Results 21 to 30 of about 59,248 (212)

Noncompetitive, Ca2 ‐independent inhibition of pyruvate dehydrogenase phosphatase by fluphenazine [PDF]

open access: closedIUBMB Life, 1999
AbstractThe effects of two different classes of calmodulin antagonists on the catalytic activities of purified pyruvate dehydrogenase (PDH) phosphatase and PDH complex (PDC) were studied. In general, PDH phosphatase was more strongly inhibited than PDC by the calmodulin antagonists with the following potency order: fluphenazine>chlorpromazine> ...
Choong‐Il Bak   +3 more
openalex   +4 more sources

Tyr-94 phosphorylation inhibits pyruvate dehydrogenase phosphatase 1 and promotes tumor growth. [PDF]

open access: hybridJ Biol Chem, 2014
Shan C   +14 more
europepmc   +3 more sources

The Role of Pyruvate Dehydrogenase Kinase in Diabetes and Obesity [PDF]

open access: yesDiabetes & Metabolism Journal, 2014
The pyruvate dehydrogenase complex (PDC) is an emerging target for the treatment of metabolic syndrome. To maintain a steady-state concentration of adenosine triphosphate during the feed-fast cycle, cells require efficient utilization of fatty acid and ...
In-Kyu Lee
doaj   +1 more source

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