Results 51 to 60 of about 6,583 (140)
, 2002 Human pyruvate carboxylase (PC) deficiency is an autosomal recessive disorder that ranges in severity from a benign (Type C) to a simple (Type A) to a severe (Type B) phenotype.
Carbone, Mary Anna
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Mitochondrial disorders in childhood : from general characteristics to new aspects [PDF]
, 2007 Consultable des del TDXTítol obtingut de la portada digitalitzadaLas enfermedades mitocondriales pueden ser englobadas dentro de las enfermedades raras de la edad pediátrica.
García-Cazorla, Angels +1 more
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Fatty Acid Metabolism in Health and Cancer: From Fundamental Mechanisms to Therapeutic Application
MedComm, Volume 7, Issue 6, June 2026.The modulation of the TME by fatty acid metabolism primarily occurs through four key pathways: inflammation regulation, signal transduction, translation to TME, and oxidative stress. ABSTRACT Fatty acid metabolism (FAM) plays a vital role in maintaining health by supporting energy production, cellular structure, and signaling processes.
Na Hang +12 more
wiley +1 more source
Does Gum Arabic Alter Gene Expression? Diabetic and Obesity as Models: A Mini Review
Modern Agriculture, Volume 4, Issue 1, June 2026.Gum Arabic (GA) modulates obesity‐ and diabetes‐related gene expression, reducing pro‐inflammatory cytokines (IL‐6, TNF‐α, IL‐1β) and increasing IL‐10. GA elevates pAMPK, pACC, and GLP‐1 while decreasing FASN and leptin, indicating improved energy and lipid metabolism. Oxidative stress markers (SOD, GPx, CAT) rise with GA, alongside increased GLUT3 and
Saber Y. Adam +4 more
wiley +1 more source
Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives
MedComm – Oncology, Volume 5, Issue 2, June 2026.Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang +14 more
wiley +1 more source
The critical role of oxalate in the liver-kidney axis and its effect on glucose metabolism
Glucose metabolism is a highly regulated and conserved pathway orchestrated by several factors like hormones, nutritional state and enzymes. The organs, which are responsible to maintain normal blood glucose levels are the liver the kidney.
Gabrys, Philipp
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Characterisation of human holocarboxylase synthetase. [PDF]
, 2009 Biotin (also known as vitamin H or vitamin B7) is an essential micronutrient that is utilised by all living organisms. A key enzyme in the lifecycle of biotin is biotin protein ligase (BPL).
Bailey, Lisa Marie
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The Plant Genome, Volume 19, Issue 2, June 2026.Abstract Efforts are underway to increase the efficiency and precision of selection hop (Humulus lupulus L.) breeding using genomics. Little is known, however, about the genetic control of important traits like α‐and β‐acids contents, oil content, and cone morphological characteristics, all of which play an important role in determining the utility and
Shaun J. Clare +2 more
wiley +1 more source
The use of a genetic strategy to study the role of modulation of oxidative stress by uncoupling proteins 2 and 3 in the pathogenesis of Type 2 Diabetes [PDF]
, 2008 Mitochondrial dysfunction has been implicated in the early pathogenesis of Type 2 Diabetes. The uncoupling proteins 2 and 3 are mitochondrial proteins found in man that have been implicated in protecting mammals from the effects of over-nutrition ...
Gable, D R, Gable, D.R.
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, 2021 Mitochondrial dysfunction may contribute to conditions and diseases such as weight gain, obesity, insulin resistance and type 2 diabetes (Christe et al., 2013; C. Yang et al., 2012).
Fokin, Andrej,
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