Results 171 to 180 of about 94,058 (273)

Development of a Mouse Model of Uremic Cardiomyopathy: Investigating the Impact of Chronic Kidney Disease on Cardiac Function and Signaling Pathway

The FASEB Journal, Volume 39, Issue 10, 31 May 2025.
Molecular changes in a mouse model of uremic cardiomyopathy. This model of 2,8‐DHA‐induced nephropathy in 129/Sv mice showed clinical features of uremic cardiomyopathy like reduced cardiac function and cardiac interstitial fibrosis and an unfavorable balance between protective and detrimental cardiac signaling.
Julia Moellmann, Katja Glandien, Barbara M. Klinkhammer, Julia Wollenhaupt, Heidi Noels, Joachim Jankowski, Corinna Lebherz, Peter Boor, Michael Lehrke, Nikolaus Marx   +9 more
wiley   +1 more source

Regulation of pyruvate dehydrogenase and pyruvate dehydrogenase phosphate phosphatase activity in rat epididymal fat-pads. Effects of starvation, alloxan-diabetes and high-fat diet [PDF]

, 1976
D. Stansbie, R M Denton, B J Bridges, Helen T. Pask, P J Randle   +4 more
openalex   +1 more source

PTPN2 Negatively Regulates Macrophage Immune Responses and Cellular Bioenergetics

The FASEB Journal, Volume 39, Issue 9, 15 May 2025.
It is the deletion that upregulates phosphorylation of STAT1 and STAT3, coinciding with a modulation of several genes involved in immune responses and metabolism. These lead to the Warburg effect, characterized by a decrease in mitochondrial respiration and an increase in glycolysis, in proinflammatory macrophages lacking TC‐PTP. These macrophages also
Valerie Vinette, Yevgen Zolotarov, Alexandre Poirier, Zuzet Martinez Cordova, Isabelle Aubry, Michel L. Tremblay   +5 more
wiley   +1 more source

Activation of pyruvate dehydrogenase in adipose tissue by insulin. Evidence for an effect of insulin on pyruvate dehydrogenase phosphate phosphatase [PDF]

, 1975
Chhabirani Mukherjee, Robert L. Jungas
openalex   +1 more source

Occupancy of phosphorylation sites in pyruvate dehydrogenase phosphate complex in rat heart in vivo. Relation to proportion of inactive complex and rate of re-activation by phosphatase [PDF]

, 1982
Graham J. Sale, P J Randle
openalex   +1 more source

Biogenesis of Organelles and Membrane Proteins. [PDF]

, 1988
Harmey, Matthew A., Neupert, Walter, Nicholson, Donald W., Stuart, Rosemary A.   +3 more
core   +1 more source

Calcium and magnesium ions as effectors of adipose-tissue pyruvate dehydrogenase phosphate phosphatase [PDF]

, 1974
David L. Severson, Richard M. Denton, Helen T. Pask, Philip J. Randle   +3 more
openalex   +1 more source

Dietary Effects of Probiotic Bacteria, Bacillus amyloliquefaciens AV5 on Growth, Serum and Mucus Immune Response, Metabolomics, and Lipid Metabolism in Nile Tilapia (Oreochromis niloticus)

Aquaculture Nutrition
In the present study, we investigated the effect of dietary supplementation with the probiotic Bacillus amyloliquefaciens AV5 (OR647358) on the growth, serum and mucus immune responses, metabolomics, and lipid metabolism of Oreochromis niloticus. Fishes (
Vicent Michael Shija, Glory Emanuel Zakaria, Kwaku Amoah, Li Yi, Junwei Huang, Fortunatus Masanja, Zhong Yong, Jia Cai   +7 more
doaj   +1 more source

Remodeling of Hepatic Glucose Metabolism in Response to Early Weaning in Piglets

Animals
This study aimed to investigate the dynamic changes in hepatic glucose metabolism in response to early weaning. A total of 60 piglets were randomly selected and weaned at 21 days old. Six piglets were slaughtered on the weaning day (d0) and at 1 (d1), 4 (
Chengbing Yu, Di Wang, Cheng Shen, Zhen Luo, Hongcai Zhang, Jing Zhang, Weina Xu, Jianxiong Xu   +7 more
doaj   +1 more source

Cellular distribution of pyruvate dehydrogenase phosphatase. Activity in normal, hyperinsulinized and diabetic rats [PDF]

, 1976
E.A. Siess, O. Wieland
openalex   +1 more source