Results 61 to 70 of about 13,556 (147)
Coronatine-insensitive 1 (COI1) mediates transcriptional responses of Arabidopsis thaliana to external potassium supply [PDF]
, 2010 The ability to adjust growth and development to the availability of mineral nutrients in the soil is an essential life skill of plants but the underlying signaling pathways are poorly understood.Abe, Amtmann, Amtmann, Amtmann, Amtmann, Amtmann, Amtmann, Amtmann, Armengaud, Armengaud, Ashley, Balbi, Bednarek, Bolstad, Breitling, Breitling, Cao, Chung, Creelman, Devoto, Devoto, Dobermann, Epstein, Evans, Geisler, He, Hull, Jung, Kafkafi, Kim, Laegreid, Li, Maathuis, Maathuis, Marschner, Mikkelsen, Munemasa, Nakano, Okushima, Oria-Hernandez, Otterhag, Pandey, Penninckx, Perez-Amador, Reinbothe, Reymond, Ross, Schachtman, Shin, Shin, Sparla, Staswick, Staswick, Staswick, Sun, Syers, Thines, Tschoep, Vernoud, Véry, Walker, Westphal, Xie, Xu, Yamaguchi-Shinozaki, Yan, Zimmermann +66 morecore +6 more sourcesPerspectives for Advancing Biotechnological Succinic Acid Production
Microbial Biotechnology, Volume 19, Issue 5, May 2026.Succinic acid is an important molecule for sustainable chemical manufacturing, but its industrial production faces high costs and sustainability challenges, which are linked to feedstocks and excessive acid/base consumption. This opinion explores production routes based on next‐generation feedstocks and low‐pH fermentations to inspire novel cost ...Christoph Gunkel, Bastian Blombachwiley +1 more sourceKetogenesis prevents diet-induced fatty liver injury and hyperglycemia [PDF]
, 2014 Nonalcoholic fatty liver disease (NAFLD) spectrum disorders affect approximately 1 billion individuals worldwide. However, the drivers of progressive steatohepatitis remain incompletely defined.Baris Ercal, Befroy, Chen, D. André d’Avignon, David G. Cotter, Dennis J. Dietzen, Elizabeth M. Brunt, Gary J. Patti, Hegardt, Jamison M. Leid, Jitrapakdee, Kanehisa, Mark J. Graham, Peter A. Crawford, Robinson, Sengupta, Serviddio, Soeters, Tautenhahn, Thumelin, Thurston, Williamson, Williamson, Williamson, Williamson, Wolf, Xiaojing Huang +26 morecore +2 more sourcesCitrate‐Dependent Activation of Acetyl CoA Carboxylase Promotes Renal Lipid Accumulation in a Rat Model of Chronic Kidney Disease
Acta Physiologica, Volume 242, Issue 5, May 2026.ABSTRACT Background
Abnormal accumulation of lipids within the kidney contributes to the progression of chronic kidney disease, but the underlying metabolic mechanisms remain unclear. Citrate is a central metabolite in cellular energy regulation and is frequently elevated in advanced kidney disease, yet its impact on renal lipid metabolism has not been Marta Sanz‐Gómez, Beatriz Linillos‐Pradillo, Rubén Fernández de la Rosa, Isabel Aránguez, Reinhold Kreutz, Antonia García, Coral Barbas, Adrián Plaza, María S. Fernández‐Alfonso +8 morewiley +1 more sourceTherapeutic Effect of Targeting Branched-Chain Amino Acid Catabolic Flux in Pressure-Overload Induced Heart Failure. [PDF]
, 2019 Background Branched-chain amino acid (BCAA) catabolic defect is an emerging metabolic hallmark in failing hearts in human and animal models. The therapeutic impact of targeting BCAA catabolic flux under pathological conditions remains understudied ...Chen, Mengping, Chuang, David T, Gao, Chen, Ren, Shuxun, Sun, Haipeng, Wang, Menglong, Wang, Yibin, Wynn, R Max, Yu, Jiayu +8 morecore +1 more sourceTargeting cancer metabolism: a therapeutic window opens [PDF]
