Disrupted metabolic flux balance between pyruvate dehydrogenase and pyruvate carboxylase in human fatty liver. [PDF]
MetabolismPark JM +8 more
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Directed Evolution of Branched-Chain α-Keto Acid Decarboxylase for 3-Hydroxypropionic Acid Production in <i>Escherichia coli</i> via Oxaloacetate. [PDF]
ACS Synth BiolWang C, Olsthoorn RCL, de Groot HJM.
europepmc +1 more source
The influence of TC0668 on glycometabolism modulation in <i>Chlamydia muridarum</i>-infected host cells. [PDF]
Microbiol SpectrYu N +5 more
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Noradrenaline effects on pyruvate decarboxylation: Correlation with calcium signaling
Journal of Neuroscience Research, 1999 Noradrenaline effects on the rate of metabolism of pyruvate to acetyl coenzyme A, catalyzed by the pyruvate dehydrogenase complex, was measured in primary cultures of mouse astrocytes as rate of production of labeled CO(2) from 1-[(14) C]pyruvate in the absence of competing glucose in the medium.
Ye Chen‐Izu, Leif Hertz
semanticscholar +4 more sources
Pyruvate decarboxylation and its relationship to contraction of cardiac myofibrils
American Journal of Physiology-Legacy Content, 1966 H Diaz de Arce, Lamar Crevasse, JC Shipp
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Pyruvate Decarboxylase: A Molecular Modeling Study of Pyruvate Decarboxylation and Acyloin Formation
Journal of the American Chemical Society, 1996 Using crystal structure data for the pyruvate decarboxylase from Saccharomyces uvarum (which is nearly identical with the enzyme from Saccharomyces cerevisiae), molecular modeling studies have been carried out to investigate the mode of action of the enzyme. Each step of the decarboxylation mechanism can be explained by assuming that the 4‘-amino group
Mario Lobell, David H. G. Crout
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Thiamin deficiency effects on rat leukocyte pyruvate decarboxylation rates
The American Journal of Clinical Nutrition, 1978 Thiamin status usually is assessed by urinary excretion of thiamin or by exogenous thiamin pyrophosphate (TPP) stimulation of erythrocyte transketolase activity. Because of the possible great utility of a biologically and chemically sensitive alternative method for thiamin status assessment, studies were made of rat leukocyte pyruvate decarboxylation ...
JN Hathcock
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International Journal of Biochemistry, 1991 1. D-Glucose (0.5-16.7 mM) preferentially stimulates aerobic glycolysis and D-[3,4-14C]glucose oxidation, relative to D-[5-3H]glucose utilization in rat pancreatic islets, the concentration dependency of such a preferential effect displaying a sigmoidal pattern. 2.
Willy J. Malaisse +3 more
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Impaired oxidative decarboxylation of pyruvate in fibroblasts from patients with Parkinson's disease
Journal of Neural Transmission - Parkinson's Disease and Dementia Section, 1994 Whether or not a reported deficiency in brain mitochondrial complex I activity in Parkinson's disease represents a defect encompassing other organs or tissues has been a source of some controversy. We have examined mitochondrial respiration in fibroblasts from patients with Parkinson's disease by measuring the oxidative decarboxylation of [2-14C ...
Catherine Mytilineou +5 more
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Carbon-13 and deuterium isotope effects on oxalacetate decarboxylation by pyruvate carboxylase
Biochemistry, 1986 Deuterium and 13C isotope effects for the enzymic decarboxylation of oxalacetate showed that both deuterium- and 13C-sensitive steps in the reaction are partially rate limiting. A normal alpha-secondary effect of 1.2 per deuterium was calculated for the reaction in which pyruvate-d3 was the substrate, suggesting that the enolate of pyruvate was an ...
Paul V. Attwood +2 more
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