Results 131 to 140 of about 94,058 (273)

Diatom triacylglycerol metabolism: from carbon fixation to lipid droplet degradation

Biological Reviews, EarlyView.
ABSTRACT Diatoms are a prominent microalgae family that has attracted interest for its production of molecules of biotechnological interest. Their fatty acid profile is rich in health‐beneficial omega‐3 eicosapentaenoic acid (EPA). Furthermore, under nutrient‐deprived conditions, many diatom species, notably Phaeodactylum tricornutum, Thalassiosira ...
Victor Murison, Josiane Hérault, Justine Marchand, Lionel Ulmann   +3 more
wiley   +1 more source

Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers

Cell Reports, 2019
Summary: Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a tumor suppressor and bi-functional lipid and protein phosphatase. We report that the metabolic regulator pyruvate dehydrogenase kinase1 (PDHK1) is a synthetic-essential gene in ...
Nilanjana Chatterjee, Evangelos Pazarentzos, Manasi K. Mayekar, Philippe Gui, David V. Allegakoen, Gorjan Hrustanovic, Victor Olivas, Luping Lin, Erik Verschueren, Jeffrey R. Johnson, Matan Hofree, Jenny J. Yan, Billy W. Newton, John V. Dollen, Charles H. Earnshaw, Jennifer Flanagan, Elton Chan, Saurabh Asthana, Trey Ideker, Wei Wu, Junji Suzuki, Benjamin A. Barad, Yuriy Kirichok, James S. Fraser, William A. Weiss, Nevan J. Krogan, Asmin Tulpule, Amit J. Sabnis, Trever G. Bivona   +28 more
doaj  

Phosphoenolpyruvate Carboxykinase Is Involved in the Decarboxylation of Aspartate in the Bundle Sheath of Maize [PDF]

, 1999
We recently showed that maize (Zea mays L.) leaves contain appreciable amounts of phosphoenolpyruvate carboxykinase (PEPCK; R.P. Walker, R.M. Acheson, L.I. Técsi, R.C. Leegood [1997] Aust J Plant Physiol 24: 459–468).
Chen, Z., Leegood, R.C., Walker, R.P., Wingler, A.   +3 more
core   +2 more sources

Testis‐Specific PDHA2 Is Required for Proper Meiotic Recombination and Chromosome Organisation During Spermatogenesis

Cell Proliferation, EarlyView.
PDHA2, a testis‐specific subunit of pyruvate dehydrogenase, is required for the conversion of pyruvate to acetyl‐CoA. Its absence results in decreased acetyl‐CoA and precursors for metabolites and energy during spermatogenesis. This results in decreased histone acetylation, defective chromosome structure and moderately reduced crossovers, ultimately ...
Guoqiang Wang, Kailun Fang, Yongliang Shang, Xu Zhou, Qiqi Shao, Si Li, Ping Wang, Charlie Degui Chen, Liangran Zhang, Shunxin Wang   +9 more
wiley   +1 more source

Expression Regulation of Gluconeogenesis Related Genes in Ovine Skeletal Muscle Cells

Frontiers in Bioscience-Landmark
Background: Under fasting conditions, the pathway converting gluconeogenesis precursors into muscle glycogen becomes crucial due to reduced glycogen reserves. However, there is limited research on skeletal muscle gluconeogenesis and the impact of fasting
Yue Pang, Sile Hu, Binhong Wen, Dubala Wu, Feng Song, Jun Yin, Jianghong Wu   +6 more
doaj   +1 more source

Effect of Copper on the Humoral and Biochemical Indices of the Teleost fish, Anabas testudineus (Bloch, 1792)

Walailak Journal of Science and Technology, 2013
The effects of sub-lethal concentrations of copper and the ameliorating capacity of vitamin C on the humoral and biochemical parameters in the teleost fish, Anabas testudineus, were investigated. The 96 h LC 50 value of copper for A.
Bhaskaran Nair Girish KUMAR, Sivasankaran Bijoy NANDAN   +1 more
doaj   +1 more source

Glycolytic pyruvate kinase moonlighting activities in DNA replication initiation and elongation [PDF]

arXiv, 2020
Cells have evolved a metabolic control of DNA replication to respond to a wide range of nutritional conditions. Accumulating data suggest that this poorly understood control depends, at least in part, on Central Carbon Metabolism (CCM). In Bacillus subtilis , the glycolytic pyruvate kinase (PykA) is intricately linked to replication.
arxiv  

Effect of phenylephrine on pyruvate dehydrogenase activity in rat hepatocytes and its interaction with insulin and glucagon [PDF]

, 1983
In isolated rat hepatocytes phenylephrine promotes a rapid increase in the amount of pyruvate dehydrogenase present in its active form (PDHa). This action is mediated by α1-adrenergic receptors and is not observed in Ca2+-depleted hepatocytes.
Assimacopoulos-Jeannet, F., Jeanrenaud, B., McCormack, J.G.   +2 more
core   +1 more source

Glycaemic sugar metabolism and the gut microbiota: past, present and future

The FEBS Journal, Volume 292, Issue 6, Page 1421-1436, March 2025.
Increased sugar consumption is a main driver of the increased prevalence of obesity and non‐communicable diseases (NCDs). Therefore, understanding host and microbial sugar metabolism and its metabolic effects is crucial. A high‐sugar diet can induce gut dysbiosis, and gut microbial sugar fermentation can produce deleterious metabolites, potentially ...
Florine H. M. Westerbeke, Ilias Attaye, Melany Rios‐Morales, Max Nieuwdorp   +3 more
wiley   +1 more source

Hepatoprotective efficacy of Hypnea muciformis ethanolic extract on CCl4 induced toxicity in rats

Brazilian Archives of Biology and Technology, 2012
The ethanolic extract of Hypnea muciformis (red algae) was tested for hepatoprotective activity against experimentally induced liver damage by Carbon tetrachloride (CCl4) in male albino rats.
Giridharan Bupesh, Chinnaiah Amutha, Sakthivel Vasanth, Natesan Manoharan, Ramalingam Senthil Raja, Raju Krishnamoorthy, Periyasamy Subramanian   +6 more
doaj   +1 more source