Results 131 to 140 of about 27,529 (245)

Stearoyl‐CoA Desaturase‐1 Drives Tumor Growth by Interacting With Histone Deacetylase‐2 and Deacetylating Nucleophosmin‐1

MedComm, Volume 7, Issue 6, June 2026.
Hypoxia induces SCD1 and PLIN2 to drive lipid droplet‐dependent metabolic adaptation in cancer cells. PLIN2 supports survival under stress, whereas SCD1 promotes proliferation upon reoxygenation and remodels the acetylome via HDAC2‐mediated NPM1 deacetylation and destabilization.
Coline Wery, Laetitia Montero‐Ruiz, Eric Bonneil, Mohammad Farran, Robin Jehay, Quentin Herrara Garfia, Gregory Fettweis, Silvia Blacher, Charles Pottier, Gael Cobraiville, Yasmine Boumahd, Olivier Peulen, Agnès Noël, Franck Dequiedt, Marianne Fillet, Nor Eddine Sounni   +15 more
wiley   +1 more source

Does Gum Arabic Alter Gene Expression? Diabetic and Obesity as Models: A Mini Review

Modern Agriculture, Volume 4, Issue 1, June 2026.
Gum Arabic (GA) modulates obesity‐ and diabetes‐related gene expression, reducing pro‐inflammatory cytokines (IL‐6, TNF‐α, IL‐1β) and increasing IL‐10. GA elevates pAMPK, pACC, and GLP‐1 while decreasing FASN and leptin, indicating improved energy and lipid metabolism. Oxidative stress markers (SOD, GPx, CAT) rise with GA, alongside increased GLUT3 and
Saber Y. Adam, Taha Hussein Musa, Hassan Hussein Musa, Ahmed A. Saleh, Abdelkareem A. Ahmed   +4 more
wiley   +1 more source

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

Pyruvate Carboxylase Deficiency [PDF]

, 2020
William L. Nyhan, Georg F. Hoffmann, Aida I. Al-Aqeel, Bruce A. Barshop   +3 more
  +5 more sources

The presence of pyruvate carboxylase in the human brain and its role in the survival of cultured human astrocytes. [PDF]

Physiol Res, 2023
Gondáš E, Kráľová Trančíková A, Šofranko J, Majerová P, Lučanský V, Dohál M, Kováč A, Murín R.   +7 more
europepmc   +1 more source

Pyruvate Carboxylase

Journal of Biological Chemistry, 1963
D. Bruce Keech, Merton F. Utter
openaire   +1 more source

Target‐site and non‐target‐site mechanisms confer multiple herbicide resistance in waterhemp (Amaranthus tuberculatus) accessions from Wisconsin

Pest Management Science, Volume 82, Issue 6, Page 5695-5706, June 2026.
The A101 accession is the first confirmed case of hydroxyphenyl pyruvate dioxygenase resistance in Amaranthus tuberculatus in Wisconsin, and the first report of P450s associated with atrazine resistance in A. tuberculatus globally. Abstract BACKGROUND A preliminary screening identified a multiple herbicide‐resistant waterhemp, Amaranthus tuberculatus ...
Felipe A. Faleco, Isabel S. Werle, Alexander J. Lopez, Damilola A. Raiyemo, Patrick J. Tranel, Jed B. Colquhoun, Mark J. Renz, David E. Stoltenberg, Rodrigo Werle   +8 more
wiley   +1 more source

Causal Relationship Between Mitochondrial Characteristics and Inflammatory Bowel Disease and Its Subtypes: Evidence for Mendelian Randomization

JGH Open
Objective The research was designed to explore the causal relationship between the changing landscape of 63 mitochondrial proteins and inflammatory bowel disease (IBD) by Mendelian randomization.
Yichen Cai, Hancheng Fan, Jianmin Zhao, Guoxiang Fu   +3 more
doaj   +1 more source

Clinical, biochemical and molecular characterization of 12 patients with pyruvate carboxylase deficiency treated with triheptanoin. [PDF]

Mol Genet Metab, 2023
Lasio MLD, Leshinski AC, Ducich NH, Flore LA, Lehman A, Shur N, Jayakar PB, Hainline BE, Basinger AA, Wilson WG, Diaz GA, Erbe RW, Koeberl DD, Vockley J, Bedoyan JK.   +14 more
europepmc   +1 more source

Pyruvate Carboxylase

Journal of Biological Chemistry, 1966
Michael C. Scrutton, Merton F. Utter, Albert S. Mildvan   +2 more
openaire   +1 more source