Results 151 to 160 of about 138,584 (219)

Synthesis and Evaluation of 1,3-Disubstituted Imidazolidine-2,4,5-triones as Inhibitors of Pyruvate Carboxylase. [PDF]

ACS Med Chem Lett
Schneider NO, Gilreath K, Henriksen NM, Donaldson WA, Chaudhury S, St Maurice M.   +5 more
europepmc   +1 more source

The mitochondrial enzyme pyruvate carboxylase restricts pancreatic β-cell senescence by blocking p53 activation. [PDF]

Proc Natl Acad Sci U S A
Yang Y, Wang B, Dong H, Lin H, Yuen-Man Ho M, Hu K, Zhang N, Ma J, Xie R, Cheng KK, Li X.   +10 more
europepmc   +1 more source

Glucagon promotes increased hepatic mitochondrial oxidation and pyruvate carboxylase flux in humans with fatty liver disease. [PDF]

Cell Metab
Petersen KF, Dufour S, Mehal WZ, Shulman GI.   +3 more
europepmc   +1 more source

Metabolic profiling of glioblastoma stem cells reveals pyruvate carboxylase as a critical survival factor and potential therapeutic target. [PDF]

Neuro Oncol
Renoult O, Laurent-Blond M, Awada H, Oliver L, Joalland N, Croyal M, Paris F, Gratas C, Pecqueur C.   +8 more
europepmc   +1 more source

Pyruvate Carboxylase Attenuates Myocardial Ischemia-Reperfusion Injury in Heart Transplantation via Wnt/β-Catenin-Mediated Glutamine Metabolism. [PDF]

Biomedicines
Wang Z, Lan H, Wang Y, Zheng Q, Li C, Wang K, Xiong T, Wu Q, Dong N.   +8 more
europepmc   +1 more source

Circ-CAMTA1 regulated by Ca²⁺ influx inhibited pyruvate carboxylase activity and modulate T cell function in patients with systemic lupus erythematosus. [PDF]

Arthritis Res Ther
Yu HC, Tseng HH, Huang HB, Lu MC.
europepmc   +1 more source

Pyruvate carboxylase deficiency type C; variable presentation and beneficial effect of triheptanoin. [PDF]

JIMD Rep
Bernhardt I, Van Dorp L, Dixon M, McSweeney M, Gan C, Baruteau J, Chakrapani A.   +6 more
europepmc   +1 more source

Melanoma-derived versican reactivates tumor-associated macrophages by upregulating pyruvate carboxylase through TLR2-MyD88-RelB axis under normoxia. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Shu Y, Zhou L, Qian J, Zhu WG.
europepmc   +1 more source

In Vivo hyperpolarized carbon‐13 magnetic resonance spectroscopy reveals increased pyruvate carboxylase flux in an insulin‐resistant mouse model

Hepatology, 2013
P. Lee, W. Leong, T. Hing Tan, Miangkee Lim, W. Han, G. Radda   +5 more
semanticscholar   +1 more source

Correction to "Long Noncoding RNA OVAAL Enhances Nucleotide Synthesis Through Pyruvate Carboxylase to Promote 5-Fluorouracil Resistance in Gastric Cancer". [PDF]

Cancer Sci
europepmc   +1 more source