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Pyruvate Carboxylase and Pyruvate Dehydrogenase Deficiency
2014Pyruvate carboxylase and pyruvate dehydrogenase deficiency are the most common disorders in pyruvate metabolism and almost always affect the central nervous system. The severity and the clinical phenotypes vary, with a range from overwhelming neonatal lactic acidosis and early death to milder presentations.
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Roles of pyruvate carboxylase in human diseases: from diabetes to cancers and infection
Journal of molecular medicine, 2018Udom Lao-On, P. Attwood, S. Jitrapakdee
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Bioprocess and biosystems engineering (Print), 2016
Mei-Juan Tan +4 more
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Mei-Juan Tan +4 more
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Structural basis for regulation of human acetyl-CoA carboxylase
Nature, 2018Moritz Hunkeler +2 more
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Pyruvate carboxylase activity in lymphoblasts
Journal of Inherited Metabolic Disease, 1982G, Takada +4 more
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A vitamin K-dependent carboxylase orthologue is involved in antibiotic biosynthesis
Nature Catalysis, 2018Ying Zhuo, Michael Winn, Yingxin Zhang
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