Results 301 to 310 of about 95,354 (345)
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Diastereodivergent control in the reactions of allylic and allenic organometallic reagents with pyruvates

, 1986
Obtention de stereoisomeres threo ou erythro suivant que l'on utilise des organometalliques allyliques ou alleniques ...
Yoshinori Yamamoto   +3 more
semanticscholar   +1 more source

Anionic rearrangement in the gas phase. The collision-induced loss of carbon monoxide from deprotonated pyruvates and hydroxyacetates

, 1990
Deprotonated pyruvates and hydroxyacetates, upon collisional activation, undergo loss of CO by anionic rearrangement through alkoxycarbonyl ion complexes, e.g.
P. Eichinger, R. Hayes, J. Bowie
semanticscholar   +1 more source

Mutations in pyruvate kinase

Human Mutation, 1996
Pyruvate kinase (PK) deficiency due to mutations of the PKLR gene is a common cause of hereditary nonspherocytic hemolytic anemia. Thus far, 55 different mutations have been described in patients with PK-deficient hemolytic anemia. Polymorphisms within the PKLR gene and in the tightly linked glucocerebrosidase (GBA) gene suggest that PK deficiency may ...
Ernest Beutler, Luciano Baronciani
openaire   +3 more sources

Diastereoselective reactions of pyruvates with but-2-enyl organometallic compounds. Stereocontrol at the tertiary carbon centre

, 1983
The reaction of pyruvates (3) with but-2-enyl-9-borabicyclo[3.3.1]nonane(2a) or its α-silyl and α-stannyl substituted derivatives (10) produced the threo-isomer [(4) or (11), respectively] stereoselectively; the latter reaction was applied to the ...
Yoshinori Yamamoto   +2 more
semanticscholar   +1 more source

Assays of Pyruvate Dehydrogenase Complex and Pyruvate Carboxylase Activity

2011
Pyruvate dehydrogenase complex (PDC) and pyruvate carboxylase (PC) are mitochondrial enzymes that provide the initial steps of the two main alternatives for pyruvate metabolism: oxidative decarboxylation vs. anaplerotic carboxylation, gluconeogenesis, and glycerogenesis.
Ghunwa Nakouzi   +2 more
openaire   +3 more sources

Asymmetric Friedel-Crafts Alkylation of Indoles with Trifluoromethyl Pyruvate Catalyzed by a Dinuclear Zinc Catalyst.

Journal of Organic Chemistry, 2018
A bimetallic cooperative catalysis model has been reported for the asymmetric Friedel-Crafts (F-C) alkylation of indoles with trifluoromethyl pyruvates using Trost's intramolecular dinuclear zinc complex as the catalyst.
Yuan-Zhao Hua   +3 more
semanticscholar   +1 more source

The mechanism of photoinduced fragmentation of alkyl pyruvates

, 1982
The finding that t-butyl pyruvate is photostable and has a much longer triplet lifetime than methyl, ethyl, isopropyl, 2-deuterioisopropyl, and benzyl pyruvates, together with triplet quenching studies, shows that alkyl pyruvates fragment from the ...
R. Davidson, D. Goodwin
semanticscholar   +1 more source

The role of electron transfer processes in the photoinduced decarboxylation of alkyl pyruvates

, 1984
Irradiation of degassed solutions of alkyl pyruvates leads to the production of carbon dioxide, the yield of which is enhanced by the presence of electron acceptors, and in the case of methylviologen, the formation of reduced methylviologen is observed ...
R. Davidson, D. Goodwin, J. Pratt
semanticscholar   +1 more source

Pyruvate kinase deficiency

Clinical Biochemistry, 1990
Pyruvate kinase (PK) deficiency was initially described by Valentine et al. in 1961. Since then, more than 300 cases have been described, including 65 in Japan. PK deficiency is the most common hereditary nonspherocytic hemolytic anemia among several red cell enzyme defects of the Embden-Meyerhof glycolytic pathway.
Hisaichi Fujii, Shiro Miwa
openaire   +3 more sources

Copper(I)-mediated and microwave-assisted C(aryl)-O(carboxylic) coupling: synthesis of benzopyranones and isolamellarin alkaloids.

Journal of Organic Chemistry, 2007
A simple and highly effective C-O(carboxylic) coupling reaction catalyzed by copper(I) salts has been developed to synthesize benzopyranones. The reaction of various 2-halobiarylcarboxylic acids was examined using microwave irradiation.
N. Thasana   +5 more
semanticscholar   +1 more source

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