Results 121 to 130 of about 111,556 (245)

Engineering of the Thiamine Diphosphate‐Dependent JanthE for the Synthesis of Tertiary Alcohols

open access: yesChemistry – A European Journal, Volume 31, Issue 35, June 23, 2025.
The synthesis of chiral tertiary alcohols is in high demand. Here we investigate in detail the aldehyde–ketone cross‐coupling reactions catalyzed by the promising thiamine diphosphate‐dependent lyase JanthE. Focusing on both reaction parameters and engineering, we rationally develop JanthE to improve its applicability and demonstrate its evolvability ...
Lucrezia Lanza   +7 more
wiley   +1 more source

Coordinate cis-[Cr(C2O4)(pm)(OH2)2]+ Cation as Molecular Biosensor of Pyruvate’s Protective Activity Against Hydrogen Peroxide Mediated Cytotoxity

open access: yesSensors, 2008
In this paper instrumental methods of carbon dioxide (CO2) detection in biological material were compared. Using cis-[Cr(C2O4)(pm)(OH2)2]+ cation as a specific molecular biosensor and the stopped-flow technique the concentrations of CO2 released from the
Lech Chmurzyński   +5 more
doaj  

Evolutionary analysis of the TPP-dependent enzyme family [PDF]

open access: yes, 2008
The evolutionary relationships of the thiamine pyrophosphate (TPP)-dependent family of enzymes was investigated by generation of a neighbor joining phylogenetic tree using sequences from the conserved pyrophosphate (PP) and pyrimidine (Pyr) binding ...
Costelloe, S.J., Dalby, P.A., Ward, J.M.
core  

PDC1, a pyruvate/&agr;‐ketoacid decarboxylase, is involved in acetaldehyde, propanal and pentanal biosynthesis in melon (Cucumis melo L.) fruit

open access: yesThe Plant Journal, 2019
Plant pyruvate decarboxylases (PDC) catalyze the decarboxylation of pyruvate to form acetaldehyde and CO2 and are well known to play a key role in energy supply via fermentative metabolism in oxygen-limiting conditions.
Minmin Wang   +5 more
semanticscholar   +1 more source

Purification, characterisation and cDNA sequencing of pyruvate decarboxylase from Zygosaccharomyces bisporus [PDF]

open access: yes, 2000
Cells of the wild-type yeast strain Zygosaccharomyces bisporus CBS 702 form alpha-hydroxy ketones from aromatic amino acid precursors during fermentation, Pyruvate decarboxylase (PDC, E.C. 4.1.1.1), the key enzyme of this biotransformation catalysing the
Berger, Ralf Günter   +3 more
core   +2 more sources

Gold(I)-catalysed synthesis of a furan analogue of thiamine pyrophosphate. [PDF]

open access: yes, 2014
An analogue of thiamine having a furan ring in place of the thiazolium ring has been synthesised by a short and efficient route, involving gold(I)-catalysed cyclisation of an alkynyl alcohol to form the furan ring.
Iqbal, Amjid   +2 more
core   +3 more sources

Post-translational modifications of pyruvate dehydrogenase complex in cardiovascular disease

open access: yesiScience
Summary: Pyruvate dehydrogenase complex (PDC) is a crucial enzyme that connects glycolysis and the tricarboxylic acid (TCA) cycle pathway. It plays an essential role in regulating glucose metabolism for energy production by catalyzing the oxidative ...
Bo Guo   +12 more
doaj  

Role of the malic enzyme in metabolism of the halotolerant methanotroph Methylotuvimicrobium alcaliphilum 20Z.

open access: yesPLoS ONE, 2019
The bacteria utilizing methane as a growth substrate (methanotrophs) are important constituents of the biosphere. Methanotrophs mitigate the emission of anthropogenic and natural greenhouse gas methane to the environment and are the promising agents for ...
Olga N Rozova   +4 more
doaj   +1 more source

Experiments on the carboxylase of pea roots [PDF]

open access: yes, 1941
It is known that vitamin B1 is a growth factor for numerous bacteria and fungi including the yeasts (see the summary in Koser and Saunders (1938)). It has also been demonstrated that vitamin B1 is essential for the growth of the isolated roots of higher ...
Heegaard, Erik, Horowitz, N. H.
core  

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