Results 231 to 240 of about 156,917 (287)
The FEBS Journal, EarlyView.Alpha‐crystallin B chain (CRYAB) has been reported to stabilize mothers against decapentaplegic homolog 4 (SMAD4) in transforming growth factor‐β (TGF‐β) signaling, enabling target gene transcription. We show nuclear CRYAB–SMAD4 interaction for the first time in human skeletal muscle fibers and its regulation by exercise.
Kirill Schaaf +7 more
wiley +1 more source
Prebiotic aqueous reactions catalyzed by native nickel without hydrogen
The FEBS Journal, EarlyView.Serpentinizing (H2‐producing) hydrothermal vents are candidate environments for metabolic origin. They generate highly reducing conditions that convert CO2 to formate and methane in abiotic reactions resembling reactions of the acetyl‐CoA pathway of CO2 fixation. They also contain natural catalysts. Native nickel (Ni0), like Fe0, Co0, and their alloys,
Carolina Garcia Garcia +2 more
wiley +1 more source
Fisheries Oceanography, EarlyView.ABSTRACT Yellowfin sole (Limanda aspera) support the largest flatfish fishery in the world and contribute substantially to the eastern Bering Sea (EBS) flatfish catch. The EBS has been warming and acidifying, trends that are expected to intensify into the future.
Emily Slesinger +5 more
wiley +1 more source
Lactobacillus plantarum: From Application to Protein Expression (Lactobacillus plantarum: Sovellutuksista proteiinien ilmentymiseen) [PDF]
Plumed-Ferrer, Carme
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Pyruvate Dehydrogenase Complex Deficiency
2016Pyruvate dehydrogenase complex (PDHc) deficiency usually first manifests at a young age and is rarely diagnosed in adulthood. The clinical picture varies from neonatal death with overwhelming lactic acidosis to a relatively benign course early in life.
Mirian C. H. Janssen, Shamima Rahman
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Complexities of the pyruvate dehydrogenase complex
Neurology, 1998If one were to throw a dart at the center of a biochemical chart for intermediary metabolism, it would land on acetyl-CoA. This metabolite is at the convergence of pyruvate, fatty acid, and ketone body metabolism. Condensation of acetyl-CoA with oxaloacetate forms citric acid, the entry point into the tricarboxylic acid cycle.
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Disorders of the pyruvate dehydrogenase complex
Journal of Inherited Metabolic Disease, 1986AbstractPyruvate dehydrogenase deficiency may be a non‐specific consequence of many different neurological degenerative disorders. There are also serious methodological problems in estimating the activity of this enzyme complex.
D, Stansbie, S J, Wallace, C, Marsac
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Regulation of the pyruvate dehydrogenase complex
Biochemical Society Transactions, 2006The PDC (pyruvate dehydrogenase complex) plays a central role in the maintenance of glucose homoeostasis in mammals. The carbon flux through the PDC is meticulously controlled by elaborate mechanisms involving post-translational (short-term) phosphorylation/dephosphorylation and transcriptional (long-term) controls.
M S, Patel, L G, Korotchkina
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The pyruvate dehydrogenase complex during aging
Mechanisms of Ageing and Development, 1984Acetylcholine synthesis and pyruvate oxidation decline with age. To determine the role of the pyruvate dehydrogenase complex in these age-related deficits, its activity and activation state were measured in vivo and in vitro in the brains of 3-, 10- and 30-month-old mice.
H, Ksiezak-Reding +2 more
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