Results 81 to 90 of about 105,049 (336)

Molecular Docking and ADMET Prediction of Small Molecules Targeting Proteins Involved in Alzheimer’s Disease

open access: yesAppliedChem
Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder characterized by the accumulation of the toxic protein amyloid-β, formation of tau-containing neurofibrillary tangles, neuroinflammation, and synaptic dysfunction, highlighting the ...
Emilio Mateev   +4 more
doaj   +1 more source

Strongly Anisotropic and Rapid Excitons Transport in Organic Crystal

open access: yesAdvanced Science, EarlyView.
The increased exciton diffusion length is beneficial to simplify device design and enhance photoelectric conversion efficiency. But the isotropic exciton diffusion may lead to reduced transport efficiency directed to the charge separation site. Here we have successfully achieved strongly anisotropic and rapid excitons transport in thienopyrrole ...
Minjie Li   +6 more
wiley   +1 more source

PREPARATION AND CHARACTERIZATION OF CONDUCTIVE PAPER VIA IN-SITU POLYMERIZATION OF PYRROLE

open access: yesBioResources, 2010
Electrically conductive paper was prepared via in-situ chemical oxidative polymerization of pyrrole by using ferric chloride as an oxidant and p-toluenesulfonic acid (PTSA) as a dopant.
Chunyue Ding   +3 more
doaj  

Synthesis of Multi-Substituted Pyrrole Derivatives Through [3+2] Cycloaddition with Tosylmethyl Isocyanides (TosMICs) and Electron-Deficient Compounds

open access: yesMolecules, 2018
Pyrrole and its polysubstituted derivatives are important five-membered heterocyclic compounds, which exist alone or as a core framework in many pharmaceutical and natural product structures, some of which have good biological activities. The Van Leusen [
Zhengning Ma, Zi-Cheng Ma, Da-Wei Zhang
semanticscholar   +1 more source

Reactions of Furo[2,3-b]pyrrole and Furo[3,2-b]pyrrole-Type Aldehydes

open access: yes, 1999
The synthesis of methyl 2-formyl-6-(methoxymethyl)furo[2,3-b]pyrrole-5-carboxylate (1d) is described. The reactions of methyl 2-formylfuro[2,3-b]pyrrole-5-carboxylates 1a-1d with malononitrile afforded methyl 2-(2,2-dicyanovinyl)furo[2,3-b]pyrrole-5 ...
Róbert Sleziak   +2 more
core   +1 more source

A Versatile DNA‐Encoded Library Platform for the Discovery of Highly Cooperative Chemical Inducers of Proximity

open access: yesAdvanced Science, EarlyView.
We present a versatile DNA‐encoded library (DEL) platform designed for rapid library synthesis and subsequent screening for chemical inducers of proximity (CIPs) across various presenter proteins of choice. Applying this approach, we discovered a novel molecular glue‐like compound mediating CRBN‐BRD9 ternary complex formation with remarkable ...
Bingqi Tong   +11 more
wiley   +1 more source

“Back-to-Front” Indole Synthesis Using Silver(I) Catalysis: Unexpected C-3 Pyrrole Activation Mode Supported by DFT

open access: yesACS Catalysis, 2018
An efficient silver(I)-catalyzed method is reported for the synthesis of substituted indoles, most notably 5-hydroxy-derivatives, via π-acidic alkyne activation.
A. Clarke   +3 more
semanticscholar   +1 more source

Pyrrole-Based Anion-Responsive π‑Electronic Molecules as Hydrogen-Bonding Catalysts

open access: yes, 2018
The abilities of dipyrrolyldiketone boron complexes as hydrogen-bonding donor organocatalysts were examined by the Mannich-type reaction of N-acyl heteroarenium chlorides with 1-methoxy-2-methyl-1-trimethylsiloxy-1-propene, as well as by the classical N ...
Goki Hirata (1677043)   +1 more
core   +1 more source

Functional MXene Inks for Printed Electronics: Chemistry, Rheology, and Devices

open access: yesAdvanced Science, EarlyView.
Functional MXene inks are emerging as building blocks for MXetronics, connecting MXene synthesis, surface functionalization, ink formulation, and advanced printing with device‐level applications. This review maps how composition, stability, rheology, and processability govern printed structures and enable high‐performance sensors, energy‐storage ...
Shahzaib Ali   +6 more
wiley   +1 more source

Aromatic Pummerer‐Promoted Stereospecific Cross‐Coupling of Thiazoles With Boronic Esters

open access: yesAngewandte Chemie, EarlyView.
A lithiation–borylation–aromatic Pummerer (LiBAP) strategy enables stereospecific, C5‐selective C(sp2)–C(sp3) cross‐coupling of thiazoles with boronic esters. By using exocyclic sulfoxide activation to overcome the low nucleophilicity that frustrates SEAr‐type coupling, the method delivers enantioenriched alkylated thiazoles bearing a versatile C2 ...
Mark John P. Mandigma   +4 more
wiley   +2 more sources

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