Results 91 to 100 of about 145,153 (320)

Mutual-Information Based Optimal Experimental Design for Hyperpolarized $^{13}$C-Pyruvate MRI [PDF]

open access: yesarXiv, 2022
A key parameter of interest recovered from hyperpolarized (HP) MRI measurements is the apparent pyruvate-to-lactate exchange rate, $k_{PL}$, for measuring tumor metabolism. This manuscript presents an information-theory-based optimal experimental design (OED) approach that minimizes the uncertainty in the rate parameter, $k_{PL}$, recovered from HP-MRI
arxiv  

Formation of Aliphatic and Aromatic α-Hydroxy Ketones by Zygosaccharomyces bisporus [PDF]

open access: yes, 2000
The wild-type yeast strain Zygosaccharomyces bisporus CBS 702 produced a-hydroxy-ketones (acyloins) from amino acid precursors after transamination to the corresponding 2-oxo acids.
Berger, Ralf Günter   +2 more
core   +1 more source

Chinese herbal medicine‐derived extracellular vesicle‐like particles: Therapeutic potential and future research approaches

open access: yesInterdisciplinary Medicine, EarlyView.
This article evaluates the therapeutic potential of extracellular vesicle‐like particles derived from Chinese herbal medicine (CHM‐EVLP) for a range of diseases. It underscores the significance of traditional Chinese medicine in the development of innovative formulations.
Ying‐qi Cao   +6 more
wiley   +1 more source

Substrate Activation Of Yeast Pyruvate Decarboxylases

open access: yes, 2007
Short presentation for winning a poster award (Enzymes in motion - substrate activation of yeast pyruvate decarboxylases I. Crystal structures, 10.5281/zenodo.1313834) during the 7th international conference on mechanism and physiology of thiamine, Wittenberg, Germany, 05/29/2008-06/01/2008 Held on 06/01/2018, 11.25 am, https://dechema.de ...
openaire   +3 more sources

125th anniversary review: fuel alcohol: current production and future challenges [PDF]

open access: yes, 2011
Global research and industrial development of liquid transportation biofuels are moving at a rapid pace. This is mainly due to the significant roles played by biofuels in decarbonising our future energy needs, since they act to mitigate the deleterious ...
Walker, Graeme M.
core   +2 more sources

The role of gut microbiota‐derived metabolites in neuroinflammation

open access: yesNeuroprotection, EarlyView.
Gut microbiota‐derived metabolites accumulate in the brain, activating or inhibiting microglia and astrocytes, which affects neuroinflammatory progression. The gut microbiota converts the diet into a variety of metabolites, including bile acid, trimethylamine N‑oxide (TMAO), and indole.
Lingjie Mu, Yijie Wang
wiley   +1 more source

Pyruvate Decarboxylase Activity Assay in situ of Different Industrial Yeast Strains

open access: yesFood Technology and Biotechnology, 2009
Cytoplasmic pyruvate decarboxylase (PDC, EC 4.1.1.1) is one of the key enzymes of yeast fermentative metabolism. PDC is the first enzyme which, under anaerobic conditions, leads to decarboxylation of pyruvate with acetaldehyde as the end product. The aim
Dorota Kręgiel   +2 more
doaj  

Fecal Metaproteomics as a Tool to Monitor Functional Modifications Induced in the Gut Microbiota by Ketogenic Diet: A Case Study

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Metaproteomics is a valuable approach to characterize the biological functions involved in the gut microbiota (GM) response to dietary interventions. Ketogenic diets (KDs) are very effective in controlling seizure severity and frequency in drug‐resistant epilepsy (DRE) and in the weight loss management in obese/overweight individuals.
Alessandro Tanca   +3 more
wiley   +1 more source

A pyruvate decarboxylase gene fromAspergillus parasiticus [PDF]

open access: yesFEMS Microbiology Letters, 1994
A gene encoding a putative pyruvate decarboxylase (EC 4.1.1.1) was isolated from a genomic library of the filamentous fungus Aspergillus parasiticus strain SU-1. The deduced amino acid sequence showed 37% homology to PDC1 from Saccharomyces cerevisiae. Although A.
Vicente Sanchis   +5 more
openaire   +2 more sources

Incorporating expression data in metabolic modeling: a case study of lactate dehydrogenase [PDF]

open access: yesJ Theor Biol 240: 464-474 (2006), 2005
Integrating biological information from different sources to understand cellular processes is an important problem in systems biology. We use data from mRNA expression arrays and chemical kinetics to formulate a metabolic model relevant to K562 erythroleukemia cells. MAP kinase pathway activation alters the expression of metabolic enzymes in K562 cells.
arxiv   +1 more source

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