Results 131 to 140 of about 27,301 (195)

Effects of an Hourly Bolus Postruminal Infusion of Flaxseed Oil or Palm Oil on Circulating Fatty Acid Concentrations and Hepatic Expression of Pyruvate Carboxylase and Phosphoenolpyruvate Carboxykinase in Dairy Cattle. [PDF]

Animals (Basel), 2023
Beckett LM, Malacco VMR, Hilger S, Casey TM, Donkin SS.   +4 more
europepmc   +1 more source

Disrupted metabolic flux balance between pyruvate dehydrogenase and pyruvate carboxylase in human fatty liver. [PDF]

Metabolism
Park JM, Lin SH, Baxter JD, Harrison CE, Leary J, Mozingo C, Liticker J, Malloy CR, Jin ES.   +8 more
europepmc   +1 more source

Expanding the genetic spectrum of the pyruvate carboxylase deficiency with novel missense, deep intronic and structural variants. [PDF]

Mol Genet Metab Rep, 2022
Tsygankova P, Bychkov I, Minzhenkova M, Pechatnikova N, Bessonova L, Buyanova G, Naumchik I, Beskorovainiy N, Tabakov V, Itkis Y, Shilova N, Zakharova E.   +11 more
europepmc   +1 more source

Long noncoding RNA OVAAL enhances nucleotide synthesis through pyruvate carboxylase to promote 5-fluorouracil resistance in gastric cancer. [PDF]

Cancer Sci, 2022
Tan JN, Zhou SN, Zhang W, Yang B, Zhong GY, Huang J, Hu H, Han FH, Luo ML.   +8 more
europepmc   +1 more source

Deletion of Pyruvate Carboxylase in Tubular Epithelial Cell Promotes Renal Fibrosis by Regulating SQOR/cGAS/STING-Mediated Glycolysis. [PDF]

Adv Sci (Weinh)
Huang H, Han Y, Zhang Y, Zeng J, He X, Cheng J, Wang S, Xiong Y, Yin H, Yuan Q, Huang L, Xie Y, Meng J, Tao L, Peng Z.   +14 more
europepmc   +1 more source

Synthesis and Evaluation of 1,3-Disubstituted Imidazolidine-2,4,5-triones as Inhibitors of Pyruvate Carboxylase. [PDF]

ACS Med Chem Lett
Schneider NO, Gilreath K, Henriksen NM, Donaldson WA, Chaudhury S, St Maurice M.   +5 more
europepmc   +1 more source

Glucagon promotes increased hepatic mitochondrial oxidation and pyruvate carboxylase flux in humans with fatty liver disease. [PDF]

Cell Metab
Petersen KF, Dufour S, Mehal WZ, Shulman GI.   +3 more
europepmc   +1 more source

The mitochondrial enzyme pyruvate carboxylase restricts pancreatic β-cell senescence by blocking p53 activation. [PDF]

Proc Natl Acad Sci U S A
Yang Y, Wang B, Dong H, Lin H, Yuen-Man Ho M, Hu K, Zhang N, Ma J, Xie R, Cheng KK, Li X.   +10 more
europepmc   +1 more source

Metabolic profiling of glioblastoma stem cells reveals pyruvate carboxylase as a critical survival factor and potential therapeutic target. [PDF]

Neuro Oncol
Renoult O, Laurent-Blond M, Awada H, Oliver L, Joalland N, Croyal M, Paris F, Gratas C, Pecqueur C.   +8 more
europepmc   +1 more source

Pyruvate carboxylase deficiency type C; variable presentation and beneficial effect of triheptanoin. [PDF]

JIMD Rep
Bernhardt I, Van Dorp L, Dixon M, McSweeney M, Gan C, Baruteau J, Chakrapani A.   +6 more
europepmc   +1 more source