Results 81 to 90 of about 933 (184)

Cytosolic re-localization and optimization of valine synthesis and catabolism enables inseased isobutanol production with the yeast Saccharomyces cerevisiae

open access: yesBiotechnology for Biofuels, 2012
Background The branched chain alcohol isobutanol exhibits superior physicochemical properties as an alternative biofuel. The yeast Saccharomyces cerevisiae naturally produces low amounts of isobutanol as a by-product during fermentations, resulting from ...
Brat Dawid   +4 more
doaj   +1 more source

Hypotaurine Reduces Glucose‐Mediated Vascular Calcification

open access: yesActa Physiologica, Volume 241, Issue 8, August 2025.
ABSTRACT Aim Vascular calcification (VC), a characteristic feature of peripheral artery disease in patients with diabetes and chronic kidney disease, has been associated with poor prognosis. We hypothesize that hyperglycemia drives VC through alterations in metabolomic and transcriptomic profiles. Methods Human coronary artery smooth muscle cells (SMCs)
Marina A. Heuschkel   +9 more
wiley   +1 more source

Elimination of hepatocyte‐derived DPP4 downregulates cardiac immune‐ and collagen‐related genes but does not alter cardiac function in aged male mice

open access: yesPhysiological Reports, Volume 13, Issue 15, August 2025.
Abstract The association between metabolic dysfunction–associated steatotic liver disease (MASLD) and cardiovascular disease is well characterized; however, the underlying mechanism is incompletely understood. Interestingly, hepatocyte‐specific silencing of dipeptidyl peptidase 4 (DPP4) prevents liver fibrosis and adipose tissue inflammation; however ...
Natasha A. Trzaskalski   +8 more
wiley   +1 more source

Enzymes In Motion Substrate Activation Of Pyruvate Decarboxylases

open access: yes, 2007
Hasylab Ann. Rep. 2007, 367-368 This report illustrates global structural changes of yeast pyruvate decarboxylases after the addition of substrates and substrate surrogates. We used a SAXS based assay for our experiments.
Kutter, Steffen   +3 more
openaire   +2 more sources

Waterlogging-induced changes in fermentative metabolism in roots and nodules of soybean genotypes

open access: yesScientia Agricola, 2014
Waterlogging blocks the oxygen supply to the root system which inhibits respiration, and greatly reduces the energy status of cells that affect important metabolic processes.
Junior Borella   +4 more
doaj   +1 more source

Metschnikowia pulcherrima Influences the Expression of Genes Involved in PDH Bypass and Glyceropyruvic Fermentation in Saccharomyces cerevisiae

open access: yesFrontiers in Microbiology, 2017
Previous studies reported that the use of Metschnikowia pulcherrima in sequential culture fermentation with Saccharomyces cerevisiae mainly induced a reduction of volatile acidity in wine. The impact of the presence of this yeast on the metabolic pathway
Mohand Sadoudi   +4 more
doaj   +1 more source

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