Results 51 to 60 of about 145,153 (320)

Phenotypic landscape inference reveals multiple evolutionary paths to C$_4$ photosynthesis [PDF]

open access: yes, 2013
C$_4$ photosynthesis has independently evolved from the ancestral C$_3$ pathway in at least 60 plant lineages, but, as with other complex traits, how it evolved is unclear.
Abramoff   +88 more
core   +3 more sources

Decarboxylation of Pyruvate to Acetaldehyde for Ethanol Production by Hyperthermophiles

open access: yesBiomolecules, 2013
Pyruvate decarboxylase (PDC encoded by pdc) is a thiamine pyrophosphate (TPP)-containing enzyme responsible for the conversion of pyruvate to acetaldehyde in many mesophilic organisms.
Mohammad S. Eram, Kesen Ma
doaj   +1 more source

Metabolism within the tumor microenvironment and its implication on cancer progression: an ongoing therapeutic target [PDF]

open access: yes, 2018
Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor metabolism is again in the spotlight of cancer research. Many studies have been carried out and many possible therapies have been developed in the last years.
Abdel-Aziz   +431 more
core   +2 more sources

The impact of RNA binding proteins and the associated long non-coding RNAs in the TCA cycle on cancer pathogenesis

open access: yesRNA Biology, 2023
The tricarboxylic acid (TCA) cycle is a central route for generating cellular energy and precursors for biosynthetic pathways. Emerging evidences have shown that the aberrations of metabolic enzymes which affect the integrity of TCA cycle are implicated ...
Tao Shen   +4 more
doaj   +1 more source

Potential therapeutic use of the ketogenic diet in autism spectrum disorders. [PDF]

open access: yes, 2014
The ketogenic diet (KGD) has been recognized as an effective treatment for individuals with glucose transporter 1 (GLUT1) and pyruvate dehydrogenase (PDH) deficiencies as well as with epilepsy.
Dueñas, Nadia   +2 more
core   +1 more source

Role of the glassy dynamics and thermal mixing in the dynamic nuclear polarization and relaxation mechanisms of pyruvic acid [PDF]

open access: yesPhys. Chem. Chem. Phys., 2014,16, 27025-27036, 2014
The temperature dependence of $^1$H and $^{13}$C nuclear spin-lattice relaxation rate $1/T_1$ has been studied in the 1.6 K - 4.2 K temperature range in pure pyruvic acid and in pyruvic acid containing trityl radicals at a concentration of 15 mM. The temperature dependence of $1/T_1$ is found to follow a quadratic power law for both nuclei in the two ...
arxiv   +1 more source

Effect of Respiratory Growth on the Metabolite Production and Stress Robustness of Lactobacillus casei N87 Cultivated in Cheese Whey Permeate Medium

open access: yesFrontiers in Microbiology, 2019
Cheese whey permeate (WP) is a low-cost feedstock used for the production of biomass and metabolites from several lactic acid bacteria (LAB) strains. In this study, Lactobacillus casei N87 was cultivated in an optimized WP medium (WPM) to evaluate the ...
Annamaria Ricciardi   +5 more
doaj   +1 more source

Elimination of aromatic fusel alcohols as by-products of Saccharomyces cerevisiae strains engineered for phenylpropanoid production by 2-oxo-acid decarboxylase replacement

open access: yesMetabolic Engineering Communications, 2021
Engineered strains of the yeast Saccharomyces cerevisiae are intensively studied as production platforms for aromatic compounds such as hydroxycinnamic acids, stilbenoids and flavonoids.
Else-Jasmijn Hassing   +6 more
doaj  

Current Methods for Hyperpolarized [1-13C]pyruvate MRI Human Studies [PDF]

open access: yes, 2023
MRI with hyperpolarized (HP) 13C agents, also known as HP 13C MRI, can measure processes such as localized metabolism that is altered in numerous cancers, liver, heart, kidney diseases, and more. It has been translated into human studies during the past 10 years, with recent rapid growth in studies largely based on increasing availability of ...
arxiv   +1 more source

Transcriptome Analysis Reveals Genes Associated with Flooding Tolerance in Mulberry Plants

open access: yesLife, 2023
Mulberry (Morus alba), a widely distributed economic plant, can withstand long-term flooding stress. However, the regulatory gene network underlying this tolerance is unknown.
Jingtao Hu   +8 more
doaj   +1 more source

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