Results 121 to 130 of about 21,936 (247)

Post-translational modifications of pyruvate dehydrogenase complex in cardiovascular disease

iScience
Summary: Pyruvate dehydrogenase complex (PDC) is a crucial enzyme that connects glycolysis and the tricarboxylic acid (TCA) cycle pathway. It plays an essential role in regulating glucose metabolism for energy production by catalyzing the oxidative ...
Bo Guo, Fujiao Zhang, Yue Yin, Xingmin Ning, Zihui Zhang, Qinglei Meng, Ziqi Yang, Wenhua Jiang, Manling Liu, Yishi Wang, Lijuan Sun, Lu Yu, Nan Mu   +12 more
doaj  

Pyruvate decarboxylating action of L-cycloserine. The significance of this in understanding its metabolic inhibitory action.

Journal of Biological Chemistry, 1986
We present evidence which demonstrates that L-cycloserine, structural analog of L-alanine, which is known to be an effective aminotransferase inhibitor, is also a potent inhibitor of cellular pyruvate metabolism. This effect was found to be related to its almost instantaneous action in decreasing pyruvate concentrations in a dose-dependent manner.
Pérez-Sala, Dolores, Cerdán, Sebastián, Ballesteros, Paloma, Sánchez Ayuso, Matilde, Parrilla, Roberto L.   +4 more
openaire   +4 more sources

Experimental ‏review ‏of ‏cobalt ‏induced cardiomyopathy

Russian Open Medical Journal, 2017
The heart is a target of injury for many chemical compounds, both medically prescribed and not. Pathophysiological mechanisms underlying development of chemical-induced cardiomyopathies vary depending on the inciting agent, and can include: direct toxic ...
Igor ‏V. Zadnipryany, Olga ‏S. Tretiakova, Tatiana P. Sataieva, Walery ‏Zukow   +3 more
doaj   +1 more source

Role of the malic enzyme in metabolism of the halotolerant methanotroph Methylotuvimicrobium alcaliphilum 20Z.

PLoS ONE, 2019
The bacteria utilizing methane as a growth substrate (methanotrophs) are important constituents of the biosphere. Methanotrophs mitigate the emission of anthropogenic and natural greenhouse gas methane to the environment and are the promising agents for ...
Olga N Rozova, Ildar I Mustakhimov, Sergei Y But, Aleksandr S Reshetnikov, Valentina N Khmelenina   +4 more
doaj   +1 more source

Effect of colimycin on the decarboxylation of pyruvate from serine inEscherichia coli andCitrobacter intermedius [PDF]

, 1977
Jocelyne Cornu-Favet, Elisabeth Schorer
openalex   +1 more source

A Thiamin-bound, Pre-decarboxylation Reaction Intermediate Analogue in the Pyruvate Dehydrogenase E1 Subunit Induces Large Scale Disorder-to-Order Transformations in the Enzyme and Reveals Novel Structural Features in the Covalently Bound Adduct [PDF]

, 2006
Palaniappa Arjunan, Martin Sax, Andrew P. J. Brunskill, Krishnamoorthy Chandrasekhar, Natalia S. Nemeria, Sheng Zhang, Frank Jordan, William Furey   +7 more
openalex   +1 more source

Effects of type of substrate and dilution rate on fermentation in serial rumen mixed cultures

Frontiers in Microbiology
Forages and concentrates have consistently distinct patterns of fermentation in the rumen, with forages producing more methane (CH4) per unit of digested organic matter (OM) and higher acetate to propionate ratio than concentrates.
Emilio M. Ungerfeld, Nathaly Cancino-Padilla, Nelson Vera-Aguilera, M. Carolina Scorcione, Marcelo Saldivia, Lorena Lagos-Pailla, Lorena Lagos-Pailla, Lorena Lagos-Pailla, Milena Vera, Cristián Cerda, Camila Muñoz, Natalie Urrutia, Emilio D. Martínez   +12 more
doaj   +1 more source

Experiments on the carboxylase of pea roots [PDF]

, 1941
It is known that vitamin B1 is a growth factor for numerous bacteria and fungi including the yeasts (see the summary in Koser and Saunders (1938)). It has also been demonstrated that vitamin B1 is essential for the growth of the isolated roots of higher ...
Heegaard, Erik, Horowitz, N. H.
core  

Identification and Abiotic Stress Expression Profiling of Malic Enzyme-Associated Genes in Maize (Zea mays L.)

Plants
Malic enzyme (ME), a key enzyme involved in various metabolic pathways, catalyzes the oxidative decarboxylation of malate to generate pyruvate, CO2, and NADPH. This enzyme plays essential roles in plant growth, development, and stress responses.
Haishan Yan, Yongsheng Li, Zengke Ma, Ruihong Wang, Yuqian Zhou, Wenqi Zhou, Haijun He, Xiaojuan Wang, Xiaorong Lian, Xiaoyun Dong, Lirong Yao   +10 more
doaj   +1 more source

Carbon isotope effects on the decarboxylation of carboxylic acids. Comparison of the lactate oxidase reaction and the degradation of pyruvate by H2O2 [PDF]

, 1988
E. W. Melzer, Hanns‐Ludwig Schmidt
openalex   +1 more source