, 2011 Genetic events in cancer activate signalling pathways that alter cell metabolism. Clinical evidence has linked cell metabolism with cancer outcomes. Together, these observations have raised interest in targeting metabolic enzymes for cancer therapy, but ...A Clementi, A Dimitrakopoulou-Strauss, A Garten, A Le, A Wolf, A Yalcin, AM Groves, AP Halestrap, AP Pereira da Silva, AS Marsin, B Clem, B Dwarakanath, BA Chabner, BK Mohanti, BR Landau, C Algire, C Derst, C Garcia-Echeverria, C Yang, CH Holdsworth, CM Murray, CS Potten, CV Dang, D Hanahan, D Singh, DA Rew, DA Tennant, DA Tennant, DE Bauer, DK Nomura, DR Wise, DW Parsons, E Eschwege, E Furuta, ED Michelakis, EE Calle, EE Calle, ER Mardis, ES Burgos, G Hatzivassiliou, G Marcucci, G Ollenschlager, GA Spoden, GL Semenza, H Linardou, H Shim, H Yan, HA Hirsch, HR Christofk, HR Christofk, I Maestu, I Papandreou, J Kurhanewicz, J Luo, J Yun, JA Engelman, JA Engelman, JA Menendez, JA Meyerhardt, Jason W Locasale, JB Wang, JD Broome, JG Kidd, JK Jiang, JM Brown, JM Evans, JW Kim, JW Locasale, K Brindle, K Chen, K Duvel, K Holen, K Hosono, K Zaugg, KE Wellen, KH Vousden, KM Kennedy, KS Dimmer, L Dang, L Galluzzi, L Tallal, LG Boros, M Buzzai, M Hasmann, M Ko, M Ookhtens, M Pittelli, M Pollak, M Pollak, M Tahiliani, M Takenaka, M Yuneva, MA Weiser, Matthew G. Vander Heiden, MB Boxer, MB Tessem, MC Li, ME Figueroa, MG Vander Heiden, MG Vander Heiden, MG Vander Heiden, MJ Evans, MJ Holness, MJ Ovens, MJ Seltzer, ML Macheda, ML Tainter, MR Stratton, MS Ardawi, MY El-Mir, N El Mjiyad, N Jaffe, N Normanno, NP Curthoys, NP Manes, NY Kalaany, O Kaplan, P Cocco, P Gao, P Sonveaux, P Thirion, PS Ward, R Chowdhury, R Flavin, R Zhou, R Zoncu, RA Cairns, RA Larson, RB Robey, RB Scott, RE Neuman, RG Jones, RG Maki, RG Verhaak, Richard Possemato, RJ Deberardinis, RJ DeBerardinis, RJ Shaw, RJ Shaw, RL Aft, RM Memmott, S Ben-Haim, S Bonnet, S Bruzzone, S Farber, S Farber, S Gross, S Jiralerspong, S Mazurek, S Stacchiotti, S Telang, SH Jee, SJ Bach, SL Bowker, SM Gallagher, SP Mathupala, T Atsumi, T Cheng, T Shlomi, T Yamamoto, TS Yang, V Chajes, VR Fantin, VT DeVita, W Hu, W Kuo, W Xu, WG Kaelin Jr, Y Kumei, Y Ni, Y Yu, YH Ko +171 morecore +1 more sourceLack of liver glycogen causes hepatic insulin resistance and steatosis in mice [PDF]
, 2017 Disruption of the Gys2 gene encoding the liver isoform of glycogen synthase generates a mouse strain (LGSKO) that almost completely lacks hepatic glycogen, has impaired glucose disposal, and is pre-disposed to entering the fasted state.DePaoli-Roach, Anna A., Irimia, Jose M., Meyer, Catalina M., Morral, Nuria, Roach, Peter J., Segvich, Dyann M., Surendran, Sneha +6 morecore +1 more sourceBiotin Status of Epileptics [PDF]
, 1985 Achuta Murthy P. N., Berlit P., Blass J. P., Bonjour J.-P., Bonjour J.-P., Caspers H., Frigg M., Ghatak N. R., Glaser G. H., Iivanainen M., Johnston D., Krause K.-H., Krause K.-H., Krause K.-H., Meinardi H., Mock D. M., Munoz-Garcia D., Noll F., Patel M. S., Paulsen E. P., Reynolds E. H., Sander J. E., Schmidt D., Scorn D., Selhorst J. B., Sweetman L., Sydenstricker V. P., Thoene J., Vivo D. C., Watanabe T., Wolf B., Woodbury D. M., Woodbury D. M., Woodbury D. M. +33 morecore +1 more source
