyrroles and Fused Pyrroles

Anti-Cancer Agents in Medicinal Chemistry, 2017
Pyrrole derivatives represent a very interesting class as biologically active compounds. The objective of our study was to investigate the cytotoxic and apoptotic effects and antioxidant activity of the newly synthesized pyrrole derivatives.A series of novel pyrroles and fused pyrroles (tetrahydroindoles, pyrrolopyrimidines, pyrrolopyridines and ...
Samar S, Fatahala, Mosaad S, Mohamed, Mahmoud, Youns, Rania H, Abd-El Hameed   +3 more
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Pyrrole chemistry. XXIV. The Vilsmeier formylation and the cyanation of pyrrole acetals. A synthesis of pyrrole-2,3,5-tricarboxaldehyde

Canadian Journal of Chemistry, 1982
The preparation of the acetals of a number of pyrrole mono- and dicarboxaldehydes is described. It is shown that, provided the reactivity of the unsubstituted ring positions on the pyrrole nucleus is not too low, a carboxyaldehyde or a carbonitrile group may be substituted onto the pyrrole ring using the Vilsmeier reaction or chlorosulfonyl isocyanate
Charles E. Loader, Graham H. Barnett, Hugh J. Anderson   +2 more
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Simple Synthesis of Substituted Pyrroles.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Bimal K, Banik, Susanta, Samajdar, Indrani, Banik   +2 more
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Synthesis of pyrrole and substituted pyrroles (Review)

2017
Pyrrole is widely known as a biologically active scaffold which possesses a diverse nature of activities. The combination of different pharmacophores in a pyrrole ring system has led to the formation of more active compounds. Pyrrole containing analogs are considered as a potential source of biologically active compounds that contains a significant set
Tzankova D., Vladimirova S., Peikova L., Georgieva M.   +3 more
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Pyrrole acetylenecarbaldehydes: an entry to a novel class of functionalized pyrroles

Tetrahedron Letters, 2016
Abstract The first representatives of a previously unknown class of highly reactive functionalized pyrrole compounds, 3-(pyrrol-2-yl)propiolaldehydes, have been synthesized by the transition metal-free, mechanoactivated ethynylation of pyrroles with 3-iodopropiolaldehyde using a solid K 2 CO 3 medium under mild conditions (room temperature, 4 h) in ...
Maxim D. Gotsko, Lyubov N. Sobenina, Denis N. Tomilin, Marina V. Markova, Igor A. Ushakov, Tamara I. Vakul’skaya, Spartak S. Khutsishvili, Boris A. Trofimov   +7 more
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Pyrrole Pigments

Annual Review of Biochemistry, 1950
R, LEMBERG, J W, LEGGE
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