Results 21 to 30 of about 689 (150)

Adjunctive antibacterial agents as a salvage therapy in relapsed vascular pythiosis patients

International Journal of Infectious Diseases, 2019
Human vascular pythiosis is a life-threatening condition caused by Pythium insidiosum. Patients with unresectable intra-abdominal artery involvement have not previously survived, despite being treated with antifungal agents and immunotherapy.
Navaporn Worasilchai, Nipat Chuleerarux, Pattama Torvorapanit   +2 more
exaly   +3 more sources

Simplified Point-of-Care Testing for Human Pythiosis: Development of a Whole-Blood-Based Lateral Flow Immunoassay [PDF]

Diagnostics
Background/Objectives: Human pythiosis, caused by Pythium insidiosum, is associated with severe morbidity and high mortality when diagnosis is delayed. Culture-based diagnosis is time-consuming and may be insensitive in clinical specimens, highlighting ...
Jidapa Szekely, Kitti Saelai, Sirida Youngchim, Siriporn Chongkae, Pornchanan Chanchay, Wiraphan Rakchang, Paramaporn Rattanaphan, Narongdet Kositpantawong   +7 more
doaj   +2 more sources

Worldwide distribution of human pythosis and biological characteristics of a Pythium insidiosum strain susceptible to antibiotics from China: a dual-scale study [PDF]

Frontiers in Medicine
IntroductionPythiosis, caused by Pythium insidiosum (P. insidiosum), is an emerging disease with high mortality and morbidity. Despite its clinical severity and geographical strain variations, diagnostic and treatment challenges persist.Materials and ...
Xiaoyun Liu, Qiuyue Diao, Mingliang Li, Yuting Yang, Jiayin Liang, Zehua Cui, Haiyan Zhang, Huiling He, Jiabao Huang, Hao Ren, Fengli Zhou, Tijiang Shan, Xiaopin Liao, Jian Sun, Kouxing Zhang, Kouxing Zhang   +15 more
doaj   +2 more sources

Needs assessment of a pythiosis continuing professional development program. [PDF]

PLoS Neglected Tropical Diseases
BackgroundPythiosis is a rare disease with high mortality, with over 94% of cases reported from Thailand and India. Prompt diagnosis and surgery improves patient outcomes.
Surachai Leksuwankun, Rongpong Plongla, Nathanich Eamrurksiri, Pattama Torvorapanit, Kasidis Phongkhun, Nattapong Langsiri, Tanaporn Meejun, Karan Srisurapanont, Jaedvara Thanakitcharu, Bhoowit Lerttiendamrong, Achitpol Thongkam, Kasama Manothummetha, Nipat Chuleerarux, Chatphatai Moonla, Navaporn Worasilchai, Ariya Chindamporn, Nitipong Permpalung, Saman Nematollahi   +17 more
doaj   +2 more sources

Potential anti-Pythium insidiosum therapeutics identified through screening of agricultural fungicides [PDF]

Microbiology Spectrum
Pythiosis is a life-threatening infectious disease caused by the oomycete Pythium insidiosum. Clinical manifestations of pythiosis include an eye, blood vessel, skin, or gastrointestinal tract infection. Pythiosis has been increasingly reported worldwide,
Hanna Yolanda, Kedchin Jearawuttanakul, Warawuth Wannalo, Phongthon Kanjanasirirat, Suparerk Borwornpinyo, Thidarat Rujirawat, Penpan Payattikul, Weerayuth Kittichotirat, Duangdao Wichadakul, Theerapong Krajaejun   +9 more
doaj   +2 more sources

Ex vivo observation of Pythium insidiosum-antigen treated neutrophils on three Pythium insidiosum strains isolated from vascular pythiosis patients [PDF]

Human Vaccines & Immunotherapeutics
The mechanisms of Pythium insidiosum-antigen (PIA) immunotherapy activating a patient’s immune system are unknown. We evaluated the interleukin-8 (IL-8) serum levels during P.
Sadeep Medhasi, Apichaya Sriwarom, Nitipong Permpalung, Pattama Torvorapanit, Rongpong Plongla, Ariya Chindamporn, Navaporn Worasilchai   +6 more
doaj   +2 more sources

M1.2 Human pythiosis [PDF]

Med Mycol, 2022
Abstract Meet the expert session, September 22, 2022, 8:00 AM - 9:00 AM Human pythiosis is a rare, life-threatening infection, which is generally caused by Pythium insidiosum, a fungal-like oomycete.
Plongla, Rongpong, Chindamporn, Ariya
europepmc   +2 more sources

Recent update in diagnosis and treatment of human pythiosis [PDF]

PeerJ, 2020
Human pythiosis is an infectious condition with high morbidity and mortality. The causative agent is the oomycete microorganism Pythium insidiosum. The pathogen inhabits ubiquitously in a wet environment, and direct exposure to the pathogen initiates the
Maria Nina Chitasombat, Passara Jongkhajornpong, Kaevalin Lekhanont, Theerapong Krajaejun   +3 more
doaj   +2 more sources

Ultrasound features of an unusual intramural gastric haemorrhage secondary to rodenticide intoxication in a dog

Veterinary Record Case Reports, Volume 11, Issue 4, December 2023., 2023
Abstract A 3‐year‐old, neutered, female, mix‐breed dog was presented with a history of acute haemorrhagic vomiting, diarrhoea, anorexia and lethargy. The patient had a hyperkinetic pulse, pale mucous membranes, bilateral hyphema and the capillary refill time was increased. Coagulation testing showed increased values.
Nuria Vallés, Marina S. Echalecu, Alejandra Bernabe, Juan Diego García, Amalia Agut   +4 more
wiley   +1 more source

Protein A/G-based enzyme-linked immunosorbent assay for detection of anti-Pythium insidiosum antibodies in human and animal subjects

BMC Research Notes, 2020
Objectives Pythiosis is a deadly infectious disease caused by Pythium insidiosum. Reports of both human and animal pythiosis are on the rise worldwide. Prognosis of the pythiosis patients relies on early diagnosis and prompt treatment.
Chalisa Jaturapaktrarak, Penpan Payattikul, Tassanee Lohnoo, Yothin Kumsang, Aree Laikul, Watcharapol Pathomsakulwong, Chompoonek Yurayart, Walaiporn Tonpitak, Theerapong Krajaejun   +8 more
doaj   +1 more source