Simplified Point-of-Care Testing for Human Pythiosis: Development of a Whole-Blood-Based Lateral Flow Immunoassay [PDF]
DiagnosticsBackground/Objectives: Human pythiosis, caused by Pythium insidiosum, is associated with severe morbidity and high mortality when diagnosis is delayed. Culture-based diagnosis is time-consuming and may be insensitive in clinical specimens, highlighting ...
Jidapa Szekely +7 more
doaj +2 more sources
Adjunctive antibacterial agents as a salvage therapy in relapsed vascular pythiosis patients
International Journal of Infectious Diseases, 2019 Human vascular pythiosis is a life-threatening condition caused by Pythium insidiosum. Patients with unresectable intra-abdominal artery involvement have not previously survived, despite being treated with antifungal agents and immunotherapy.
Nuttapon Susaengrat +2 more
exaly +3 more sources
Needs assessment of a pythiosis continuing professional development program. [PDF]
PLoS Neglected Tropical DiseasesBackgroundPythiosis is a rare disease with high mortality, with over 94% of cases reported from Thailand and India. Prompt diagnosis and surgery improves patient outcomes.
Surachai Leksuwankun +17 more
doaj +2 more sources
Ex vivo observation of Pythium insidiosum-antigen treated neutrophils on three Pythium insidiosum strains isolated from vascular pythiosis patients [PDF]
Human Vaccines & ImmunotherapeuticsThe mechanisms of Pythium insidiosum-antigen (PIA) immunotherapy activating a patient’s immune system are unknown. We evaluated the interleukin-8 (IL-8) serum levels during P.
Sadeep Medhasi +6 more
doaj +2 more sources
Clinical Features, Microbiological Characteristics, and Drug Sensitivity Analysis of Rare Human Spinal Pythiosis Strain [PDF]
Journal of FungiPythiosis, a rare and formidable infectious disease caused by Pythium insidiosum, is characterized by profound uncertainties in achieving definitive diagnoses, suboptimal outcomes, and an exceptionally high mortality rate. Here, we present a rare case of
Mingliang Li +8 more
doaj +2 more sources
Potential anti-Pythium insidiosum therapeutics identified through screening of agricultural fungicides [PDF]
Microbiology SpectrumPythiosis is a life-threatening infectious disease caused by the oomycete Pythium insidiosum. Clinical manifestations of pythiosis include an eye, blood vessel, skin, or gastrointestinal tract infection. Pythiosis has been increasingly reported worldwide,
Hanna Yolanda +9 more
doaj +2 more sources
Recent update in diagnosis and treatment of human pythiosis [PDF]
PeerJ, 2020 Human pythiosis is an infectious condition with high morbidity and mortality. The causative agent is the oomycete microorganism Pythium insidiosum. The pathogen inhabits ubiquitously in a wet environment, and direct exposure to the pathogen initiates the
Maria Nina Chitasombat +3 more
doaj +2 more sources
Veterinary Record Case Reports, Volume 11, Issue 4, December 2023., 2023 Abstract A 3‐year‐old, neutered, female, mix‐breed dog was presented with a history of acute haemorrhagic vomiting, diarrhoea, anorexia and lethargy. The patient had a hyperkinetic pulse, pale mucous membranes, bilateral hyphema and the capillary refill time was increased. Coagulation testing showed increased values.
Nuria Vallés +4 more
wiley +1 more source
Pitiose gastrointestinal canina: relato de caso no Pantanal brasileiro a partir de uma abordagem diagnóstica [PDF]
, 2022 A pitiose é causada por um organismo aquático semelhante a um fungo (Pythium insidiosum) e considerada um importante problema de saúde pública, pois pode afetar animais e humanos. Este artigo relata um caso de pitiose gastrointestinal em um cão.
Aguiar, Daniel Moura de +11 more
core +2 more sources