Results 161 to 170 of about 27,529 (245)

Inhibiting glioblastoma stem cells by targeting pyruvate carboxylase: A novel therapeutic strategy with both opportunities and challenges. [PDF]

Neuro Oncol
Renoult O, Laurent-Blond M, Pecqueur C.
europepmc   +2 more sources

In silico Analysis of Two Novel Variants in the Pyruvate Carboxylase (PC) Gene Associated with the Severe Form of PC Deficiency. [PDF]

Iran Biomed J, 2023
Maryami F, Rismani E, Davoudi-Dehaghani E, Khalesi N, Talebi S, Mahdian R, Zeinali S.   +6 more
europepmc   +1 more source

Overexpression of cytosolic NADP‐malic enzyme 1 from the common ice plant enhances water‐deficit and high‐light stress tolerance by modulating water‐use efficiency and flavonoid biosynthesis

The Plant Journal, Volume 126, Issue 5, June 2026.
SUMMARY Innovative strategies are essential to enhance crop resilience against drought and heat stress intensified by climate change. Crassulacean acid metabolism (CAM) is a specialized photosynthetic pathway that improves water‐use efficiency (WUE) by shifting CO2 fixation to the nighttime. The common ice plant (Mesembryanthemum crystallinum) utilizes
Sang Hun Kim, Dong Yeol Song, Chan Hui Lee, Seo Young Yang, John C. Cushman, Sung Don Lim   +5 more
wiley   +1 more source

Conformational Selection Governs Carrier Domain Positioning in Staphylococcus aureus Pyruvate Carboxylase. [PDF]

Biochemistry, 2022
Hakala JH, Laseke AJ, Koza AL, St Maurice M.   +3 more
europepmc   +1 more source

The Dual Anaplerotic Model (DAM): Integral Roles of Pyruvate Carboxylase and the GABA Shunt in Beta Cell Insulin Secretion. [PDF]

Life (Basel)
Grubelnik V, Zmazek J, Marhl M.
europepmc   +1 more source

Riboflavin-PLGA nanoparticles enhance the effectiveness of the pyruvate carboxylase inhibitor ZY-444 in targeting lipogenesis in colon and breast cancer. [PDF]

Sci Rep
Siritutsoontorn S, Manohong P, Sawektreeratana N, Kuhakarn C, Katewongsa KP, Jitrapakdee S.   +5 more
europepmc   +1 more source

A Unique Case of Pyruvate Carboxylase Deficiency. [PDF]

Cureus, 2021
Hidalgo J, Campoverde L, Ortiz JF, Ruxmohan S, Eissa-Garcés A.   +4 more
europepmc   +1 more source

Fibroblast pyruvate carboxylase is required for collagen production in the tumour microenvironment. [PDF]

Nat Metab, 2021
Schwörer S, Pavlova NN, Cimino FV, King B, Cai X, Sizemore GM, Thompson CB.   +6 more
europepmc   +1 more source

Pyruvate carboxylase promotes malignant transformation of papillary thyroid carcinoma and reduces iodine uptake. [PDF]

Cell Death Discov, 2022
Liu Y, Liu C, Pan Y, Zhou J, Ju H, Zhang Y.   +5 more
europepmc   +1 more source

Pyruvate Carboxylase

Journal of Biological Chemistry, 1974
openaire   +1 more source