Results 61 to 70 of about 6,583 (140)

Third Generation Genome Sequencing of the Endobacterium Corynebacterium kroppenstedtii subsp. demodicis Reveals Details of Its Microbe‐Host‐Interaction With the Most Complex Human Commensal, Demodex folliculorum

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 3, June 2026.
The symbiotic interaction between Demodex folliculorum and Corynebacterium kroppenstedtii subsp. demodicis. Created by the author based on genomic and functional analyses presented in this work. The tripartite interaction between the human host, the mite Demodex folliculorum, and its endosymbiont Corynebacterium kroppenstedtii subsp. demodicis.
T. Steegmüller   +6 more
wiley   +1 more source

Cannabidiol and cannabigerol ameliorate steatotic liver disease via phosphocreatine buffering and lysosomal restoration

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 12, Page 3173-3194, June 2026.
Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová   +12 more
wiley   +1 more source

Multifunctional Role of Mitochondrial Fatty Acid Oxidation in Cancer Immunotherapy and Aging

open access: yesCancer Science, Volume 117, Issue 6, Page 1554-1565, June 2026.
Recent studies have highlighted the complex interplay between tumor immunity, aging, and inflammation. Mitochondrial FAO is a major hub of this physiological interplay. ABSTRACT Recent studies have demonstrated the intricate relationship between tumor immunity, aging, and inflammation.
Koji Kitaoka   +4 more
wiley   +1 more source

Energetic stress in combination with impaired fatty acid oxidation induces sequestration of CoA and adaptation of CoA metabolism

open access: yesThe FEBS Journal, Volume 293, Issue 12, Page 3565-3587, June 2026.
Computational modelling and in vitro liver cell experiments indicate that medium‐chain acyl‐CoA dehydrogenase (MCAD) deficiency causes an accumulation of (especially medium‐chain) acyl‐CoAs at the cost of free CoA (CoASH). A substantial decrease in CoASH impairs flux through many pathways essential for energy homeostasis.
Ligia Akemi Kiyuna   +17 more
wiley   +1 more source

Energy Stress‐Induced Neuroprotection Against Ferroptosis in Dopaminergic Neurons

open access: yesJournal of Neurochemistry, Volume 170, Issue 6, June 2026.
Energy stress via glucose deprivation activates AMPK and protects dopaminergic neurons from ferroptosis by limiting lipid peroxidation. In contrast, glucose availability supports ferroptosis through oxidizable lipid pools. ABSTRACT Ferroptosis, an iron‐dependent form of regulated necrosis, is implicated in the pathogenesis of Parkinson's disease (PD ...
Aurélie Jonneaux   +8 more
wiley   +1 more source

Microscale characterisation of a manufacturing route for lentiviral vectors

open access: yes, 2015
Lentiviral vectors used in clinical trials are currently produced by transient transfection of adherent human embryonic kidney (HEK)293(T) cells. However, this approach is not scalable and for commercialisation the development of alternative strategies ...
Guy, HM
core  

Regulation of gluconeogenesis in type 2 diabetes mellitus: An investigation of the role of corticosteroids?

open access: yes, 2012
PhDType 2 diabetes mellitus (T2DM) is a complex disease involving various physiological factors, hormones and metabolites. Over expression of key gluconeogenic enzymes, such as PEPCK, cause features of T2DM including obesity and insulin resistance ...
Nayuni, Nanda Kishore Babu
core  

Inorganic carbon acquisition in Palmaria palmata (Rhodophyta)

open access: yes, 2010
PhDDIC acquisition mechanisms and the use of DIC in photosynthesis were examined in the temperate red macroalga, Palmaria palmata (Linnaeus) O. Kuntze.
Hill, Gregg
core  

고농도 포도당과 Palmitate에 의한 INS-1 베타세포의 세포사 기작 연구

open access: yes, 2008
Type 2 diabetes is considered to be in most cases a polygenic disease with a strong involvement of environmental factors, such as diet and exercise. Chronic exposure of high glucose and free fatty acids (FFAs) induces pancreatic beta cell dysfunction and
이, 연정
core  

Conventional and deep-litter pig production systems: the effects on fat deposition and distribution in growing female large white X landrace pigs

open access: yes, 2008
Minimising variability in carcass quality to better meet market specifications is a priority for Australian pig producers, however issues with variability in carcass fat distribution have recently been raised, particularly in the belly primal.
Trezona-Murray, Megan
core  

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