Consensus Recommendations for Hyperpolarized [1-13C]pyruvate MRI Multi-center Human Studies [PDF]
Magnetic resonance imaging of hyperpolarized (HP) [1-13C]pyruvate allows in-vivo assessment of metabolism and has translated into human studies across diseases at 15 centers worldwide. Consensus on best practice for multi-center studies is required to develop clinical applications.
arxiv
Effects of Ca2+ and Mg2+ on the activity of pyruvate dehydrogenase phosphate phosphatase within toluene-permeabilized mitochondria [PDF]
Peter J. W. Midgley+3 more
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Dephosphorylation of pig heart pyruvate dehydrogenase phosphate complexes by pig heart pyruvate dehydrogenase phosphate phosphatase [PDF]
A L Kerbey, P J Randle, A. Kearns
openalex +1 more source
Indirect Zero Field NMR Spectroscopy [PDF]
This study pioneers the two-field correlation spectroscopy (COSY) in zero to ultralow field (ZULF) liquid state NMR, employing hyperpolarized [1-$^{13}$C]pyruvate as a model system. We demonstrate the successful integration of signal amplification by reversible exchange (SABRE) for hyperpolarization, enabling the detection of ZULF COSY spectra with ...
arxiv
Reciprocal Control of Pyruvate Dehydrogenase Kinase and Phosphatase by Inositol Phosphoglycans: Dynamic State Set by “Push-Pull” System [PDF]
Patricia McLean+6 more
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MEMO: A Method for Computing Metabolic Modules for Cell-Free Production Systems
Kamp von, A., Klamt, S.
core +1 more source
Phosphorylation of additional sites on pyruvate dehydrogenase inhibits its re-activation by pyruvate dehydrogenase phosphate phosphatase [PDF]
P H Sugden+3 more
openalex +1 more source
Circulating factors and insulin resistance. II. The action of the novel myo-inositol cyclic 1,2-inositol phosphate phosphoglycan insulin antagonist from human plasma in regulating pyruvate dehydrogenase phosphatase. [PDF]
Gail Galasko+4 more
openalex +1 more source
Use of toluene-permeabilized mitochondria to study the regulation of adipose tissue pyruvate dehydrogenase in situ. Further evidence that insulin acts through stimulation of pyruvate dehydrogenase phosphate phosphatase [PDF]
Andrew P. Thomas, R M Denton
openalex +1 more source
Sensitivity of pyruvate dehydrogenase phosphate phosphatase to magnesium ions. Similar effects of spermine and insulin [PDF]
Andrew P. Thomas, T A Diggle, R M Denton
openalex +1 more source