Results 71 to 80 of about 95,354 (345)

Probing Early Particle‐Cell Membrane Interactions via Single‐Cell and Single‐Particle Interaction Analysis

Advanced Functional Materials, EarlyView.
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar, Christos Tapeinos, Oğulcan Işıtman, Carmine D'Amico, Alexandra Correia, Hélder A. Santos, Quan Zhou   +6 more
wiley   +1 more source

Complications neurologiques de la carence en thiamine (Vitamine B1) : A propos d’un cas avec revue de la litterature [PDF]

, 2021
Introduction: La carence en thiamine peut se manifester par deux formes cliniques : une forme cardiaque nommée béribéri humide, et une forme neurologique qui est le béribéri sec ; cette dernière peut se traduire cliniquement par une neuropathie ...
Doghmi , Kamal, El Haddad, Mariyam, El Maaroufi, Hicham, Jennane, Selim, Loubnan , Sarah, Mahtat, El Mehdi, Mikdame, Mohamed   +6 more
core   +1 more source

Enhanced Sonodynamic Bacterial Elimination and Wound Healing Therapy Based on Lanthanide Ion Doped Bi2WO6 Nanosheets and Hydrogel Platform

Advanced Functional Materials, EarlyView.
Lanthanide ytterbium ions are introduced into Bi2WO6 nanosheets to boost ROS generation under US stimulation. These ytterbium‐doped Bi2WO6 nanosheets serve as efficient sonosensitizers, enabling broad‐spectrum bacterial eradication. To improve biocompatibility for in vivo sonodynamic therapy, the sonosensitizers are integrated into hydrogel matrix ...
Xinyue Lao, Qianqian Bai, Yifei Zhao, Xingyi Dai, Yuan Liu, Xiao Han, Jianhua Hao   +6 more
wiley   +1 more source

Designing effective solid catalysts for biomass conversion: aerobic oxidation of ethyl lactate to ethyl pyruvate

, 2018
The direct oxidative dehydrogenation of lactates with molecular oxygen is a promising route for producing bio-based pyruvates. But practical implementation of this route means high yields and mild conditions, which in turn require expensive noble-metal ...
Wei Zhang, B. Ensing, G. Rothenberg, N. R. Shiju   +3 more
semanticscholar   +1 more source

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

Advanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche, Ségolène Ladaigue, Giacomo Gropplero, Nicolas Zimmermann, Martin Nurmik, Irina Veith, Manh‐Louis Nguyen, Solenn Brosseau, Nicolas Poté, Pierre Mordant, Arnaud Roussel, Fathia Mami‐Chouaib, Fatima Mechta‐Grigoriou, Gérard Zalcman, Fabrice Soncin, Stéphanie Descroix, Maria Carla Parrini   +16 more
wiley   +1 more source

MECHANISM OF FORMATION OF OXALOACETATE AND PHOSPHOENOL PYRUVATE FROM PYRUVATE

THE JOURNAL OF VITAMINOLOGY, 1968
The pathways by which pyruvate, oxaloa cetate and P-enolpyruvate are interlinked have been reviewed. The enzymes involved (see Table 1) and pathways differ markedly in different cells. Animals and yeast possessing pyruvate carboxylase are able to convert pyruvate to oxaloacetate directly by CO2 fixation, but the propionic acid bacteria and E.
openaire   +4 more sources

Palladium-catalysed enolate arylation in the synthesis of aromatic heterocycles and substituted heterocycles [PDF]

, 2017
Chapter 1. Introduction A literature background on the early development of the Pd-catalysed cross-coupling reactions and the later discovery of the enolate arylation reaction is presented.
Esteves, Carlos Henrique Alves
core   +1 more source

Pulmonary Delivery of siRNA Anti‐TNFα‐loaded Lipid Nanoparticles for Rapid Recovery in Murine Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
In a murine model of acute lung injury, pulmonary administration of lipid nanoparticles carrying TNFα siRNA enables targeted delivery to immune cells. The study emphasises the importance of optimizing LNP distribution and delivery timing to improve therapeutic outcomes and develop emergency therapies for lung hyperinflammation.
Qinglin Wang, Jihana Achour, Laila Emam, Younes Louaguenouni, Catherine Cailleau, Françoise Mercier‐Nomé, Séverine Domenichini, Claudine Delomenie, Sezen Gul, Juliette Vergnaud, Nicolas Tsapis, Arnaud Mansart, Djillali Annane, Francois Fay, Elias Fattal   +14 more
wiley   +1 more source

Oxaloacetate as a Holy Grail Adjunctive Treatment in Gliomas: A Revisit to Metabolic Pathway. [PDF]

Cureus, 2023
Samad A, Samant R, Venkateshwara Rao K, Bhargava V, Sadique SI, Yadav R.   +5 more
europepmc   +1 more source

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

Advanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex, Ursula Menzel, Yann Ladner, Angela R. Armiento, Martin J. Stoddart   +4 more
wiley   +1 more source