Free Energy of Activation for the Comorosan Effect [PDF]
arXiv, 2007 Initial reaction rate data for lactic dehydrogenase / pyruvate, lactic dehydrogenase / lactate and malic dehydrogenase / malate enzyme reactions were analyzed to obtain activation free energy changes of -329, -195 and -221 cal/mole, respectively, for rate increases associated with time-specific irradiation of the crystalline substrates prior to ...
arxiv
iMetaOmics, EarlyView.This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu +8 more
wiley +1 more source
Dependence of Substrate Irradiation Reaction Rate Stimulation on Lactic Dehydrogenase Source [PDF]
arXiv, 2013 Stimulation of LDH initial reaction rates by timed pre-irradiation of crystalline sodium pyruvate and lithium lactate is reported for enzymes isolated from rabbit muscle, pig heart, human erythrocytes and chicken heart. The phenomenon investigated is referred to as the Comorosan effect.
arxiv
Mitochondrial dysfunction: Related diseases, influencing factors, and detection
Interdisciplinary Medicine, EarlyView.Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li +9 more
wiley +1 more source
Molecular mechanism of ethylene stimulation of latex yield in rubber tree (Hevea brasiliensis) revealed by de novo sequencing and transcriptome analysis [PDF]
, 2016 Differential expression of unigenes involved in hormone signaling in E8 and E24 compared to C samples of Hevea brasiliensis. Ethylene signalling pathway: ETR1: ETHYLENE RESPONSE 1; CTR1: CONSTITUTIVE TRIPLE RESPONSE 1; EIN2: ETHYLENE INSENSITIVE 2; EIN3:
Jin-Ping Liu +3 more
core +9 more sources
Quantitative model for $^{13}$C tracing applied to citrate production and secretion of prostate epithelial tissue [PDF]
arXiv, 2019 Healthy human prostate epithelial cells have the unique ability to produce and secrete large amounts of citrate into the lumen of the prostate. Citrate is a Krebs cycle metabolite produced in the condensation reaction between acetyl-CoA and oxaloacetate in the mitochondria of the cell. With the application of $^{13}$C enriched substrates, such as $^{13}
arxiv
PROTEOMICS, EarlyView.ABSTRACT Isolated complex I deficiency (ICD) is commonly associated with mitochondrial diseases and closely mimics subacute necrotising encephalomyelopathy. This disorder is characterised by metabolic perturbations that affect energy metabolism pathways, including fatty acid metabolism.
Sibonelo Glen Khumalo +2 more
wiley +1 more source
Separation of protein X from the dihydrolipoyl transacetylase component of the mammalian pyruvate dehydrogenase complex and the study of protein X [PDF]
, 1989 Call number: LD2668 .T4 BICH 1989 P69Master of ScienceBiochemistry and Molecular Biophysics Interdepartmental ...
Powers-Greenwood, Susan L.
core
Comparative Proteomics of Salinity Stress Responses in Fish and Aquatic Invertebrates
PROTEOMICS, EarlyView.ABSTRACT Fluctuating salinity is symptomatic of climate change challenging aquatic species. The melting of polar ice, rising sea levels, coastal surface and groundwater salinization, and increased evaporation in arid habitats alter salinity worldwide. Moreover, the frequency and intensity of extreme weather events such as rainstorms and floods increase,
Maxime Leprêtre +3 more
wiley +1 more source
Metabolism of lactose by Clostridium thermolacticum growing in continuous culture [PDF]
, 2018 The objective of the present study was to characterize the metabolism of Clostridium thermolacticum, a thermophilic anaerobic bacterium, growing continuously on lactose (10gl−1) and to determine the enzymes involved in the pathways leading to the ...
Collet, Christophe +4 more
core