Results 171 to 180 of about 95,354 (345)
3-Bromopyruvate Impairs Mitochondrial Function in <i>Trypanosoma cruzi</i>. [PDF]
Pathogensda Costa RO +7 more
europepmc +1 more source
Advanced Science, EarlyView.This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen +12 more
wiley +1 more source
Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy
Advanced Science, EarlyView.This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao +8 more
wiley +1 more source
Mechanisms for Orofacial Pain: Roles of Immunomodulation, Metabolic Reprogramming, Oxidative Stress and Epigenetic Regulation. [PDF]
BiomedicinesKhan S, Tao F.
europepmc +1 more source
Pyruvate Oxidation by Extracts of Tetrahymena pyriformis
, 1954 Gerald R. Seaman
openalex +1 more source
Advanced Science, EarlyView.RSPO2 and GDF9:BMP15 heterodimers—core components of oocyte‐secreted factors (OSFs)—coordinate to shape the molecular architecture of preantral granulosa cells via gene‐specific synergistic and antagonistic regulation, mediated through CTNNB1–SMAD2 signaling crosstalk.
Yingmei Wang +7 more
wiley +1 more source
THE RÔLE OF PANTOTHENIC ACID IN THE METABOLISM OF PYRUVATE BY PROTEUS MORGANII
, 1948 Olive E. McElroy, Albert Dorfman
openalex +1 more source