Results 51 to 60 of about 13,556 (147)

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1192-1203, June 2026.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt, Polona Le Quesne Stabej, Claire Hart, Mark De Hora, Sarah Hulley, Mark Anderson, Harry G. Leitch, Hugh Lemonde, Bryony Ryder, James Davison   +9 more
wiley   +1 more source

Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of beta-oxidation in insulin secretion [PDF]

, 2001
A female infant of nonconsanguineous Indian parents presented at 4 months with a hypoglycemic convulsion. Further episodes of hypoketotic hypoglycemia were associated with inappropriately elevated plasma insulin concentrations.
Aynsley-Green, A, Berger, R, Clayton, PT, Datta, V, Eaton, S, Edginton, M, Hussain, K, Krywawych, S, Malingre, HEM, van den Berg, IET   +9 more
core  

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

Modulation of Neurogenesis through the Promotion of Energy Production Activity Is behind the Antidepressant-Like Effect of Colonial Green Alga, Botryococcus braunii [PDF]

, 2017
Algae have been recognized as important resources providing functional components due to their capacity to exert beneficial effects on health. Therefore, there is increasing interest in investigating the biological activity of algae.
Demura Mikihide, Isoda Hiroko, Othman Mahmoud B., Sasaki Kazunori, Watanabe Makoto, 佐々木 一憲, 礒田 博子   +6 more
core   +1 more source

Association mapping for hop cone chemistry and morphology identifies natural beneficial allele stacks

The Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Efforts are underway to increase the efficiency and precision of selection hop (Humulus lupulus L.) breeding using genomics. Little is known, however, about the genetic control of important traits like α‐and β‐acids contents, oil content, and cone morphological characteristics, all of which play an important role in determining the utility and
Shaun J. Clare, Peter Schmuker, Kayla Altendorf   +2 more
wiley   +1 more source

Characterisation of aerotolerant forms of a robust chicken colonizing Campylobacter coli [PDF]

, 2017
Campylobacter contaminated poultry meat is a major source of human foodborne illness. Campylobacter coli strain OR12 is a robust colonizer of chickens that was previously shown to outcompete and displace other Campylobacter strains from the chicken’s ...
Al-Haideri, Atack, Atack, Atack, Benesch, Blaser, Bleumink-Pluym, Bolton, Bronnec, Brown, Bury-Moné, Chynoweth, Conlan, Douidah, EFSA, EFSA, EFSA, El-Shibiny, El-Shibiny, El-Shibiny, El-Shibiny, Flint, Flint, Flint, Fouts, Garénaux, Gaynor, Ghaffar, Gillespie, Goss, Guerry, Gundogdu, Hermans, Hobb, Hwang, Imlay, Inatsuka, Jacobs-Reitsma, Jeanson, John, Jones, Kaakoush, Loc Carrillo, McNally, Miles, Miller, Moreno, Oh, O’Brien, Palyada, Parkhill, PHE, Purdy, Reyrolle, Ribot, Rodrigues, Rutherford, Scott, Sheppard, Smith, Speegle, Stahl, Stern, Takamiya, Tam, Theoret, van Gerwe, Vegge, Velayudhan, Velayudhan, Wagley, WHO, Wilson   +72 more
core   +1 more source

Next‐Generation Sustainable Food Production Through Integrative Biotechnology, AI, and Climate‐Resilient Innovations

Food and Energy Security, Volume 15, Issue 3, May/June 2026.
ABSTRACT By 2050, the global population is projected to reach ~10 billion, leading to 50% increase in food demand. This growth will place immense pressure on agricultural systems that are already struggling with the impacts of climate change and resource depletion.
Chaquayla Katam, Hajra Maqsood, Brooke Bucci, Sixue Chen   +3 more
wiley   +1 more source

Molecular mechanism of dominant expression in 3-methylcrotonyl-CoA carboxylase deficiency [PDF]

, 2018
Summary: Most enzyme deficiencies in humans are inherited as autosomal recessive traits. The term dominant negative is applied to mutant alleles in which a mutant protein interferes in one way or another with the function of the normal protein being ...
Baumgartner, M.
core  

The biochemical basis of disease [PDF]

, 2018
Understanding Biochemistry is an essential online resource for post-16 students, teachers and undergraduates, providing up-to-date overviews of key concepts in biochemistry and molecular biosciences.
Ahlqvist, Alastair J. Barr, Arteaga, Baynes, Cancer Research UK 2018, Carey, Christakos, Clemens, Diabetes UK - The Cost of Diabetes, Druker, Feingold, Graham, Grove, Hanahan, Hanahan, Hantschel, Heinecke, IDF Diabetes Atlas - 8th Edition, Kagnoff, Kamangar, Keys, Knudson, Kumar, Leiva, Maher, Mann, Masters, McLannahan, NHS - Do I need vitamin supplements, NIH - AIDS Information 2018, NIH - Office of dietary supplements, NIH Genetics Home Reference - Phenylketonurea 2018, Osna, Papaemmanuil, Pecorino, Ramagopalan, Rang, Reilly, Rich, Ridaura, Samuel, Schulz, Seeley, The Cancer Genome Atlas 2018, Wang, Watts, Weinberg, Wilen, World Health Organization, World Health Organization - Cancer 2018, World Health Organization - Cholera 2018, World Health Organization - HIV/AIDS 2018, Yarden   +52 more
core   +1 more source

Liver Fibrosis: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 5, May 2026.
We systematically summarized the etiologies, diagnostic approaches, and pathogenic mechanisms of liver fibrosis. Also, the therapeutic interventions for liver fibrosis were systematically classified into two main categories: etiological treatment and mechanism‐based antifibrotic therapies.
Jiaorong Qu, Wenqing Qin, Minghang Dong, Zhi Ma, Si Li, Runping Liu, Ranyun Chen, Changmeng Li, Xiaojiaoyang Li   +8 more
wiley   +1 more source