Results 171 to 180 of about 68,490 (304)

Pyruvate Dehydrogenase Kinase Protects Dopaminergic Neurons from Oxidative Stress in Drosophila DJ-1 Null Mutants. [PDF]

Mol Cells, 2022
Lee Y, Kim J, Kim H, Han JE, Kim S, Kang KH, Kim D, Kim JM, Koh H.   +8 more
europepmc   +1 more source

TIME COURSE OF A 40 HOUR FAST ON PYRUVATE DEHYDROGENASE ACTIVATION AND KINASE EXPRESSION IN HUMAN SKELETAL MUSCLE

, 2001
L. L. Spriet, Rebecca J. Tunstall, Matthew J. Watt, Mark Hargreaves, David Cameron‐Smith   +4 more
openalex   +1 more source

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source

Renometabolic disorder in experimental rat model of polycystic ovarian syndrome is reversed by acetate-mediated inhibition of pyruvate dehydrogenase kinase 4. [PDF]

BMC Nephrol
Areloegbe SE, Atuma CL, Aturamu A, Ajadi IO, Adelekan OE, Ajadi MB, Akintayo CO, Omoruyi GO, Onyekweli SO, Anifowose OF, Amusa OA, Ajayi K, Oyewole PA, Adegoke TE, Olaniyi KS.   +14 more
europepmc   +1 more source

Corrigendum to "Deficiency of pyruvate dehydrogenase kinase 4 sensitizes mouse liver to diethylnitrosamine and arsenic toxicity through inducing apoptosis" [Liver Res. 2 (2018) 100-107]. [PDF]

Liver Res, 2023
Choiniere J, Lin MJ, Wang L, Wu J.
europepmc   +1 more source

Regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) gene expression by glucocorticoids and insulin [PDF]

, 2009
Sara Connaughton, Farhana Chowdhury, Ramy R. Attia, Shulan Song, Yi Zhang, Marshall B. Elam, George A. Cook, Edwards A. Park   +7 more
openalex   +1 more source

Lactate and Lactylation in AKI‐to‐CKD: Epigenetic Regulation and Therapeutic Opportunities

Cell Proliferation, EarlyView.
ABSTRACT Lactate is not only a byproduct of glycolysis, but is also considered an energy source, gluconeogenic precursor, signalling molecule and protein modifier during the process of cellular metabolism. The discovery of lactylation reveals the multifaceted functions of lactate in cellular metabolism and opens new avenues for lactate‐related research.
Yi Hou, Dongwei Liu, Zuishuang Guo, Cien Wei, Fengyu Cao, Yue Xu, Qi Feng, Fengxun Liu   +7 more
wiley   +1 more source

Increased oxidative phosphorylation through pyruvate dehydrogenase kinase 2 deficiency ameliorates cartilage degradation in mice with surgically induced osteoarthritis. [PDF]

Exp Mol Med
Han J, Kim YH, Han S.
europepmc   +1 more source

Inhibition of pyruvate dehydrogenase kinase improves carbohydrate utilization in Nile tilapia by regulating PDK2/4-PDHE1α axis and insulin sensitivity. [PDF]

Anim Nutr, 2022
Luo Y, Zhou W, Li R, Limbu SM, Qiao F, Chen L, Zhang M, Du ZY.   +7 more
europepmc   +1 more source

Regulation of Pyruvate Dehydrogenase Kinase 4 (PDK4) by Thyroid Hormone [PDF]

, 2009
Ramy R. Attia, Sara Connnaughton, Lindsey R. Boone, Fang Wang, Marshall B. Elam, Gene C. Ness, George A. Cook, Edwards A. Park   +7 more
openalex   +1 more source