Results 151 to 160 of about 27,529 (245)

Multifunctional Role of Mitochondrial Fatty Acid Oxidation in Cancer Immunotherapy and Aging

Cancer Science, Volume 117, Issue 6, Page 1554-1565, June 2026.
Recent studies have highlighted the complex interplay between tumor immunity, aging, and inflammation. Mitochondrial FAO is a major hub of this physiological interplay. ABSTRACT Recent studies have demonstrated the intricate relationship between tumor immunity, aging, and inflammation.
Koji Kitaoka, Shuhei Hirose, Yu Wang, Tomonori Yaguchi, Kenji Chamoto   +4 more
wiley   +1 more source

Retracted: LINC00092 Modulates Oxidative Stress and Glycolysis of Breast Cancer Cells via Pyruvate Carboxylase-Mediated AKT/mTOR Pathway. [PDF]

Oxid Med Cell Longev, 2023
Longevity OMAC.
europepmc   +1 more source

Energetic stress in combination with impaired fatty acid oxidation induces sequestration of CoA and adaptation of CoA metabolism

The FEBS Journal, Volume 293, Issue 12, Page 3565-3587, June 2026.
Computational modelling and in vitro liver cell experiments indicate that medium‐chain acyl‐CoA dehydrogenase (MCAD) deficiency causes an accumulation of (especially medium‐chain) acyl‐CoAs at the cost of free CoA (CoASH). A substantial decrease in CoASH impairs flux through many pathways essential for energy homeostasis.
Ligia Akemi Kiyuna, Christoff Odendaal, Madhulika Singh, Albert Gerding, Miriam Langelaar‐Makkinje, Marianne van der Zwaag, Asmara Drachman, Vladimíra Cetkovská, Gaby Liem Foeng Kioen, Anne‐Claire M. F. Martines, Nicolette C. A. Huijkman, Hein Schepers, Bart van de Sluis, Dirk‐Jan Reijngoud, Ody C. M. Sibon, Amy C. Harms, Thomas Hankemeier, Barbara M. Bakker   +17 more
wiley   +1 more source

PYRUVIC CARBOXYLASE OF ACETOBACTER SUBOXYDANS

Journal of Biological Chemistry, 1954
T E, KING, V H, CHELDELIN
openaire   +2 more sources

Energy Stress‐Induced Neuroprotection Against Ferroptosis in Dopaminergic Neurons

Journal of Neurochemistry, Volume 170, Issue 6, June 2026.
Energy stress via glucose deprivation activates AMPK and protects dopaminergic neurons from ferroptosis by limiting lipid peroxidation. In contrast, glucose availability supports ferroptosis through oxidizable lipid pools. ABSTRACT Ferroptosis, an iron‐dependent form of regulated necrosis, is implicated in the pathogenesis of Parkinson's disease (PD ...
Aurélie Jonneaux, William Laine, Patrice Maboudou, Jérôme Kluza, Marie‐Amandine Bonte, Flore Gouel, David Devos, Philippe Marchetti, Jean‐Christophe Devedjian   +8 more
wiley   +1 more source

Requirement of hepatic pyruvate carboxylase during fasting, high fat, and ketogenic diet. [PDF]

J Biol Chem, 2022
Selen ES, Rodriguez S, Cavagnini KS, Kim HB, Na CH, Wolfgang MJ.   +5 more
europepmc   +1 more source

The Pyruvate Carboxylase of Aspergillus niger

Journal of Biological Chemistry, 1962
S J, BLOOM, M J, JOHNSON
openaire   +2 more sources

Pyruvate carboxylase from Rhizobium etli: mutant characterization, nucleotide sequence, and physiological

, 1996
Pyruvate carboxylase from Rhizobium etli: mutant characterization, nucleotide sequence, and physiological ...
Michael Frederick Dunn, Yolanda Mora, M. Carmen Vargas, Humberto Peralta, Sergio Encarnacion, Michael F. Dunn, Jaime Mora, Autónoma México   +7 more
core  

Exposure to Gestational Intermittent Hypoxia Does Not Impair the Metabolic Function or Accelerate the Biological Ageing Process of Offspring of Either Sex

Journal of Sleep Research, Volume 35, Issue 3, June 2026.
ABSTRACT Obstructive sleep apnea (OSA), marked by intermittent hypoxia, is associated with obesity, type 2 diabetes and metabolic associated fatty liver disease. In pregnancy, it remains underdiagnosed despite links to gestational diabetes, hypertension, and foetal growth restriction.
Esther Valverde‐Perez, Margarida B. Almeida, Joana F. Sacramento, Elena Olea, Jesus Prieto‐Lloret, Asuncion Rocher, Silvia V. Conde   +6 more
wiley   +1 more source

A PROMOTER::LUCIFERASE reporter system reveals key elements of the circadian regulation of Crassulacean acid metabolism (CAM) in Kalanchoë laxiflora Baker

The Plant Journal, Volume 126, Issue 5, June 2026.
Significance Statement Circadian rhythms of firefly luciferase in the Crassulacean acid metabolism (CAM) species Kalanchoë laxiflora were driven by both CAM and non‐CAM gene promoters, revealing valuable new insights into both the leaf developmental and circadian clock control associated with CAM. The CAM KlGPT2 promoter drove rhythms in K.
Jessica H. Pritchard, Jade L. Waller, Peter J. D. Gould, Nirja Kadu, Susanna F. Boxall, Louisa V. Dever, Jana Kneřová, Diarmuid O'Maoileidigh, James Hartwell   +8 more
wiley   +1 more source