Results 291 to 300 of about 95,354 (345)
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Effects of pyruvate on pyruvate dehydrogenase kinase of rat heart

Molecular and Cellular Biochemistry, 1995
Sensitivity of rat heart pyruvate dehydrogenase kinase (PDHK) to pyruvate inhibition was tested under various conditions using pyruvate dehydrogenase complex (PDC) in mitochondria (mPDC) and in a high speed precipitate of whole tissue homogenates (hPDC).
Haldane G. Coore, Tonia C. Carter
openaire   +3 more sources

Diastereo- and Enantioselective Direct Henry Reaction of Pyruvates Mediated by Chiral P-Spiro Tetraaminophosphonium Salts

, 2009
The stereoselective direct Henry reaction of pyruvates mediated by chiral P-spiro tetraaminophosphonium salts is described.
D. Uraguchi   +4 more
semanticscholar   +1 more source

Adsorption states and modifier-substrate interactions on Pt(111) relevant to the enantioselective hydrogenation of alkyl pyruvates in the Orito reaction.

Journal of the American Chemical Society, 2003
Reflectance FTIR spectroscopy (RAIRS) was used to study the chemisorption and intermolecular interactions of methyl pyruvate and (+/-)-1-(1-naphthyl)ethylamine (NEA) on Pt(111).
S. Lavoie, M. Laliberté, P. McBreen
semanticscholar   +1 more source

Pyruvate Carboxylase and Pyruvate Dehydrogenase Deficiency [PDF]

open access: possible, 2014
Pyruvate carboxylase and pyruvate dehydrogenase deficiency are the most common disorders in pyruvate metabolism and almost always affect the central nervous system. The severity and the clinical phenotypes vary, with a range from overwhelming neonatal lactic acidosis and early death to milder presentations.
openaire   +1 more source

Pyruvate inhibition of pyruvate dehydrogenase kinase is a physiological variable

Biochemical and Biophysical Research Communications, 1985
Pyruvate inhibited pyruvate dehydrogenase kinase activity in mitochondria from adipose tissue, heart, brain and kidney of fed rats. Starvation for 24 h led to increased kinase activity in mitochondria from adipose tissue and heart but not from brain or kidney and to reduction of pyruvate inhibition of the enzyme from adipose tissue, heart and brain ...
Deborah Lyn, Haldane G. Coore
openaire   +3 more sources

Enantioselective Mukaiyama-Aldol Reaction of Pyruvates and 1-Phenyl- 1-trimethylsilyloxyethene Catalyzed by Lanthanide/Pybox Complexes

, 2006
The enantioselective Mukaiyama-aldol reaction between 1-phenyl-1-trimethylsilyloxyethene (1) and three pyruvates (2a–c) is catalyzed by the lanthanide triflate complexes of(4S,5S)-2,6-bis[5-phenyl-4-(triisopropylsilyloxy)methyl-1,3-oxazolin-2-yl]pyridine
G. Desimoni   +3 more
semanticscholar   +1 more source

Direct catalytic asymmetric aldol reactions of pyruvates: scope and mechanism.

Organic and biomolecular chemistry, 2004
The direct aldol reaction of 2-ketoesters catalyzed by chiral bisoxazoline copper(II) complexes has been investigated. First the direct homo-aldol reaction of ethyl pyruvate is reported which proceeds to give diethyl 2-hydroxy-2-methyl-4-oxoglutarate ...
N. Gathergood   +4 more
semanticscholar   +1 more source

Regulation of pyruvate carboxylase activity by pyruvate in mice liver

International Journal of Biochemistry, 1979
Abstract 1. 1. In order to study in vivo the possible regulatory role of pyruvate concentrations on pyruvate carboxylase activity. fed or 24 hr-fasted mice received various overloads of unlabeled pyruvate. 2. 2. The effect of these overloads on the incorporation of [2- 14 C]pyruvate into blood glucose was studied. 3. 3.
P. Favarger, Simonne Rous, Sylvette Bas
openaire   +3 more sources

Synthesis and biological evaluation of substituted pyrrolidines and pyrroles as potential anticancer agents

Archiv der Pharmazie, 2020
A series of polysubstituted pyrrolidines obtained via ruthenium‐catalyzed cascade cyclization of diazo pyruvates and anilines as well as their corresponding pyrrole analogs obtained via dehydration were evaluated for their antiproliferation activities ...
Jiali Ji   +7 more
semanticscholar   +1 more source

Ethyl pyruvate

Current Opinion in Anaesthesiology, 2008
Ethyl pyruvate is a simple derivative of the endogenous metabolite, pyruvic acid. Ethyl pyruvate was shown to ameliorate some of the structural and functional changes associated with mesenteric ischemia and reperfusion in rats.Treatment with ethyl pyruvate has been shown to improve survival and ameliorate organ dysfunction in a wide variety of ...
openaire   +2 more sources

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