Results 101 to 110 of about 95,354 (345)
Predicting immune responses to treatments, including nanomedicines, with high throughput test is challenging due to the immunoreactome's complexity and plasticity. A predictive screening platform integrating pathway activation and gene profiling in macrophages has been developed as a versatile tool for designing effective immunotherapies.
Sonia Becharef+12 more
wiley +1 more source
A STUDY IN MAN OF CEREBRAL BLOOD FLOW AND CEREBRAL GLUCOSE, LACTATE AND PYRUVATE METABOLISM BEFORE AND AFTER EATING* [PDF]
George G. Rowe+4 more
openalex +1 more source
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang+14 more
wiley +1 more source
Indoleacetic Acid and the Utilization of Radioactive Pyruvate and Acetate by Wheat Roots. [PDF]
Irwin B. Perlis, James F. Nance
openalex +1 more source
A Kinetic Analysis of the Iodination of Pyruvic Acid and Pyruvate Esters [PDF]
In the present work the relative rates of iodination of pyruvic acid and ethyl and methyl pyruvate have been compared at 25.0° C. These studies allow the determination of the respective free energies of activation for these processes.
Hegazi, Mohamed M. Fahmi
core +1 more source
This study reveals that histone lactylation, a modification derived from lactate, plays a crucial role in ferroptosis resistance in ectopic endometrial stromal cells. This resistance is mediated via the HIF1A/HMOX1 pathway regulated by METTL3. In vivo, a combination of 2‐DG and erastin shows promise as an effective treatment for endometriosis ...
Zongwen Liang+8 more
wiley +1 more source
Studies on the Enolization of Pyruvate by Pyruvate Kinase [PDF]
openaire +2 more sources
Simulation and optimization of simultaneous fermentation and separation of butanol using pervaporation technique [PDF]
Product inhibition continues to be one of the major problems impeding the continuous production of butanol by fermentation process. Although many techniques are available which could sort out the fore mentioned problem, pervaporation continues to be the ...
Kottukappally, Aby J+1 more
core
This study identifies a novel oncogenic role and a previously unrecognized phosphorylation substrate of BCKDK in RCC, wherein it promotes tumor progression and drug resistance through AKT phosphorylation at both Thr308 and Ser473 sites and activation of AKT/mTOR and AKT/ABCB1 signaling pathways, offering a promising prognostic marker and therapeutic ...
Qin Tian+18 more
wiley +1 more source